Results 51 to 60 of about 3,278,641 (315)

A Cre‐dependent lentiviral vector for neuron subtype‐specific expression of large proteins

open access: yesFEBS Letters, EarlyView.
We designed a versatile and modular lentivector comprising a Cre‐dependent switch and self‐cleaving 2A peptide and tested it for co‐expression of GFP and a 2.8 kb gene of interest (GOI) in mouse cortical parvalbumin (PV+) interneurons and midbrain dopamine (TH+) neurons.
Weixuan Xue   +6 more
wiley   +1 more source

Swedish Typo-Morphology – Morphological Conceptualizations and Implication for Urban Design

open access: yesIconarp International Journal of Architecture and Planning, 2019
Typo-morphology is a branch of urban morphology that understands physical form, formation and transformation in cities with use of types and typologies.
Todor Stojanovski
doaj   +1 more source

By dawn or dusk—how circadian timing rewrites bacterial infection outcomes

open access: yesFEBS Letters, EarlyView.
The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo   +2 more
wiley   +1 more source

Development of the crossbow-type launcher for a small reconnaissance robot based on the axiomatic theorem

open access: yesJournal of Advanced Mechanical Design, Systems, and Manufacturing, 2016
Recently, the development of small reconnaissance robots has been actively studied for the purpose of remote monitoring. However, difficulties related to the robot gaining access to a distant target area have been encountered in this research area.
Chul Young KIM   +3 more
doaj   +1 more source

Design types in diversified city administration

open access: hybrid, 2022
Sampsa Hyysalo   +5 more
openalex   +2 more sources

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

open access: yesFEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes   +3 more
wiley   +1 more source

The imaging assessment and specific endograft design for the endovascular repair of ascending aortic dissection

open access: yesClinical Interventions in Aging, 2016
Yepeng Zhang,1 Hanfei Tang,1 JianPing Zhou,2 Zhao Liu,1 Changjian Liu,1 Tong Qiao,1 Min Zhou1 1Department of Vascular Surgery, The Affiliated Hospital of Nanjing University Medical School, Nanjing, 2Department of General Surgery, Yixin People’s ...
Zhang Y   +6 more
doaj  

Design of a mine-used bus type optical substation

open access: yesMeikuang Anquan
The coal mine safety monitoring system plays a very important role in coal mine safety production. It mainly collects sensor disaster information such as methane and carbon monoxide through monitoring substations and analyzes it in real time to achieve ...
Fei DENG
doaj   +1 more source

Structural insights into lacto‐N‐biose I recognition by a family 32 carbohydrate‐binding module from Bifidobacterium bifidum

open access: yesFEBS Letters, EarlyView.
Bifidobacterium bifidum establishes symbiosis with infants by metabolizing lacto‐N‐biose I (LNB) from human milk oligosaccharides (HMOs). The extracellular multidomain enzyme LnbB drives this process, releasing LNB via its catalytic glycoside hydrolase family 20 (GH20) lacto‐N‐biosidase domain.
Xinzhe Zhang   +5 more
wiley   +1 more source

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