Results 141 to 150 of about 15,925,070 (360)
Design and construction of a new Drosophila species, D.synthetica, by synthetic regulatory evolution [PDF]
, 2011 Here, I merge the principles of synthetic biology^1,2^ and regulatory evolution^3-11^ to create a new species^12-15^ with a minimal set of known elements.
Eduardo Moreno
core +1 more source
Jurnal BIOEDUIN, 2019 This study aims to determine the drawing based modeling implementation aid eBeam Capture in stimulating the Microscopic Representation of Prospective Biology Teachers in the Digital Era.
Tomi Hidayat +3 more
doaj +1 more source
Simultaneous lineage tracing and cell-type identification using CRISPR/Cas9-induced genetic scars
Nature Biotechnology, 2018 A key goal of developmental biology is to understand how a single cell is transformed into a full-grown organism comprising many different cell types.
B. Spanjaard +6 more
semanticscholar +1 more source
FEBS Letters, EarlyView.Three‐dimensional (3D) biological systems have become key tools in lymphoma research, offering reliable in vitro and ex vivo platforms to explore pathogenesis and support precision medicine. This review highlights current 3D non‐Hodgkin lymphoma models, detailing their features, advantages, and limitations, and provides a broad perspective on future ...
Carla Faria +3 more
wiley +1 more source
From omics to AI—mapping the pathogenic pathways in type 2 diabetes
FEBS Letters, EarlyView.Integrating multi‐omics data with AI‐based modelling (unsupervised and supervised machine learning) identify optimal patient clusters, informing AI‐driven accurate risk stratification. Digital twins simulate individual trajectories in real time, guiding precision medicine by matching patients to targeted therapies.
Siobhán O'Sullivan +2 more
wiley +1 more source
DC-SIGN, a C-type lectin on dendritic cells that unveils many aspects of dendritic cell biology [PDF]
, 2002 Teunis B. H. Geijtenbeek +2 more
openalex +1 more source
Intersection of biology and therapeutics: type 2 targeted therapeutics for adult asthma
The Lancet, 2020 M. Peters, S. Wenzel
semanticscholar +1 more source
The anabolic steroid stanozolol is a potent inhibitor of human MutT homolog 1
FEBS Letters, EarlyView.MutT homolog 1 (MTH1) is a member of the NUDIX superfamily of enzymes and is an anticancer drug target. We show that stanozolol (Stz), an anabolic steroid, is an unexpected nanomolar inhibitor of MTH1. The X‐ray crystal structure of the human MTH1–Stz complex reveals a unique binding scaffold that could be utilized for future inhibitor development ...
Emma Scaletti Hutchinson +7 more
wiley +1 more source
Forensic DNA Typing: Biology and Technology behind STR Markers [PDF]
, 2002 Lee Chatfield
openalex +1 more source
FEBS Letters, EarlyView.Tuberculosis remains a global health challenge and new therapeutic targets are required. Here, we characterized SseA, a sulfurtransferase from Mycobacterium tuberculosis involved in macrophage infection, and its interaction with the newly identified protein SufEMtb that activates SseA enzymatic activity.
Giulia Di Napoli +10 more
wiley +1 more source