Results 81 to 90 of about 24,154 (199)

Characterisation of human hair follicle development

Journal of Anatomy, EarlyView.
Schematic of hair follicle development in human skin. Hair follicle primordia of similar sizes, but different densities, are laid out across the skin. The distinction between terminal and vellus hair sites is not obvious at early stages of hair follicle development.
Zoe R. Sudderick, James D. Glover, Cameron Batho‐Samblas, Barbara Bo‐Ju Shih, Denis J. Headon   +4 more
wiley   +1 more source

The Keystone‐Pathogen Hypothesis Updated: The Role of Porphyromonas gingivalis in Periodontitis

Journal of Periodontal Research, EarlyView.
Porphyromonas gingivalis orchestrates a coordinated manipulation of immune and inflammatory responses in periodontal tissues which leads to the generation of a dysbiotic, subgingival biofilm community, and progression of periodontitis. The type 9 secretion system, lipid A modification, and the formation of outer membrane vesicles are important ...
Mike A. Curtis, James A. Garnett, Richard P. Darveau   +2 more
wiley   +1 more source

yqhG Contributes to Oxidative Stress Resistance and Virulence of Uropathogenic Escherichia coli and Identification of Other Genes Altering Expression of Type 1 Fimbriae

Frontiers in Cellular and Infection Microbiology, 2019
Urinary tract infections (UTIs) are common bacterial infections and the vast majority of UTIs are caused by extraintestinal pathogenic Escherichia coli (ExPEC) strains referred to as uropathogenic E. coli (UPEC).
Hicham Bessaiah, Hicham Bessaiah, Pravil Pokharel, Pravil Pokharel, Hajer Habouria, Hajer Habouria, Sébastien Houle, Sébastien Houle, Charles M. Dozois, Charles M. Dozois   +9 more
doaj   +1 more source

The Oral‐Gut Axis: Bidirectional Interactions Between Microbiome and Diseases

Journal of Periodontal Research, EarlyView.
This study aims to summarize the mechanisms underlying ectopic colonization of the gut by oral pathobionts and the microbial and host factors that regulate this process. ABSTRACT Increased colonization of typically oral microorganisms is frequently observed in the gut mucosa or lumen of individuals with gastrointestinal disorders, including patients ...
Shinya Ebihara, Nobuhiko Kamada
wiley   +1 more source

Pilus phase variation switches gonococcal adherence to invasion by caveolin-1-dependent host cell signaling.

PLoS Pathogens, 2013
Many pathogenic bacteria cause local infections but occasionally invade into the blood stream, often with fatal outcome. Very little is known about the mechanism underlying the switch from local to invasive infection. In the case of Neisseria gonorrhoeae,
Michaela Faulstich, Jan-Peter Böttcher, Thomas F Meyer, Martin Fraunholz, Thomas Rudel   +4 more
doaj   +1 more source

Archaeal Cytoskeletal Protein CetZ1 Influences Assembly of the Motility Machinery

Molecular Microbiology, EarlyView.
The Haloferax volcanii tubulin‐like protein CetZ1 is required for rod‐cell morphogenesis and motility. We show that CetZ1 loss or GTPase inactivation impairs assembly of the motility machinery, including the archaellum base protein ArlD, the chemotaxis adaptor CheW1, and the response regulator CheY.
Hannah J. Brown, Md Imtiazul Islam, Juanfang Ruan, Matthew A. B. Baker, Solenne Ithurbide, Iain G. Duggin   +5 more
wiley   +1 more source

The Major Outer Membrane Protein MopB Is Required for Twitching Movement and Affects Biofilm Formation and Virulence in Two Xylella fastidiosa strains

Molecular Plant-Microbe Interactions, 2017
MopB is a major outer membrane protein (OMP) in Xylella fastidiosa, a bacterial plant pathogen that causes losses on many economically important crops. Based on in silico analysis, the uncharacterized MopB protein of X.
Hongyu Chen, Prem P. Kandel, Luisa F. Cruz, Paul A. Cobine, Leonardo De La Fuente   +4 more
doaj   +1 more source

Understanding Exosomes in Hair Regeneration

Periodontology 2000, EarlyView.
Abstract Background Alopecia is a prevalent condition correlated with significant psychosocial challenges, while contemporary treatments exhibit variable efficacy, require extended use, and may cause adverse effects. This review aimed to comprehensively assess exosome‐mediated interventions as a novel cell‐free regenerative approach for hair ...
Paras Ahmad, Catherine Davies, Anton Sculean, Richard J. Miron   +3 more
wiley   +1 more source

Artificial Catch Bonds: From Molecular Design to Network Mechanics

ChemSystemsChem, Volume 8, Issue 5, September 2026.
Catch bonds strengthen rather than weaken under force. This review follows the discovery and development of our understanding of this counterintuitive phenomenon, from the molecular mechanisms that produce it to the design rules for engineering it in DNA, proteins, and polymers, and on to the collective network mechanics enabling materials that stiffen
Hengfeng Jiang, Micah Yang, Isaac T. S. Li   +2 more
wiley   +1 more source

Type IV Pili Can Mediate Bacterial Motility within Epithelial Cells

mBio, 2019
Pseudomonas aeruginosa is among bacterial pathogens capable of twitching motility, a form of surface-associated movement dependent on type IV pili (T4P). Previously, we showed that T4P and twitching were required for P.
Vincent Nieto, Abby R. Kroken, Melinda R. Grosser, Benjamin E. Smith, Matteo M. E. Metruccio, Patrick Hagan, Mary E. Hallsten, David J. Evans, Suzanne M. J. Fleiszig   +8 more
doaj   +1 more source