Results 111 to 120 of about 12,021,669 (295)

Management of Type A Aortic Dissection in the Emergency Department: A Comprehensive Case Report

open access: yesCurrent Medical Issues
This case report elucidates the presentation and management of a 54-year-old man with type A aortic dissection (TAAD) in the emergency department. The patient, a known diabetic with uncontrolled hypertension and a history of heavy smoking, presented with
Aya Hasan Aalhamad   +2 more
doaj   +1 more source

Immunity to hepatitis A virus among working professionals in Poland – Results of a 3-year serological survey 2013–2015

open access: yesAnnals of Agricultural and Environmental Medicine, 2018
Introduction Hepatitis A (HA) is caused by infection with the hepatitis A virus (HAV). The differential etiological diagnosis of acute hepatitis is based on a positive result of the serological test detecting IgM class anti-HAV.
Grzegorz Juszczyk   +6 more
doaj   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

A model to estimate the lifetime health outcomes of patients with Type 2 diabetes: the United Kingdom Prospective Diabetes Study (UKPDS) Outcomes Model (UKPDS no. 68) [PDF]

open access: yes, 2004
<i>Aims/hypothesis</i> The aim of this study was to develop a simulation model for Type 2 diabetes that can be used to estimate the likely occurrence of major diabetes-related complications over a lifetime, in order to calculate health ...
Stevenson, R.J.   +27 more
core   +1 more source

Several Types of Types in Programming Languages [PDF]

open access: yes, 2016
Types are an important part of any modern programming language, but we often forget that the concept of type we understand nowadays is not the same it was perceived in the sixties. Moreover, we conflate the concept of "type" in programming languages with the concept of the same name in mathematical logic, an identification that is only the result of ...
openaire   +2 more sources

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Aspect−Oriented Programming with Type Classes

open access: yes, 2007
We consider the problem of adding aspects to a strongly typed language which supports type classes. We show that type classes as supported by the Glasgow Haskell Compiler can model an AOP style of programming via a simple syntax-directed transformation ...
Sulzmann, Martin   +5 more
core   +1 more source

Immunology and genetics of type 1 diabetes [PDF]

open access: yes, 2008
Type 1 diabetes is one of the most well-characterized autoimmune diseases. Type 1 diabetes compromises an individual's insulin production through the autoimmune destruction of pancreatic Β-cells.
Omenn, Gilbert S.   +5 more
core   +1 more source

Type Systems for Systems Types

open access: yes, 2019
This thesis presents a framework aimed at significantly reducing the cost of proving functional correctness for low-level operating systems components, designed around a new programming language, Cogent. This language is total, polymorphic, higher-order, and purely functional, including features such as algebraic data types and type inference ...
openaire   +3 more sources

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

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