Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla +10 more
wiley +1 more source
Abscisic acid at the crossroad of abiotic stress responses and plant-microbe interactions. [PDF]
Makris A +3 more
europepmc +1 more source
Decoding the distinct immune landscape and possible regulatory mechanisms of autoimmune hepatitis through integrated single-cell and bulk RNA sequencing. [PDF]
Chi G, Che Y, Pei J, Li X, Wang J.
europepmc +1 more source
Inferring pathway activity from single-cell and spatial transcriptomics data with PaaSc. [PDF]
Liao X +5 more
europepmc +1 more source
Genetic variation shapes the chromatin accessibility landscape and transcriptional responses in mouse adipose tissue. [PDF]
Mononen J +6 more
europepmc +1 more source
Inter-brain ERPs alignment during a joint Simon task: An EEG hyperscanning study. [PDF]
Miti F +5 more
europepmc +1 more source
Gut microbiota and metabolites in lipid metabolism and intramuscular fat deposition: mechanisms and implications for meat quality. [PDF]
Song X, Jin C, Wu R, Wang Y, Wang X.
europepmc +1 more source

