Results 191 to 200 of about 15,878,608 (386)

Subpar reporting of pre‐analytical variables in RNA‐focused blood plasma studies

Molecular Oncology, EarlyView.
Pre‐analytical variables strongly influence the analysis of extracellular RNA (cell‐free RNA; exRNA) derived from blood plasma. Their reporting is essential to allow interpretation and replication of results. By evaluating 200 exRNA studies, we pinpoint a lack of reporting pre‐analytical variables associated with blood collection, plasma preparation ...
Céleste Van Der Schueren, Philippe Decruyenaere, Francisco Avila Cobos, Johanna Bult, Jill Deleu, Laudonia Lidia Dipalo, Hetty Hilde Helsmoortel, Eva Hulstaert, Annelien Morlion, Elena Ramos Varas, Kathleen Schoofs, Wim Trypsteen, Eveline Vanden Eynde, Hanne Van Droogenbroeck, Kimberly Verniers, Jo Vandesompele, Anneleen Decock   +16 more
wiley   +1 more source

Mathematical Modeling Highlights the Complex Role of AKT in TRAIL-Induced Apoptosis of Colorectal Carcinoma Cells

iScience, 2019
Summary: Protein kinase B/AKT is a highly connected protein involved in a range of signaling pathways. Although it is known to regulate several proteins in the apoptotic pathway, its system-level effects remain poorly understood.
Matthew W. Anderson, Joanna J. Moss, Robert Szalai, Jon D. Lane   +3 more
doaj  

Mechanisms Underlying Novel Roles of Rpt-1 in Long-term Synaptic Plasticity [PDF]

Synaptic plasticity refers to the changing of synaptic strength and underlies the ability of the nervous system to store information. A cellular process of increasing synaptic strength is long-term potentiation (LTP) which is thought to be critical for ...
Timm, Logan
core   +1 more source

Effect of nestbox type on occupancy and breeding biology of Tree Sparrows Passer montanus in central Spain [PDF]

, 2008
Vicente García‐Navas, Luis G. Arroyo, Juan José Sanz, Mario Dı́az   +3 more
openalex   +1 more source

Identification of functional and diverse circulating cancer‐associated fibroblasts in metastatic castration‐naïve prostate cancer patients

Molecular Oncology, EarlyView.
Cancer‐associated fibroblasts (CAFs) promote cancer growth, invasion (metastasis), and drug resistance. Here, we identified functional and diverse circulating CAFs (cCAFs) in patients with metastatic prostate cancer (mPCa). cCAFs were found in higher numbers and were functional and diverse in mPCa patients versus healthy individuals, suggesting their ...
Richell Booijink, Leon W. M. M. Terstappen, Eshwari Dathathri, Khrystany Isebia, Jaco Kraan, John Martens, Ruchi Bansal   +6 more
wiley   +1 more source

EFFECT OF DIFFERENT FOOD TYPES ON THE BIOLOGY, FECUNDITY AND LIFE TABLE PARAMETERS OF THE STORED GRAIN MITE GOHIERIA FUSCA (OUD.) (ACARI : ASTIGMATA : LAPIDOPHORIDAE) [PDF]

, 2010
Hassan Ali Taha, HANNA I. MAHMOUD, Moustafa I. Hassan, NAHED R. OMAR, Heba M. Nasr   +4 more
openalex   +1 more source

Surfaceome: a new era in the discovery of immune evasion mechanisms of circulating tumor cells

Molecular Oncology, EarlyView.
In the era of immunotherapies, many patients either do not respond or eventually develop resistance. We propose to pave the way for proteomic analysis of surface‐expressed proteins called surfaceome, of circulating tumor cells. This approach seeks to identify immune evasion mechanisms and discover potential therapeutic targets. Circulating tumor cells (
Doryan Masmoudi, Jérome Vialaret, Christophe Hirtz, Catherine Alix‐Panabières   +3 more
wiley   +1 more source

Clinical applications of next‐generation sequencing‐based ctDNA analyses in breast cancer: defining treatment targets and dynamic changes during disease progression

Molecular Oncology, EarlyView.
Circulating tumor DNA (ctDNA) offers a possibility for different applications in early and late stage breast cancer management. In early breast cancer tumor informed approaches are increasingly used for detecting molecular residual disease (MRD) and early recurrence. In advanced stage, ctDNA provides a possibility for monitoring disease progression and
Eva Valentina Klocker, Samantha Hasenleithner, Rupert Bartsch, Simon P. Gampenrieder, Daniel Egle, Christian F. Singer, Gabriel Rinnerthaler, Michael Hubalek, Katja Schmitz, Zsuzsanna Bago‐Horvath, Andreas Petzer, Sonja Heibl, Ellen Heitzer, Marija Balic, Michael Gnant   +14 more
wiley   +1 more source

Perceived difficulty levels of basic concepts in biology by teachers in senior schools in Ogbomosho, Nigeria

Assimilation
Over the years, many factors have been visible that lead to unimpressive performance in biology. One of the factors includes ineffectiveness and inefficiency of biology teachers which results from the difficulties faced with some biology concepts.
Oluseye Adegboye Alawonde, Akindeyi Luwoye, Abiola Tawa Ahmed, Mulkah Adebisi Ahmed, Ahmatullahi Folakemi Abimbola   +4 more
doaj   +1 more source

Large Language Models in Plant Biology [PDF]

arXiv
Large Language Models (LLMs), such as ChatGPT, have taken the world by storm and have passed certain forms of the Turing test. However, LLMs are not limited to human language and analyze sequential data, such as DNA, protein, and gene expression.
arxiv