Results 311 to 320 of about 15,925,070 (360)

Machine learning for identifying liver and pancreas cancers through comprehensive serum glycopeptide spectra analysis: a case‐control study

Molecular Oncology, EarlyView.
This study presents a novel AI‐based diagnostic approach—comprehensive serum glycopeptide spectra analysis (CSGSA)—that integrates tumor markers and enriched glycopeptides from serum. Using a neural network model, this method accurately distinguishes liver and pancreatic cancers from healthy individuals.
Motoyuki Kohjima, Yuko Takami, Ken Kawabe, Kazuhiro Tanabe, Chihiro Hayashi, Mikio Mikami, Tetsuya Kusumoto   +6 more
wiley   +1 more source

H- and m-channel overexpression promotes seizure-like events by impairing the ability of inhibitory neurons to process correlated inputs. [PDF]

PLoS Comput Biol
Rich S, Valiante TA, Lefebvre J.
europepmc   +1 more source

Exploring the role of cyclin D1 in the pathogenesis of multiple myeloma beyond cell cycle regulation

Molecular Oncology, EarlyView.
Cyclin D1 overexpression altered the cell adhesion pathway, while cyclin D2 upregulation had less impact on pathway enrichment analysis. Multiple myeloma (MM) patients with cyclin D1 overexpression showed reduced CD56 expression and increased circulating tumor cells (CTC) levels, suggesting that cyclin D1 may contribute to MM cell dissemination ...
Ignacio J. Cardona‐Benavides, Sara Cristobal‐Vargas, Cristina De Ramón, Elizabeta A. Rojas, Irena Misiewicz‐Krzeminska, Isabel Isidro, José Juan Pérez, Bruno Paiva, Noemi Puig, Miguel Alcoceba, María‐Victoria Mateos, Luis A. Corchete, Myriam Cuadrado, Norma C. Gutiérrez   +13 more
wiley   +1 more source

Territorial song frequency does not signal body size in a song-learning passerine. [PDF]

Sci Rep
Zampa L, Szymański P, Łosak K, Osiejuk TS.   +3 more
europepmc   +1 more source

Comprehensive profiling of lncRNAs and mRNAs enriched in small extracellular vesicles for early noninvasive detection of colorectal cancer: diagnostic panel assembly and extensive validation

Molecular Oncology, EarlyView.
Small extracellular vesicles are a promising source of diagnostic molecules. We conducted a comprehensive study, including transcriptome profiling and RT‐qPCR validation on large cohorts of samples. Diagnostic panels enabling sensitive detection of colorectal cancer and precancerous lesions were established. Some molecules were differentially expressed
Petra Vychytilova‐Faltejskova, Marketa Pavlikova, Lucie Pifkova, Robin Jugas, Tana Machackova, Lenka Radova, Milana Sachlova, Renata Bartosova, Tetiana Samoilenko, Zuzana Feckova, Jana Orlickova, Erika Slamova, Elleni Ponechal Michu, Dagmar Al Tukmachi, Michaela Ruckova, Martina Vodinska, Jan Kotoucek, Tina Catela Ivkovic, Marie Boudna, Lucia Bohovicova, Teodor Stanek, Jana Halamkova, Martin Svoboda, Vladimir Prochazka, Tomas Grolich, Zdenek Kala, Ondrej Slaby   +26 more
wiley   +1 more source

Subtypes and proliferation patterns of small intestine neuroendocrine tumors revealed by single-cell RNA sequencing. [PDF]

Elife
Somech E, Halder D, Spitzer A, Barbolin C, Tyler M, Halperin R, Biton M, Tirosh A, Tirosh I.   +8 more
europepmc   +1 more source

Doublesex and GATAβ4 synergistically regulate the sex-dimorphic expression of storage protein 1 in Bombyx mori. [PDF]

PLoS Genet
Yan J, Dong H, Tian T, Xiao C, Sun Y, Gong J, Xia Q, Hou Y.   +7 more
europepmc   +1 more source

The genus <i>Aerophilus</i> Szépligeti, 1902 (Hymenoptera, Braconidae, Agathidinae) in China. [PDF]

Biodivers Data J
Wu Q, Tang P, Fang Y, van Achterberg C, Chen XX.   +4 more
europepmc   +1 more source

Correction to: The Silverjaw Minnow, Ericymba buccata: An Extraordinary Lateral Line System and its Contribution to Prey Detection. [PDF]

Integr Comp Biol
europepmc   +1 more source

Complexity of schistosome vector bulinine snails in Kenya: Insights from nuclear genome size variation, complete mitochondrial genome sequence, and morphometric analysis. [PDF]

PLoS Negl Trop Dis
Zhang SM, Adema CM, Habib MR, Lekired A, Posavi M, Laidemitt MR, Maina GM, Mwangi IN, Kinuthia JM, Mutuku MW, Loker ES.   +10 more
europepmc   +1 more source