Results 121 to 130 of about 15,878,608 (386)

HTR1A Gene Polymorphism in Type 2 Diabetes Mellitus Comorbid with Major Depressive Disorder in a Chinese Population

open access: yesDiabetes, Metabolic Syndrome and Obesity, 2022
Dilixia Simayi,1,2 Yaqun Guan1 1State Key Laboratory of Pathogenesis, Prevention and Treatment of High Incidence Diseases in Central Asia, Xinjiang Key Laboratory of Molecular Biology for Endemic Diseases, Department of Biochemistry and Molecular Biology,
Simayi D, Guan Y
doaj  

A histidine‐rich extension of the mitochondrial F0 subunit ATP6 from the ice worm Mesenchytraeus solifugus increases ATP synthase activity in bacteria

open access: yesFEBS Letters, EarlyView.
The glacier ice worm Mesenchytraeus solifugus survives year‐round at 0 °C. Its ATP6 subunit, which forms a regulatory component of the proton pore in mitochondrial ATP synthase, has a carboxy‐terminal extension not found in any other organism examined to date. Here, we show that fusion of this extension to the homologous AtpB protein in E. coli results
Truman Dunkley   +2 more
wiley   +1 more source

4D Liquid-phase Electron Microscopy of Ferritin by Brownian Single Particle Analysis [PDF]

open access: yesarXiv, 2019
Protein function and activity are a consequence of its three-dimensional structure. Single particle analysis of cryogenic electron micrographs has radically changed structural biology allowing atomic reconstruction of almost any type of proteins.
arxiv  

Microplastic abundance and its correlation with potential oyster pathogen Vibrio splendidus along coastal Georgia [PDF]

open access: yes, 2020
Microplastics have been introduced into the marine environment either directly from runoff or through the weathering of larger plastic debris. Currently, there was not widespread data on the distribution of microplastic particles in marine environments ...
Smith, Mishana
core   +1 more source

The molecular biology, biochemistry, and physiology of human steroidogenesis and its disorders.

open access: yesEndocrine reviews, 2011
Steroidogenesis entails processes by which cholesterol is converted to biologically active steroid hormones. Whereas most endocrine texts discuss adrenal, ovarian, testicular, placental, and other steroidogenic processes in a gland-specific fashion ...
W. Miller, R. Auchus
semanticscholar   +1 more source

Elucidation of interface interactions between a dehydratase domain and an acyl carrier protein in cremimycin polyketide synthase

open access: yesFEBS Letters, EarlyView.
In modular polyketide synthases, the dehydratase (DH) domain catalyzes the dehydration reaction of the β‐hydroxyacyl unit attached to the cognate acyl carrier protein (ACP) domain. However, it is unclear how DH interacts with ACP during the reaction. In this study, we identified DH–ACP interface residues, providing the first detailed insights into DH ...
Kaede Kotagiri   +8 more
wiley   +1 more source

Metabolomic associations of impaired awareness of hypoglycaemia in type 1 diabetes

open access: yesScientific Reports
This study investigates impaired awareness of hypoglycaemia (IAH), a complication of insulin therapy affecting 20–40% of individuals with type 1 diabetes.
R. D. M. Varkevisser   +7 more
doaj   +1 more source

Effect of dietary supplementation of some antioxidants on growth performance, carcass composition and breast meat characteristics in quails reared under heat stress

open access: yesCzech Journal of Animal Science, 2010
This research investigates the effects of adding vitamin E, vitamin C, vitamin E+C, and alpha lipoic acid to feed rations for Japanese quails (Coturnix coturnix japonica) exposed to heat stress.
H. Imik   +4 more
doaj   +1 more source

Functional variation among LPMOs revealed by the inhibitory effects of cyanide and buffer ions

open access: yesFEBS Letters, EarlyView.
This study addresses the inhibition of lytic polysaccharide monooxygenases (LPMOs) by cyanide and explains how and why the magnitude of observed inhibitory effects depends on the way LPMO reactions are setup and on the type of LPMO. Enzymes known as lytic polysaccharide monooxygenases (LPMOs) are mono‐copper polysaccharide‐degrading peroxygenases that ...
Ole Golten   +10 more
wiley   +1 more source

Review of the genus Microchilus Blanchard (Coleoptera: Scarabaeidae: Rutelinae: Geniatini) [PDF]

open access: yes, 2009
The Brazilian scarab beetle genus Microchilus Blanchard (Rutelinae: Geniatini) is reviewed. Based on examination of type specimens, Microchilus beckeri Martínez is transferred to the genus Leucothyreus becoming L.
Jameson, Mary Liz
core  

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