Results 81 to 90 of about 19,624,843 (301)

Predictors of aortic growth in uncomplicated type B aortic dissection [PDF]

Journal of Vascular Surgery, 2014
Patients with uncomplicated acute type B aortic dissection (ABAD) generally can be treated with conservative medical management. However, these patients may develop aortic enlargement during follow-up, with the risk for rupture, which necessitates intervention.
van Bogerijen, Guido H.W., Tolenaar, Jip L., Rampoldi, Vincenzo, Moll, Frans L., van Herwaarden, Joost A., Jonker, Frederik H.W., Eagle, Kim A., Trimarchi, Santi   +7 more
openaire   +2 more sources

A Spatiotemporal Single‐Cell Atlas Uncovers Dysregulated ECM Dynamics and Septal Remodeling Arrest in Human Ventricular Septal Defects

Advanced Science, EarlyView.
Integrating single‐cell and spatial transcriptomics reveals human ventricular septal defect (VSD) as a disease of microenvironmental insufficiency and structural remodeling arrest. Attenuated endothelial‐fibroblast crosstalk, alongside downregulated THBS1/TGF‐β1 and MMP2 signaling networks, impairs the endothelial‐to‐mesenchymal transition (EndoMT) and
Xiaoyuan Zhang, Lun Zhu, Ze Sun, Ruolin Jia, Ziming Wang, Jiayao Zhao, Bohao Liu, Haiqing Xiong, Xiaowei Yu, Yanzhu Yue   +9 more
wiley   +1 more source

Stanford type B aortic dissection is more frequently associated with coronary artery atherosclerosis than type A

Journal of Cardiothoracic Surgery, 2018
Background The relationship between aortic dissection and coronary artery disease is not clear. The purpose of this study was to clarify the difference in the rate of coronary artery atherosclerosis between Stanford type A and type B aortic dissection by
Naoki Hashiyama, Motohiko Goda, Keiji Uchida, Yukihisa Isomatsu, Shinichi Suzuki, Makoto Mo, Takahiro Nishida, Munetaka Masuda   +7 more
doaj   +1 more source

NCOA4 Accelerates Abdominal Aortic Aneurysm Formation by Regulating Macrophage Activation and Ferroptosis via STAT1–CH25H Axis

Advanced Science, EarlyView.
Under pathological stimulation, NCOA4 in macrophages interacts with STAT1 to promote CH25H transcription. The subsequent increase in 25‐HC production activates macrophages, triggers inflammatory responses and ferroptosis, and accelerates the progression of AAA.
Zhinan Wu, Yuxuan Qian, Wenyi Xu, Fei Liao, Xueliang Liu, Xiao Kuang, Guqing Luo, Xinjie He, Lixian Jiang, Song Ding   +9 more
wiley   +1 more source

Aortic Complications Associated With Pregnancy in Marfan Syndrome: The NHLBI National Registry of Genetically Triggered Thoracic Aortic Aneurysms and Cardiovascular Conditions (GenTAC)

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2016
BackgroundThe risk of aortic complications associated with pregnancy in women with Marfan syndrome (MFS) is not fully understood. Methods and ResultsMFS women participating in the large National Registry of Genetically Triggered Thoracic Aortic Aneurysms
Mary J. Roman, Norma L. Pugh, Tabitha P. Hendershot, Richard B. Devereux, Hal Dietz, Kathryn Holmes, Kim A. Eagle, Scott A. LeMaire, Dianna M. Milewicz, Shaine A. Morris, Reed E. Pyeritz, William J. Ravekes, Ralph V. Shohet, Michael Silberbach   +13 more
doaj   +1 more source

Mid-Term Results of Thoracic Endovascular Aortic Repair for Complicated Acute Type B Aortic Dissection at a Single Center

Journal of Chest Surgery, 2021
Background: Complicated acute type B aortic dissection is a life-threatening condition with high morbidity and mortality. The aim of this study was to report a single-center experience with endovascular stent-graft repair of acute type B dissection of ...
Young Kwang Hong, Won Ho Chang, Dong Erk Goo, Hong Chul Oh, Young Woo Park   +4 more
doaj   +1 more source

Interdisciplinary expert consensus document on management of type B aortic dissection

, 2013
An expert multidisciplinary panel in the treatment of type B aortic dissection reviewed available literature to develop treatment algorithms using a consensus method.
Czerny, Martin, De Rango, Paola, Nienaber, Christoph, Schepens, Marc, Fattori, Rossella, Marc Schepens, Rossella Fattori, Cao, Piergiorgio, Rousseau, Hervé, Arturo Evangelista, Christoph Nienaber, Piergiorgio Cao, Martin Czerny, Hervé Rousseau, Paola De Rango, Evangelista, Arturo   +15 more
core   +1 more source

Acute thoracic aortic dissection (Stanford B): challenges in early detection and management [PDF]

, 2015
Background: Diagnosis of acute thoracic dissection is crucial given its potential fatal complications in delayed treatment response. Early and appropriate intervention renders obviation of futile surgery.
Ahmad Saad, Fathinul Fikri, Abdullah, Noraini Sarina   +1 more
core   +2 more sources

Lactate Signal: Modulator of Cellular Energy Production and Anabolism

Advanced Science, EarlyView.
Compartmentalized lactate signaling provides a spatial framework for understanding how lactate‐rich states are generated, transported, sensed, and translated into biological outputs. This Review integrates extracellular, cytosolic, mitochondrial‐associated, and nuclear lactate mechanisms to explain how lactate shapes metabolic adaptation, immune ...
Han Wang, Si‐Yuan Yang, Wei Xu
wiley   +1 more source

Descending aortic diameter of 5.5 cm or greater is not an accurate predictor of acute type B aortic dissection

, 2011
ObjectiveThe risk of acute type B aortic dissection is thought to increase with descending thoracic aortic diameter. Currently, elective repair of the descending thoracic aorta is indicated for an aortic diameter of 5.5 cm or greater.
T. Myrmel, A. Evangelista, C. A. Nienaber, Bart E. Muhs, Santi Trimarchi, G. Meinhardt, V. Rampoldi, Reed E. Pyeritz, L. A. Pape, Thoralf M. Sundt, T. M. Sundt, Kim A. Eagle, R. E. Pyeritz, K. A. Eagle, Linda A. Pape, Himanshu J. Patel, Arturo Evangelista, Truls Myrmel, E. M. Isselbacher, S. Trimarchi, Frederik H.W. Jonker, J. B. Froehlich, Alan T. Hirsch, B. E. Muhs, S. Hutchison, Viviana Grassi, Gabriel Meinhardt, V. Grassi, James B. Froehlich, H. J. Patel, A. T. Hirsch, Vincenzo Rampoldi, Eric M. Isselbacher, Christoph A. Nienaber, J. Beckman, Joshua Beckman, F. H. Jonker, Stuart Hutchison   +37 more
core   +1 more source