Results 241 to 250 of about 25,462,782 (297)

Survey of feeding issues experienced by patients with spinal muscular atrophy type 2 in Japan. [PDF]

J Phys Ther Sci
Uchio Y, Ikai T.
europepmc   +1 more source

Targeted protein degradation in oncology: novel therapeutic opportunity for solid tumours?

Molecular Oncology, EarlyView.
Current anticancer therapies are limited by the occurrence of resistance and undruggability of most proteins. Targeted protein degraders are novel, promising agents that trigger the selective degradation of previously undruggable proteins through the recruitment of the ubiquitin–proteasome machinery. Their mechanism of action raises exciting challenges,
Noé Herbel, Sophie Postel‐Vinay
wiley   +1 more source

The skeletal muscle response to high-intensity training assessed by single-nucleus RNA-sequencing is blunted in individuals with type 2 diabetes. [PDF]

J Physiol
Hansen M, Grothen JER, Karlsen A, Martinez JM, Sidiropoulos N, Helge JW, Pedersen TÅ, Dela F.   +7 more
europepmc   +1 more source

Catalogue of the type fossils in the Woodwardian museum, Cambridge, with a preface by T. M. Hughes.

, 1891
Henry Woods
openalex   +2 more sources

Aberrant expression of nuclear prothymosin α contributes to epithelial‐mesenchymal transition in lung cancer

Molecular Oncology, EarlyView.
Nuclear prothymosin α inhibits epithelial‐mesenchymal transition (EMT) in lung cancer by increasing Smad7 acetylation and competing with Smad2 for binding to SNAI1, TWIST1, and ZEB1 promoters. In early‐stage cancer, ProT suppresses TGF‐β‐induced EMT, while its loss in the nucleus in late‐stage cancer leads to enhanced EMT and poor prognosis.
Liyun Chen, Chung‐Teng Wang, Jia‐Ming Chang, Ai‐Li Shiau, Gia‐Shing Shieh, Yau‐Lin Tseng, Yi‐Ting Yen, Tang‐Hsiu Huang, Li‐Hsin Cheng, Yu‐Chih Wu, Chao‐Liang Wu, Bing‐Hua Su, Pensee Wu   +12 more
wiley   +1 more source

Serum Periostin is Able to Stratify Type 2-Dominant Ulcerative Colitis. [PDF]

Inflamm Bowel Dis
Takedomi H, Nunomura S, Nanri Y, Honda Y, Yokomizo K, Akutagawa T, Tsuruoka N, Sakata Y, Conway S, Kawaguchi A, Aishima S, Esaki M, Izuhara K.   +12 more
europepmc   +1 more source

The Heritability of Official Type Ratings and the Correlation between Type Ratings and Butter–Fat Production of Ayrshire Cows

, 1948
William J. Tyler, George Hyatt
openalex   +1 more source

Determination of ADP/ATP translocase isoform ratios in malignancy and cellular senescence

Molecular Oncology, EarlyView.
The individual functions of three isoforms exchanging ADP and ATP (ADP/ATP translocases; ANTs) on the mitochondrial membrane remain unclear. We developed a method for quantitatively differentiating highly similar human ANT1, ANT2, and ANT3 using parallel reaction monitoring. This method allowed us to assess changes in translocase levels during cellular
Zuzana Liblova, Dominika Maurencova, Barbora Salovska, Marek Kratky, Tomas Mracek, Zuzana Korandova, Alena Pecinova, Pavla Vasicova, David Rysanek, Ladislav Andera, Ivo Fabrik, Rudolf Kupcik, Pavel Kashmel, Pinky Sultana, Vojtech Tambor, Jiri Bartek, Josef Novak, Marie Vajrychova, Zdenek Hodny   +18 more
wiley   +1 more source

Single-cell chromatin accessibility profiling reveals regulatory mechanisms and evolution in pig brains. [PDF]

BMC Biol
Xiang Y, Zhang S, Huang Y, Zheng Z, Sun J, Zhao Q, Zhou P, Qi X, Li J, Xiong F, Xu J, Wang S, Fu L, Li X.   +13 more
europepmc   +1 more source

Different Types of Milk, their Relation to the Rennet, and their Importance in Cheesemaking

, 1925
A.G. Koestler
openalex   +1 more source