Results 91 to 100 of about 15,925,070 (360)
Sex and Gender Differences in Risk, Pathophysiology and Complications of Type 2 Diabetes Mellitus
Endocrine reviews, 2016 The steep rise of type 2 diabetes mellitus (T2DM) and associated complications go along with mounting evidence of clinically important sex and gender differences.
A. Kautzky-Willer +2 more
semanticscholar +1 more source
A stepwise emergence of evolution in the RNA world
FEBS Letters, EarlyView.How did biological evolution emerge from chemical reactions? This perspective proposes a gradual scenario of self‐organization among RNA molecules, where catalytic feedback on random mixtures plays the central role. Short oligomers cross‐ligate, and self‐assembly enables heritable variations. An event of template‐externalization marks the transition to
Philippe Nghe
wiley +1 more source
Advertisement for Trapper Nelson\u27s Indian Pack Boards [PDF]
, 2015 This advertisement shows the type of hiking materials that were popular before the advent of plastics and polymers. In her book Not Just Trees, Dr. Jane Claire Dirks-Edmunds writes about the texture of the cloth and materials she used during fieldwork on
Trager, Charles
core +1 more source
The emerging role of targeting cancer metabolism for cancer therapy
Tumor Biology, 2020 Glucose, as the main consuming nutrient of the body, faces different destinies in cancer cells. Glycolysis, oxidative phosphorylation, and pentose phosphate pathways produce different glucose-derived metabolites and thus affect cells’ bioenergetics ...
Pegah Farhadi +3 more
doaj +1 more source
FEBS Letters, EarlyView.The enzyme 5‐lipoxygenase (5‐LOX) catalyzes the first step in the biosynthesis of leukotrienes (LTs) involved in inflammatory pathophysiology. After cellular stimulation, 5‐LOX translocates to the nucleus, interacting with the 5‐LOX‐activating protein (FLAP) to form LTA4 from arachidonic acid (AA).
Erik Romp +5 more
wiley +1 more source
Construction of minimal DFAs from biological motifs [PDF]
, 2010 Deterministic finite automata (DFAs) are constructed for various purposes in computational biology. Little attention, however, has been given to the efficient construction of minimal DFAs.
Marschall, Tobias
core
Poultry Science, 2022 : This study investigated the effects of Bacillus coagulans X26 on the production performance, egg quality, intestinal structure, intestinal short-chain fatty acids, and microbial diversity of laying hens during the peak laying period and explored the ...
Li Xu +6 more
doaj
FEBS Letters, EarlyView.UDP‐glucuronic acid 4‐epimerase (UGAepi) catalyzes NAD+‐dependent interconversion of UDP‐glucuronic acid (UDP‐GlcA) and UDP‐galacturonic acid (UDP‐GalA) via C4‐oxidation, 4‐keto‐intermediate rotation, and C4‐reduction. Here, Borg et al. examined the role of the substrate's carboxylate group in the enzymic mechanism by analyzing NADH‐dependent reduction
Annika J. E. Borg +2 more
wiley +1 more source
Adipocyte, 2020 T2D is a complex disease with poorly understood mechanisms. In Asian Indians, it is associated with “thin fat” phenotype which resembles with partial lipodystrophy. We hypothesized that disturbed expression of lipodystrophy genes might play a role in T2D
Aditya Saxena +4 more
doaj +1 more source
FEBS Letters, EarlyView.B cells sense external mechanical forces and convert them into biochemical signals through mechanotransduction. Understanding how malignant B cells respond to physical stimuli represents a groundbreaking area of research. This review examines the key mechano‐related molecules and pathways in B lymphocytes, highlights the most relevant techniques to ...
Marta Sampietro +2 more
wiley +1 more source