Results 161 to 170 of about 3,278,641 (315)

Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells

Molecular Oncology, EarlyView.
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son, Lily L. Remsing Rix, Bin Fang, Eric A. Welsh, Nicole V. Bremer, Valentina Foglizzo, Paola Roa, Nickole Sigcha‐Coello, Yi Liao, Eric B. Haura, Alexander Drilon, John M. Koomen, Emiliano Cocco, Uwe Rix   +13 more
wiley   +1 more source

Risk network analysis and simulation research in municipal engineering projects contracted by China in Saudi Arabia. [PDF]

Sci Rep
Alotaibi RTT.
europepmc   +1 more source

NUMERICAL ANALYSIS TO DESIGN HIGH TEMPERATURE HEAT EXCHANGER OF BETA TYPE STIRLING ENGINE IN 3-D COMBUSTION FIELD [PDF]

, 2011
S.H. Kang, H.J. Kim, D.H. Chung
openalex   +1 more source

Molecular characterisation of human penile carcinoma and generation of paired epithelial primary cell lines

Molecular Oncology, EarlyView.
Generation of two normal and tumour (cancerous) paired human cell lines using an established tissue culture technique and their characterisation is described. Cell lines were characterised at cellular, protein, chromosome and gene expression levels and for HPV status.
Simon Broad, Mahmood Hachim, Tom Bertin, Karolina Penderecka, Rifat Hamoudi, Saif Khan, Rui Henrique, Natalie Bergmoser, Manit Arya, Kalle Sipila, Matteo Vietri Rudan, Asif Muneer, Aamir Ahmed   +12 more
wiley   +1 more source

A Comparison of Randomizing Either One Eye or Both Eyes in Clinical Trials for Stargardt Disease Type 1. [PDF]

Ophthalmol Sci
Pas JAAH, Dhooge PPA, Li CHZ, Collin RWJ, Hoyng CB, IntHout J.   +5 more
europepmc   +1 more source

Design of an integrating type neutron dose monitor

, 2011
Hirokuni Yamanishi
openalex   +2 more sources

Methylation biomarkers can distinguish pleural mesothelioma from healthy pleura and other pleural pathologies

Molecular Oncology, EarlyView.
We developed and validated a DNA methylation–based biomarker panel to distinguish pleural mesothelioma from other pleural conditions. Using the IMPRESS technology, we translated this panel into a clinically applicable assay. The resulting two classifier models demonstrated excellent performance, achieving high AUC values and strong diagnostic accuracy.
Janah Vandenhoeck, Nele De Meulenaere, Thomas Vanpoucke, Joe Ibrahim, Dieter Peeters, Suresh Krishan Yogeswaran, Wen Wen, Paul Van Schil, Jeroen M. H. Hendriks, Jo Raskin, Jan van Meerbeeck, Guy Van Camp, Ken Op de Beeck   +12 more
wiley   +1 more source

Empirical aesthetics of bridges. [PDF]

PLoS One
Yang M, Damiano C, Gauvreau P, Walther DB.   +3 more
europepmc   +1 more source

Analysis and design of an elevated reinforced concrete water tank of the Intze type

, 1966
Balbir S. Sandhu
openalex   +1 more source

Wave Dissipating Effect of a Swash Plate Type Submerged Breakwater (SURF) and its Design Method

, 1991
Seizo Ueno, Akemi Sato, Masaya Kato, Takaaki UDA, Atsushi Omata   +4 more
openalex   +2 more sources