Results 21 to 30 of about 47,460 (264)

Aortic Dissection that Presented to a Tertiary Hospital's ED in Dubai, UAE: A Descriptive Study

open access: yesSaudi Journal of Emergency Medicine
Background: Aortic dissection is a life-threatening condition, with a high mortality rate. It can be classified into Stanford type A or type B. This study analyzes the clinical presentation, risk factors, systolic blood pressure, and the mortality rate ...
Ivyan Kambal   +4 more
doaj   +1 more source

Role of Echocardiography as Supporting Diagnostic Modality in Localized Stanford Type A Aortic Dissection

open access: yesMajalah Kardiologi Indonesia, 2016
Ascending Stanford type A aortic dissection carries a high morbidity and mortality. Proper identification of the proximal origin of the dissection and determination of concomitant aortic valve involvement significantly facilitate surgical repair which ...
Haris Munirwan   +8 more
doaj   +1 more source

Type A Aortic Dissection Complicated by Pheochromocytoma [PDF]

open access: yesThe Annals of Thoracic Surgery, 2019
This report presents a case of aortic dissection as the patient's initial presentation of an undiagnosed pheochromocytoma. A 36-year-old man presented with substernal chest pressure and abdominal pain. Computed tomography revealed type A aortic dissection with a 3.6-cm left adrenal mass. Elevated catecholamine levels were diagnostic of pheochromocytoma.
Brianne, Runyan   +4 more
openaire   +2 more sources

Increased risk for the development of postoperative severe hypoxemia in obese women with acute type a aortic dissection

open access: yesJournal of Cardiothoracic Surgery, 2019
Background The purpose of this study is to identify the risk factors for postoperative severe hypoxemia after surgery for acute type A aortic dissection.
Ming Gong   +6 more
doaj   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

open access: yesFEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang   +2 more
wiley   +1 more source

The relationship between quality of life and health promotion behavior in patients with type B aortic dissection: a cross-sectional study

open access: yesJournal of Cardiothoracic Surgery, 2023
Background To understand the current situation of health promotion behavior and quality of life among aortic dissection survivors and the correlation between them. Methods Sociodemographic characteristics were collected. T-test and variance analysis were
Jianxin Tu   +5 more
doaj   +1 more source

Type A Aortic Dissection with Antegrade Intimointimal Intussusception

open access: yesMethodist DeBakey Cardiovascular Journal, 2023
We describe a 60-year-old man with a history of hypertension who presented to an outside emergency department with chest pain and left lower extremity numbness and weakness.
Christine Lannon   +6 more
doaj   +1 more source

Re‐Purposing Sapropterin (Kuvan) for ACTA2‐Related Multisystemic Smooth Muscle Dysfunction Syndrome: A Translational Mechanistic and First‐In‐Human Therapeutic Report

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Multisystemic smooth muscle dysfunction syndrome (MSMDS) is an ultra‐rare, ACTA2‐related disorder characterized by severe cerebrovascular disease, aortic aneurysms, and smooth muscle dysfunction. Using molecular dynamics simulations and in silico drug screening, we identified that sapropterin dihydrochloride (Kuvan) is a candidate capable of ...
Moran Hausman‐Kedem   +9 more
wiley   +1 more source

Advances in 3D Bioprinting for Breast Cancer Modeling: Tumor Microenvironment, Metastasis, and Drug Screening

open access: yesAdvanced Healthcare Materials, EarlyView.
Three‐dimensional bioprinting transforms breast cancer modeling from simple constructs into spatially organized, multicellular, perfused, and patient‐derived platforms. This review shows how bioinks, cellular composition, architecture, and flow govern tumor behavior and drug response, while revealing why complexity alone is insufficient without ...
Mustafa Nakipoglu   +7 more
wiley   +1 more source

Aortic Dissection that Presented to a Tertiary Hospital’s ED in Dubai, UAE: A Descriptive Study with Literature Review

open access: yesDubai Medical Journal
Objectives: Aortic dissection is a life-threatening condition, with a high mortality rate. It can be classified into Stanford type A or type B. This study reports the clinical presentation, risk factors, systolic blood pressure, and the mortality rate ...
Ivyan Kambal   +4 more
doaj   +1 more source

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