ADAM17 and its proteolytic targets in disease pathogenesis
ADAM17 as a multifunctional sheddase with contrasting roles across inflammatory, metabolic, cardiovascular, and neoplastic diseases. Through regulated activation by iRhom, iTAP/FRMD8, and tetraspanins, ADAM17 cleaves diverse membrane ligands and receptors, thereby promoting inflammation, fibrosis, obesity, insulin resistance, and tumor progression ...
Abdulbasit Amin, Marina Badenes
wiley +1 more source
Clinical follow-up and predictors of re-intervention following thoracic endovascular aortic repair for Stanford type B aortic dissection. [PDF]
Liu X +6 more
europepmc +1 more source
Deep reinforcement learning for automatic anatomic CT landmark localization in Stanford Type B aortic dissection. [PDF]
Bäumler K +16 more
europepmc +1 more source
Cyclin‐dependent kinase 13 is indispensable for normal mouse heart development
Congenital heart disease (CHD) is the most common defect in live births. The role of cyclin‐dependent kinase (CDK13) in cardiogenesis and CHD was studied using a transgenic mouse model (Cdk13tm1b) carrying deletion of exons 3 and 4, causing loss of function.
Qazi Waheed‐Ullah +8 more
wiley +1 more source
Clinical and financial outcomes associated with gastrointestinal complications among patients with type B aortic dissection. [PDF]
Coaston TN +6 more
europepmc +1 more source
Innovation and the role of the cardiac morphologist [PDF]
Aiello, VD +4 more
core +1 more source
We review the characteristic changes to the limb soft tissue and neurovascular abnormalities that have been described in the congenital limb birth defect, Radial Dysplasia. These include consistent changes in muscle anatomy or absence of specific muscles, persistent median arteries and absent radial arteries and consistent alterations in neural ...
Marco Correia Duarte +6 more
wiley +1 more source
Suitability of Single-Branched Thoracic Endografts for the Treatment of Acute Type B Aortic Dissection-An Anatomical Feasibility and Comparative Study. [PDF]
Lang J +4 more
europepmc +1 more source
Periodontal Medicine Rewired: Mechanisms Linking Periodontitis to Systemic Diseases
This review reorganizes decades of research in periodontal medicine into a multi‐dimensional framework, illustrating how periodontitis influences systemic health through at least seven interconnected mechanisms. ABSTRACT Periodontitis is now recognized not merely as a localized oral condition but as a systemic disease linked to over 70 communicable and
Mario Romandini +3 more
wiley +1 more source

