Results 241 to 250 of about 3,872,661 (296)

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

open access: yesFEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj   +3 more
wiley   +1 more source

SIRT4 positively regulates autophagy via ULK1, but independently of HDAC6 and OPA1

open access: yesFEBS Open Bio, EarlyView.
Cells expressing SIRT4 (H161Y), a catalytically inactive mutant of the sirtuin SIRT4, fail to upregulate LC3B‐II and exhibit a reduced autophagic flux under stress conditions. Interestingly, SIRT4(H161Y) promotes phosphorylation of ULK1 at S638 and S758 that are associated with inhibition of autophagy initiation.
Isabell Lehmkuhl   +13 more
wiley   +1 more source

OmniBio: an easy-to-use web app for kinetic growth parameter calculation from microplate reader data. [PDF]

open access: yesBioinform Adv
Dehnhardt-Amengual S   +5 more
europepmc   +1 more source

Integrated transcriptome and single-cell sequencing analysis identify blood-pancreas shared lncRNA biomarkers in new-onset T2DM. [PDF]

open access: yesPLoS One
Wang Y   +14 more
europepmc   +1 more source

A Reference-Free Algorithm Discovers Regulation in the Plant Transcriptome. [PDF]

open access: yesPlant Direct
Meyer E   +6 more
europepmc   +1 more source

Biology, structure and mechanism of P-type ATPases

Nature Reviews Molecular Cell Biology, 2004
P-type ATPases are ion pumps that carry out many fundamental processes in biology and medicine, ranging from the generation of membrane potential to muscle contraction and the removal of toxic ions from cells. Making use of the energy stored in ATP, they transport specific ions across the cell membrane against a concentration gradient.
Werner Kühlbrandt
openaire   +4 more sources

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