Results 71 to 80 of about 19,624,843 (301)

Expert Management of Type B Aortic Dissection From Onset With Thoracic Endovascular Aortic Repair

Annals of Thoracic Surgery Short Reports
Background: Thoracic endovascular aortic repair is a key treatment of acute type B aortic dissection. We recognized the importance of managing type B aortic dissections from their onset and established our strategy in 2013.
Katsuhiko Oda, MD, PhD, Makoto Takahashi, MD, PhD, Ryuichi Taketomi, MD, PhD, Rina Akanuma, MD, Takahiko Hasegawa, MD, Satoshi Kawatsu, MD, PhD   +5 more
doaj   +1 more source

Retrograde type A dissection after thoracic endovascular aortic repair for type B aortic dissection [PDF]

Journal of Vascular Surgery, 2019
The purpose of this study was to evaluate clinical, anatomic, and procedural characteristics of patients who developed retrograde type A dissection (RTAD) after thoracic endovascular aortic repair (TEVAR) for type B aortic dissection (TBAD).Between January 2012 and January 2017, there were 186 patients who underwent TEVAR for TBAD at a ...
Halim, Yammine, Charles S, Briggs, Gregory A, Stanley, Jocelyn K, Ballast, William E, Anderson, Tzvi, Nussbaum, Jeko, Madjarov, John R, Frederick, Frank R, Arko   +8 more
openaire   +2 more sources

A new mechanism by which an acute type B aortic dissection is primarily complicated, becomes complicated, or remains uncomplicated

, 2012
This study is to evaluate if different locations of the primary entry tear result in primary complicated, secondary complicated, or uncomplicated acute type B aortic ...
Czerny, Martin, Dumfarth, Julia, Lammer, Johannes, Ta, Julie, Grimm, Michael, Funovics, Martin, Loewe, Christian, Sodeck, Gottfried H, Schoder, Maria, Ehrlich, Marek   +9 more
core   +1 more source

An Extracellular Pore‑Targeting Peptide Defines a Designable Allosteric Site in TRPV2

Advanced Science, EarlyView.
Structure‐guided peptide engineering yields Depiv2, a highly potent and subtype‐selective TRPV2 inhibitor that binds to the extracellular pore and remodels it into a closed, non‐conductive state. Depiv2 suppresses pathological cardiac hypertrophy, establishing the TRPV2 outer pore as a designable interface for selective peptide modulation.
Aiqin Zhu, Hongkun Wang, Jiawei Wang, Xiaolu Liu, Aerziguli Aierken, Lizhen Xu, Ping Liang, Fan Yang   +7 more
wiley   +1 more source

Salvianolic Acid a Disrupts the HSP90α‐AKT‐PERK Ternary Complex to Alleviate Atherosclerosis by Activating Endoplasmic Reticulum Stress of Senescent Vascular Smooth Muscle Cells

Advanced Science, EarlyView.
Salvianolic acid A (SAA) selectively induces senescent vascular smooth muscle cell apoptosis, alleviating atherosclerosis. Mechanistically, SAA targets heat shock protein 90 alpha (HSP90α) to disrupt the protein inase B (AKT)‐PRKR‐Like Endoplasmic Reticulum Kinase (PERK) scaffold, driving ubiquitin‐proteasome‐dependent AKT degradation.
Xiuya Guan, Mengkai Lu, Xinhai Cui, Dawei Zhang, Lei Zhang, Lin Lin, Yuan Li, Yuanlong Hu, Chao Li   +8 more
wiley   +1 more source

Treatment for Stanford type B aortic dissection with insufficient anchoring region using castor integrated branched aortic stent graft

Frontiers in Cardiovascular Medicine
BackgroundTo investigate the clinical efficacy of Castor integrated branched aortic stent graft for the treatment of Stanford type B aortic dissection with insufficient anchoring area.MethodsRetrospective analysis of clinical data of 26 patients with ...
Weiqing Chen, Dabing Liu, Tao Chen, Jian Liu, Yi Guo, Bo Ye   +5 more
doaj   +1 more source

Morphologic predictors of aortic dilatation in type B aortic dissection [PDF]

Journal of Vascular Surgery, 2013
Conservative management of acute type B aortic dissection (ABAD) is often associated with aortic dilatation during follow-up increasing the risk of aortic rupture. The goal of this study was to investigate whether morphologic characteristics of the dissection can predict aortic growth.All conservatively managed ABAD patients from four referral centers ...
J. L. Tolenaar, J. W. Van Keulen, F. H. W. Jonker, J. A. Van Herwaarden, H. J. Verhagen, F. L. Moll, B. E. Muhs, S. Trimarchi   +7 more
openaire   +3 more sources

Quality of life after acute type B dissection in the era of thoracic endovascular aortic repair

, 2010
Conservative management of acute type B aortic dissection is currently being challenged by primary thoracic endovascular aortic repair. Aim was to assess outcome and quality of life after these different approaches using an adjusted standard population ...
Carrel, T P, Schmidli, J, Immer, Franz F, Hinder, D, Dick, F, Dai-Do, D, Hirzel, C, Hinder D, Hirzel C, Dai-Do D, Immer FF, Dick, Florian, Schmidli, Jürg, Dick F, Carrel, Thierry, Carrel TP, Schmidli J   +16 more
core   +1 more source

Ilexoside K Ameliorates Atherosclerosis by Suppressing CD72hi Macrophages and Blocking CXCL12–CXCR4 Axis to Inhibit Endothelial Pyroptosis

Advanced Science, EarlyView.
CD72hi macrophages drive endothelial pyroptosis and accelerate atherosclerosis through CXCL12–CXCR4‐mediated immune–vascular crosstalk. Ilexoside K suppresses this pathogenic communication by modulating CXCR4‐dependent endothelial responses, reducing inflammation and plaque progression. These findings reveal a macrophage–endothelial regulatory axis and
Xingling He, Sijing Li, Jiahui Chen, Liyu Lin, Xinyu Li, Xiaojiao Zhang, Yihui Zhang, Xingling Chen, Jinjian Guo, Zhongqi Yang, Lu Lu, Shihao Ni   +11 more
wiley   +1 more source

Retrograde Type A Aortic Dissection after Thoracic Endovascular Aortic Repair for Type B Dissection

The Heart Surgery Forum, 2020
Background: A 64-year-old woman presented with dilatation of the distal aortic arch secondary to chronic type B aortic dissection. Case Report: The patient underwent fenestrated thoracic endovascular aortic repair (TEVAR) for closure of the entry site, and reconstruction of the left subclavian artery with a covered stent. On the 40th postoperative day,
Masato, Hayakawa, Takaaki, Nagano, Isao, Nishijima, Kento, Shinzato, Ryo, Ikemura, Kazufumi, Miyagi, Kiyoshi, Iha, Shigenobu, Senaha, Mitsuyoshi, Shimoji, Mitsuru, Akasaki   +9 more
openaire   +3 more sources