Results 251 to 260 of about 139,845,986 (286)

Generation and Characterization of Single-Domain Antibodies Against the D-Antigen of Sabin Poliovirus Types 2 and 3. [PDF]

Viruses
Ermakova M, Ivanov S, Shmeleva O, Borisenko N, Zyrina A, Levin I, Chumakov S, Shishova A, Ivin Y, Piniaeva A, Siniugina A, Ishmukhametov A.   +11 more
europepmc   +1 more source

Reprogramming tumor cells with LCOR mRNA nanotherapy to enhance immunotherapy

Molecular Oncology, EarlyView.
LCOR (Ligand‐dependent corepressor) mRNA encapsulated in polymeric nanoparticles restores LCOR activity in tumor cells, constraining aggressive tumor cell states and increasing tumor immunogenicity. This reprogramming makes tumor cells more vulnerable to T‐cell attack and enhances their response to immune‐checkpoint immunotherapy.
Gabriel Serra‐Mir, Elena Haro‐Martínez, Sandra Blasco‐Benito, Chiara Cannatà, José Ángel Palomeque, Anna López‐Plana, Maria Sanz‐Flores, Marc Sabartés, Cristina Fornaguera, Toni Celià‐Terrassa   +9 more
wiley   +1 more source

Balancing clinical benefits and behavioral risks of obesity-focused management in youth-onset type 2 diabetes: A narrative review. [PDF]

touchREV Endocrinol
Chivate R, Christian C, Hartman A, Dhali A, Goldschmidt AB, Vajravelu ME.   +5 more
europepmc   +1 more source

Engineering IL‐4 resistant proinflammatory human myeloid cells for cancer immunotherapy

Molecular Oncology, EarlyView.
We developed a scalable workflow to generate proinflammatory human myeloid cells. CRISPR/Cas9‐edited CD34+ hematopoietic stem and progenitor cells were expanded and differentiated with M‐CSF. Deletion of STAT6 or STAT6/NFKB1 enhanced macrophage proinflammatory gene expression and cytokine secretion in the presence of IL‐4 while maintaining antibody ...
Theresa Barberi, Alan D. Friedman
wiley   +1 more source

Spiral Jejunal Reconstruction of Both Pancreatic Stumps in Type II Portal Annular Pancreas during Pancreaticoduodenectomy: A Case Report. [PDF]

Surg Case Rep
Suzuki H, Ishikawa K, Bamba T, Nakano M, Inagaki Y, Hamada K, Shoji S, Mori M.   +7 more
europepmc   +1 more source

Internal Aspiration in Macular Hole Surgery: A Retrospective Comparative Study. [PDF]

J Ophthalmol
Xu K, Liao Y, Li D, Cui S, Feng X, Wang C, Chen H.   +6 more
europepmc   +1 more source

Distinct chalcophile-element inheritance from subducted continental crust in metasomatized mantle. [PDF]

Sci Adv
Wang Z, Wang X, Xu H, Zhang J, Jenner FE, Foley S, Ma L, Chen K, Sun J, Zong K, Liu Y, Li J, Zhang J, Hu Z.   +13 more
europepmc   +1 more source

The <i>JAK2</i> V617F revolution in myeloproliferative neoplasms. [PDF]

Haematologica
Tefferi A.
europepmc   +1 more source

Temperature Dependence of Space Charge Retention in Bulk Acrylic. [PDF]

Adv Sci (Weinh)
Clifford BC, Sturge KM, Hoppis N, Frashure EH, Cumings J, Koeth TW.   +5 more
europepmc   +1 more source