Results 251 to 260 of about 31,306,322 (385)

Implementation and effectiveness of an intervention to Prevent and Reduce Involuntary Treatment at Home (PRITAH) in people living with dementia: protocol for a hybrid design type 3 quasi-experimental study. [PDF]

BMC Geriatr
Ponstein K, Erkens PMG, van Breukelen GJP, Hamers JPH, Bleijlevens MHC.   +4 more
europepmc   +1 more source

Effects of Early Maturation of Brown Egg-Type Pullets, Flock Uniformity, Layer Protein Level, and Cage Design on Egg Production, Egg Size, and Egg Quality

, 1985
L.J. KLING, R.O. HAWES, R.W. Gerry, William A. Halteman   +3 more
openalex   +1 more source

Adaptaquin is selectively toxic to glioma stem cells through disruption of iron and cholesterol metabolism

Molecular Oncology, EarlyView.
Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié, Davod R. Shah, Eliane E. S. Brechbühl, Michael McNicholas, Zhaoyang Xu, John H. Stockley, Laura Morcom, Diana Gold Diaz, Gemma C. Girdler, Rachel V. Seear, Gabriel Balmus, Rajiv R. Ratan, Harry Bulstrode, James A. Nathan, Manav Pathania, Kevin M. Brindle, David H. Rowitch   +16 more
wiley   +1 more source

AI-embodied multi-modal flexible electronic robots with programmable sensing, actuating and self-learning. [PDF]

Nat Commun
Li J, Xu Z, Li N, Zhang K, Xiong G, Sun M, Hou C, Ji J, Zhang F, Zhong J, Huang Y.   +10 more
europepmc   +1 more source

A DEMONSTRATIVE STUDY OF ASEISMIC DESIGN ON A LARGE TURBINE BUILDING WITH K-TYPE BRACED FRAME : Part 2 Design of K-type braced frame and its ultimate strength

, 1986
Kiyoshi Muto, Tsunehisa Tsugawa, YUKIYOSHI GOTO   +2 more
openalex   +2 more sources

Predictors of response and rational combinations for the novel MCL‐1 inhibitor MIK665 in acute myeloid leukemia

Molecular Oncology, EarlyView.
This study characterizes the responses of primary acute myeloid leukemia (AML) patient samples to the MCL‐1 inhibitor MIK665. The results revealed that monocytic differentiation is associated with MIK665 sensitivity. Conversely, elevated ABCB1 expression is a potential biomarker of resistance to the treatment, which can be overcome by the combination ...
Joseph Saad, Rhiannon Newman, Elmira Khabusheva, Sofia Aakko, Eric Durand, Mahesh Tambe, Heikki Kuusanmäki, Alun Parsons, Juho J. Miettinen, Komal Kumar Javarappa, Ezgi June Olgac, Nemo Ikonen, Mika Kontro, Kimmo Porkka, Heiko Maacke, Janghee Woo, Ensar Halilovic, Caroline A. Heckman   +17 more
wiley   +1 more source

Advanced Integral Type Reactors: Passive Safety Design and Experiment

Science and Technology of Nuclear Installations, 2015
Li Shengqiang, Yanping Huang, Luciano Burgazzi, Annalisa Manera   +3 more
doaj   +1 more source

Engineering gene drive docking sites in a haplolethal locus in Anopheles gambiae. [PDF]

Sci Rep
Smidler AL, Marrogi EA, Scott S, Mameli E, Abernathy D, Akbari OS, Church GM, Catteruccia F, Esvelt K.   +8 more
europepmc   +1 more source

Procedure for a Design and Analysis of Hanger-type Connections

, 1985
Abolhassan Astaneh‐Asl
openalex   +2 more sources

Feasibility of a ctDNA multigenic panel for non‐small‐cell lung cancer early detection and disease surveillance

Molecular Oncology, EarlyView.
Plasma‐based detection of actionable mutations is a promising approach in lung cancer management. Analysis of ctDNA with a multigene NGS panel identified TP53, KRAS, and EGFR as the most frequently altered, with TP53 and KRAS in treatment‐naïve patients and TP53 and EGFR in previously treated patients.
Giovanna Maria Stanfoca Casagrande, Marcela de Oliveira Silva, Mariana Bisarro dos Reis, Rodrigo de Oliveira Cavagna, Luciane Sussuchi, Icaro Alves Pinto, Natalia Zampieri Pontes, Rodrigo Sampaio Chiarantano, Flavio Augusto Ferreira da Silva, Pedro de Marchi, Letícia Ferro Leal, Rui M. Reis   +11 more
wiley   +1 more source