Results 141 to 150 of about 16,440,357 (384)

PENGEMBANGAN MEDIA PEMBELAJARAN VIDEO ANIMASI STOP MOTION UNTUK PEMBELAJARAN BIOLOGI DENGAN APLIKASI PICPAC

open access: yesJurnal BIOEDUIN, 2018
Based on the observation, the problem in Biology learning is the students are less enthusiastic about Biology lesson because of too many theories and topics that must be memorized and remembered so its decrease their learning interest.
Sri Maryanti, Dede trie Kurniawan
doaj   +1 more source

Integration of circadian and hypoxia signaling via non‐canonical heterodimerization

open access: yesFEBS Letters, EarlyView.
CLOCK, BMAL1, and HIFs are basic helix‐loop‐helix and Per‐Arnt‐Sim domain (bHLH‐PAS) proteins, which function as transcription factors. bHLH‐PAS proteins are designated in two classes. Many class I proteins are regulated by environmental signals via their PAS domains, but such signals have not been identified for all.
Sicong Wang, Katja A. Lamia
wiley   +1 more source

Structural biology of Helicobacter pylori type IV secretion system [PDF]

open access: gold, 2006
Alessandro Angelini   +6 more
openalex   +1 more source

Substrate specificity of Burkholderia pseudomallei multidrug transporters is influenced by the hydrophilic patch in the substrate‐binding pocket

open access: yesFEBS Letters, EarlyView.
Multidrug transporters BpeB and BpeF from the Gram‐negative pathogen Burkholderia pseudomallei have a hydrophilic patch in their substrate‐binding pocket. Drug susceptibility tests and growth curve analyses using an Escherichia coli recombinant expression system revealed that the hydrophilic patches of BpeB and BpeF are involved in the substrate ...
Ui Okada, Satoshi Murakami
wiley   +1 more source

The structural and molecular biology of type III galactosemia [PDF]

open access: yesIUBMB Life (International Union of Biochemistry and Molecular Biology: Life), 2006
Type III galactosemia is a genetic disease caused by mutations in the gene encoding UDP-galactose 4-epimerase. A variety of different point mutations located throughout the gene can be responsible. The main, disease-causing effects of these mutations appear to be a reduction in the catalytic rate constant (kcat) and an increase in the proteolytic ...
openaire   +3 more sources

Biology and Bias in Cell Type-Specific RNAseq of Nucleus Accumbens Medium Spiny Neurons [PDF]

open access: gold, 2018
Hope Kronman   +8 more
openalex   +1 more source

Systems Biology Approaches Reveal Potential Phenotype-Modifier Genes in Neurofibromatosis Type 1 [PDF]

open access: gold, 2020
Thayne Woycinck Kowalski   +4 more
openalex   +1 more source

Function‐driven design of a surrogate interleukin‐2 receptor ligand

open access: yesFEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang   +9 more
wiley   +1 more source

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