Results 171 to 180 of about 15,878,608 (386)

Non-negativity preserving numerical algorithms for stochastic differential equations [PDF]

open access: yes, 2005
Construction of splitting-step methods and properties of related non-negativity and boundary preserving numerical algorithms for solving stochastic differential equations (SDEs) of Ito-type are discussed.
Moro, Esteban, Schurz, Henri
core   +1 more source

Type of prey influences biology and consumption rate of Orius insidiosus (Say) (Hemiptera, Anthocoridae) [PDF]

open access: gold, 2002
S. M. Mendes   +3 more
openalex   +1 more source

The solution supramolecular structure of α2 → 8 polysialic acid suggests a structural cause for its low immunogenicity

open access: yesFEBS Letters, EarlyView.
α2 → 8 polysialic acid elicits poor immunogenicity. Small‐angle scattering shows a supramolecular structure with parallel‐chain binding, although in different forms at μm and mm calcium. The major histocompatibility complex requires molecular weights around 2000 Da to produce antibodies, and 2000 Da polysialic oligomers will bind in these structures ...
Kenneth A. Rubinson
wiley   +1 more source

Elucidation of time-dependent systems biology cell response patterns with time course network enrichment [PDF]

open access: yesarXiv, 2017
Advances in OMICS technologies emerged both massive expression data sets and huge networks modelling the molecular interplay of genes, RNAs, proteins and metabolites. Network enrichment methods combine these two data types to extract subnetwork responses from case/control setups.
arxiv  

The k-NN algorithm for compositional data: a revised approach with and without zero values present [PDF]

open access: yes, 2014
In compositional data, an observation is a vector with non-negative components which sum to a constant, typically 1. Data of this type arise in many areas, such as geology, archaeology, biology, economics and political science among others.
Tsagris, Michail
core   +1 more source

Refining the NaV1.7 pharmacophore of a class of venom‐derived peptide inhibitors via a combination of in silico screening and rational engineering

open access: yesFEBS Letters, EarlyView.
Venom peptides have shown promise in treating pain. Our study uses computer screening to identify a peptide that targets a sodium channel (NaV1.7) linked to chronic pain. We produced the peptide in the laboratory and refined its design, advancing the search for innovative pain therapies.
Gagan Sharma   +8 more
wiley   +1 more source

A New Hierarchical Redundancy Eliminated Tree Augmented Naive Bayes Classifier for Coping with Gene Ontology-based Features [PDF]

open access: yes, 2016
The Tree Augmented Naive Bayes classifier is a type of probabilistic graphical model that can represent some feature dependencies. In this work, we propose a Hierarchical Redundancy Eliminated Tree Augmented Naive Bayes (HRE-TAN) algorithm, which ...
Freitas, Alex A., Wan, Cen
core   +2 more sources

The power of microRNA regulation—insights into immunity and metabolism

open access: yesFEBS Letters, EarlyView.
MicroRNAs are emerging as crucial regulators at the intersection of metabolism and immunity. This review examines how miRNAs coordinate glucose and lipid metabolism while simultaneously modulating T‐cell development and immune responses. Moreover, it highlights how cutting‐edge artificial intelligence applications can identify miRNA biomarkers ...
Stefania Oliveto   +2 more
wiley   +1 more source

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