Results 201 to 210 of about 14,138,795 (349)

Cytomegalovirus infection is common in prostate cancer and antiviral therapies inhibit progression in disease models

Molecular Oncology, EarlyView.
Human cytomegalovirus infection is common in normal prostate epithelium, prostate tumor tissue, and prostate cancer cell lines. CMV promotes cell survival, proliferation, and androgen receptor signaling. Anti‐CMV pharmaceutical compounds in clinical use inhibited cell expansion in prostate cancer models in vitro and in vivo, motivating investigation ...
Johanna Classon, Moa Stenudd, Margherita Zamboni, Kanar Alkass, Carl‐Johan Eriksson, Lars Pedersen, Alrik Schörling, Anna Thoss, Anders Bergh, Pernilla Wikström, Hans‐Olov Adami, Henrik Toft Sørensen, Henrik Druid, Jonas Frisén   +13 more
wiley   +1 more source

Predicting chromatin conformation contact maps. [PDF]

PLoS One
Min A, Schreiber J, Kundaje A, Noble WS.
europepmc   +1 more source

Telomere biology and metabolic disorders: the role of insulin resistance and type 2 diabetes

, 2020
Е. N. Dudinskaya, О. Н. Ткачева, Н. В. Браилова, И. Д. Стражеско, Marina V. Shestakova   +4 more
openalex   +2 more sources

Integrative miRNOMe profiling reveals the miR‐195‐5p–CHEK1 axis and its impact on luminal breast cancer outcomes

Molecular Oncology, EarlyView.
In luminal (ER+) breast carcinoma (BC), miRNA profiling identified miR‐195‐5p as a key regulator of proliferation that targets CHEK1, CDC25A, and CCNE1. High CHEK1 expression correlates with worse relapse‐free survival after chemotherapy, especially in patients with luminal A subtype.
Veronika Boušková, Marie Ehrlichová, Alžběta Spálenková, Ivona Krus, Simona Šůsová, Viktor Hlaváč, Vlasta Němcová, Renata Koževnikovová, Markéta Trnková, David Vrána, Jiří Gatěk, Kateřina Kopečková, Marcela Mrhalová, Soňa Měšťáková, Pavel Souček   +14 more
wiley   +1 more source

Sustainable Production of Ginsenosides: Advances in Biosynthesis and Metabolic Engineering. [PDF]

Plants (Basel)
Xue Y, Zhang R, Li T, Deng Q, Luo W, Chang R, Zeng D, Tan J, Sun T, Liu YG, Xiang Y, Zhu Q, Chai N.   +12 more
europepmc   +1 more source

Editorial Overview: “Islet Biology in Type 2 Diabetes”

Journal of Molecular Biology, 2020
Gaisano, Herbert Y., Jonas, Jean-Christophe, Gloyn, Anna L.   +2 more
openaire   +4 more sources

An introductory overview of new article type “Opinion” in Plant Nano Biology

, 2023
Durgesh Kumar Tripathi
openalex   +1 more source

Association of high‐dose radioactive iodine therapy with PPM1D‐mutated clonal hematopoiesis in older individuals

Molecular Oncology, EarlyView.
In thyroid cancer patients, high‐dose (≥7.4 GBq) radioactive iodine therapy (RAIT) was associated with a higher prevalence of clonal hematopoiesis (variant allele frequency >2%) in individuals aged ≥50 years (OR = 2.44). In silico analyses showed that truncating PPM1D mutations conferred a selective advantage under these conditions.
Jaeryuk Kim, Sungwoo Bae, Jaeyong Choi, Sun‐Wha Im, Bukyoung Cha, Gyeongseo Jung, Sun Wook Cho, Eul‐Ju Seo, Young Ah Lee, Jin Chul Paeng, Young Joo Park, Jong‐Il Kim   +11 more
wiley   +1 more source

50 Years Journal of Mathematical Biology. [PDF]

J Math Biol
Hillen T, Marciniak-Czochra A.
europepmc   +1 more source

Lipid droplets and liver disease: from basic biology to clinical implications

Nature Reviews Gastroenterology &Hepatology, 2017
N. Gluchowski, Michel Becuwe, T. Walther, Robert V Farese   +3 more
semanticscholar   +1 more source