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Molecular biology of human immunodeficiency virus Type-1

Transfusion Science, 1996
Tremendous progress has been made in our understanding of the multiplication and pathogenesis of the human immunodeficiency virus, the causative agent of acquired immunodeficiency syndrome (AIDS). To block virus multiplication several targets in the life cycle of the virus have already been identified for which antiviral drugs can be developed and gene
Joshi, S., Joshi, Rajiv L
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The structural and molecular biology of type IV galactosemia

Biochimie, 2021
Type IV galactosemia is a recently discovered inherited metabolic disease. It is caused by mutations in the GALM gene which result in reduced activity of the enzyme galactose mutarotase. This enzyme catalyses the interconversion of the α- and β-anomers of d-galactose and some other monosaccharides.
Samantha Banford, David J. Timson
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Molecular biology and pathology of type VII collagen*

Experimental Dermatology, 1992
Abstract Type VII collagen is a genetically distinct member of the collagen family of proteins. Type VII collagen has been shown to be the major component of anchoring fibrils, attachment complexes which secure the cutaneous basement membrance of the skin to the underlying dermis. Understanding of the structure of type VII collagen has been advanced by
J, Uitto   +2 more
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Biology, structure and mechanism of P-type ATPases

Nature Reviews Molecular Cell Biology, 2004
P-type ATPases are ion pumps that carry out many fundamental processes in biology and medicine, ranging from the generation of membrane potential to muscle contraction and the removal of toxic ions from cells. Making use of the energy stored in ATP, they transport specific ions across the cell membrane against a concentration gradient.
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The structural biology of type I viral membrane fusion

Nature Reviews Molecular Cell Biology, 2003
The fusion of viral membranes with target-cell membranes is an essential step in the entry of enveloped viruses into cells, and recent X-ray structures of paramyxoviral envelope proteins have provided new insights into protein-mediated plasma-membrane fusion.
Peter M, Colman, Michael C, Lawrence
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Behavior and Biology

The Journal of Cardiovascular Nursing, 2003
Type 2 diabetes mellitus (DM), characterized by insulin resistance and a beta-cell secretory defect, appears to result from a number of gene and environmental interactions. There are marked differences in the phenotypic expression of type 2 DM with individuals exhibiting varying levels of insulin resistance and impairments in insulin secretion.
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Molecular biology of the human immunodeficiency virus type 1

The FASEB Journal, 1991
The immunodeficiency virus type 1 is a complex retrovirus. In addition to genes that specify the proteins of the virus particle and the replicative enzymes common to all retroviruses, HIV‐1 specifies at least six additional proteins that regulate the virus life cycle. Two of these regulatory genes, tat
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HLA Typing From Serology to Molecular Biology

1997
During the last few years Histocompatibility Laboratories have started to use DNA techniques. There are many benefits to using such techniques. There is no need for antisera, which are becoming very difficult to obtain as many laboratories have stopped screening for HLA reagents and few laboratories have the technology to produce specific HLA ...
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