Results 1 to 10 of about 1,740,047 (309)

Correlation between stem cell molecular phenotype and atherosclerotic plaque neointima formation and analysis of stem cell signal pathways [PDF]

Frontiers in Cell and Developmental Biology, 2023
Vascular stem cells exist in the three-layer structure of blood vessel walls and play an indispensable role in angiogenesis under physiological conditions and vascular remodeling under pathological conditions.
Chuanxin Shi, Kefan Zhang, Zhenyu Zhao, Yifan Wang, Haozhe Xu, Wei Wei   +5 more
doaj   +2 more sources

Data characterizing the ZMIZ1 molecular phenotype of multiple sclerosis [PDF]

Data in Brief, 2017
The data presented in this article are related to the research article entitled “The autoimmune risk gene ZMIZ1 is a vitamin D responsived marker of a molecular phenotype of multiple sclerosis” Fewings et al. (2017) [1]. Here we identify the set of genes
N. Fewings, P.N. Gatt, F.C. McKay, G.P. Parnell, S.D. Schibeci, J. Edwards, M.A. Basuki, A. Goldinger, M.J. Fabis-Pedrini, A.G. Kermode, C.P. Manrique, J.L. McCauley, D. Nickles, S.E. Baranzini, T. Burke, S. Vucic, G.J. Stewart, D.R. Booth   +17 more
doaj   +2 more sources

Pattern of molecular phenotypes of breast carcinomas using immunohistochemistry in a district hospital in Nigeria

Nigerian Journal of Medicine, 2021
Background: Cancer of the breast is the most common organ-specific cancer, affecting women worldwide with disproportionately higher mortality seen among women of Africa ancestry.
Kevin Nwabueze Ezike, Solomon Raphael, Damian Ikechukwu Okonkwo, Ijeoma Ahunna Okwudire-Ijeh   +3 more
doaj   +1 more source

Depiction of Aging-Based Molecular Phenotypes With Diverse Clinical Prognosis and Immunological Features in Gastric Cancer

Frontiers in Medicine, 2022
ObjectiveAging acts as a dominating risk factor for human cancers. Herein, we systematically dissected the features of transcriptional aging-relevant genes in gastric cancer from multiple perspectives.MethodsBased on the transcriptome profiling of ...
Fang He, Huan Ding, Yang Zhou, Yuanzhen Wang, Juan Xie, Shaoqi Yang, Yongzhao Zhu   +6 more
doaj   +1 more source

Interpretation According to Clone-Specific PD-L1 Cutoffs Reveals Better Concordance in Muscle-Invasive Urothelial Carcinoma

Diagnostics, 2021
Because immune checkpoint inhibitors have been approved for treating advanced urothelial carcinoma (UC), programmed death-ligand 1 (PD-L1) immunohistochemistry (IHC) assays have been widely used as companion or complementary diagnostic tests for ...
Tzu-Hao Huang, Wei Cheng, Yeh-Han Wang
doaj   +1 more source

Cytokine expression patterns in hospitalized children with Bordetella pertussis, Rhinovirus or co-infection

Scientific Reports, 2021
Mechanisms of interaction between Bordetella pertussis and other viral agents are yet to be fully explored. We studied the inflammatory cytokine expression patterns among children with both viral-bacterial infections.
Elisabetta Pandolfi, Nadia Panera, Anna Alisi, Emanuela Carloni, Luisa Russo, Ilaria Campagna, Caterina Rizzo, Carlo Concato, Giulia Linardos, Livia Piccioni, Sally Jackson, Alberto Villani, Fabio Midulla, Alberto E. Tozzi   +13 more
doaj   +1 more source

Molecular T2 asthma phenotypes are stable but heterogeneous: the usefulness of periostin for endotyping

Frontiers in Allergy, 2023
BackgroundThe stability of molecular T2/non-T2 phenotypes remains uncertain. The objectives of this study were to assess the stability of these phenotypes and the correlation between serum periostin and asthma T2 phenotypes and endotypes ...
Irina Bobolea, Daniela Guillén-Vera, Natividad De las Cuevas-Moreno, Diego Blanco García-Granero, David Loli-Ausejo, Carlos Melero-Moreno   +5 more
doaj   +1 more source

Molecular Phenotyping of White Striping and Wooden Breast Myopathies in Chicken

Frontiers in Physiology, 2020
The White Striping (WS) and Wooden Breast (WB) defects are two myopathic syndromes whose occurrence has recently increased in modern fast-growing broilers.
Christophe Praud, Justine Jimenez, Eva Pampouille, Nathalie Couroussé, Estelle Godet, Elisabeth Le Bihan-Duval, Cecile Berri   +6 more
doaj   +1 more source

Tendinosis develops from age- and oxygen tension-dependent modulation of Rac1 activity. [PDF]

, 2019
Age-related tendon degeneration (tendinosis) is characterized by a phenotypic change in which tenocytes display characteristics of fibrochondrocytes and mineralized fibrochondrocytes.
Edwards, Richard W., Maltenfort, Mitchell G., McBeath, Rowena, O\u27Hara, Brian J., Osterman, A. Lee, Parks, Susan M., Shapiro, Irving M., Steplewski, Andrzej   +7 more
core   +2 more sources

Targeted mutagenesis using CRISPR-Cas9 in the chelicerate herbivore Tetranychus urticae [PDF]

, 2020
The use of CRISPR-Cas9 has revolutionized functional genetic work in many organisms, including more and more insect species. However, successful gene editing or genetic transformation has not yet been reported for chelicerates, the second largest group ...
Dermauw, Wannes, Jonckheere, Wim, Livadaras, Ioannis, Riga, Maria, Van Leeuwen, Thomas, Vontas, John   +5 more
core   +1 more source