Results 111 to 120 of about 25,462,782 (297)

A STRATEGY FOR DIRECT DELIVERY OF ANTIGENIC CONSTRUCTS TO DENDRITIC CELL RECEPTORS

open access: yesHematology, Transfusion and Cell Therapy
Objective: C-type lectin receptors (CLRs) expressed by DC are considered attractive targets for effective targeting of antigen to antigen-presenting cells, since the participation of CLRs can additionally stimulate antigen presentation and, accordingly ...
Anzhelika Melnikova   +2 more
doaj  

Cubical informal type theory: the higher groupoid structure [PDF]

open access: yesarXiv, 2018
Following a project of developing conventions and notations for informal type theory carried out in the homotopy type theory book for a framework built out of an augmentation of constructive type theory with axioms governing higher-dimensional constructions via Voevodsky's univalance axiom and higher-inductive types, this paper proposes a way of doing ...
arxiv  

Brucella NyxA and NyxB dimerization enhances effector function during infection

open access: yesFEBS Letters, EarlyView.
Brucella abortus thrives inside cells thanks to the translocation of effector proteins that fine‐tune cellular functions. NyxA and NyxB are two effectors that destabilize the nucleolar localization of their host target, SENP3. We show that the Nyx proteins directly interact with each other and that their dimerization is essential for their function ...
Lison Cancade‐Veyre   +4 more
wiley   +1 more source

The carboxylate “gripper” of the substrate is critical for C‐4 stereo‐inversion by UDP‐glucuronic acid 4‐epimerase

open access: yesFEBS Letters, EarlyView.
UDP‐glucuronic acid 4‐epimerase (UGAepi) catalyzes NAD+‐dependent interconversion of UDP‐glucuronic acid (UDP‐GlcA) and UDP‐galacturonic acid (UDP‐GalA) via C4‐oxidation, 4‐keto‐intermediate rotation, and C4‐reduction. Here, Borg et al. examined the role of the substrate's carboxylate group in the enzymic mechanism by analyzing NADH‐dependent reduction
Annika J. E. Borg   +2 more
wiley   +1 more source

Assessment of Type A Behaviour Pattern Among National Open University of Nigeria Academic Staff

open access: yesWest African Journal of Open and Flexible Learning, 2018
This study focused on assessment of Type A Behaviour Pattern (TABP) among academic staff of Open and Distance Learning. The Type A individuals of both sexes are considered to have the following characteristics: intense sustained drive to achieve set ...
JaneFrances O. Agbu   +2 more
doaj  

Polymorphic Type Inference for Machine Code [PDF]

open access: yesarXiv, 2016
For many compiled languages, source-level types are erased very early in the compilation process. As a result, further compiler passes may convert type-safe source into type-unsafe machine code. Type-unsafe idioms in the original source and type-unsafe optimizations mean that type information in a stripped binary is essentially nonexistent. The problem
arxiv  

B cell mechanobiology in health and disease: emerging techniques and insights into therapeutic responses

open access: yesFEBS Letters, EarlyView.
B cells sense external mechanical forces and convert them into biochemical signals through mechanotransduction. Understanding how malignant B cells respond to physical stimuli represents a groundbreaking area of research. This review examines the key mechano‐related molecules and pathways in B lymphocytes, highlights the most relevant techniques to ...
Marta Sampietro   +2 more
wiley   +1 more source

Botulinum Toxin Type B vs Type A in Cervical Dystonia: A Meta - analysis of high quality trials

open access: yesActa Neurológica Colombiana, 2012
Introduction: cervical dystonia (CD) is a frequent disabling condition. Botulinum Toxin (BT) type A is effective for CD. BT type B is an alternative, but its use for patients who develop neutralizing antibodies against BT type A is debatable ...
Diana M. Prada G
doaj   +2 more sources

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