Results 211 to 220 of about 16,440,357 (384)

Lipid droplets and liver disease: from basic biology to clinical implications

open access: yesNature Reviews Gastroenterology &Hepatology, 2017
N. Gluchowski   +3 more
semanticscholar   +1 more source

A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression

open access: yesMolecular Oncology, EarlyView.
Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak   +8 more
wiley   +1 more source

HIV-1 derived oligonucleotides induce a type I IFN/STING dependent immune suppression reversible by targeting IFNARI. [PDF]

open access: yesPLoS Pathog
Svanberg C   +7 more
europepmc   +1 more source

Brain insulin resistance in type 2 diabetes and Alzheimer disease: concepts and conundrums

open access: yesNature Reviews Neurology, 2018
S. Arnold   +11 more
semanticscholar   +1 more source

Adaptaquin is selectively toxic to glioma stem cells through disruption of iron and cholesterol metabolism

open access: yesMolecular Oncology, EarlyView.
Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié   +16 more
wiley   +1 more source

ASTRA: a comprehensive resource of stress-induced transcriptional activity in human cell lines. [PDF]

open access: yesNucleic Acids Res
Tsifintaris M   +9 more
europepmc   +1 more source

Comparative biology and production costs of Podisus nigrispinus (Hemiptera: Pentatomidae) when fed different types of prey

open access: bronze, 2011
Sérgio Antônio De Bortoli   +4 more
openalex   +2 more sources

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