Results 51 to 60 of about 31,306,322 (385)

Fuzzy logic control for energy saving in autonomous electric vehicles [PDF]

open access: yes, 2014
Limited battery capacity and excessive battery dimensions have been two major limiting factors in the rapid advancement of electric vehicles. An alternative to increasing battery capacities is to use better: intelligent control techniques which save ...
Al-Jazaeri, Ahmed O.   +3 more
core   +1 more source

Mechanisms and kinetic assays of aminoacyl‐tRNA synthetases

open access: yesFEBS Letters, EarlyView.
Accurate protein synthesis is crucial for life. The key players are aminoacyl‐tRNA synthetases (AARSs), which read the genetic code by pairing cognate amino acids and tRNAs. AARSs establish high amino acid selectivity by employing physicochemical limits in molecular recognition.
Igor Zivkovic   +2 more
wiley   +1 more source

A DC to 40GHz Low Cost Surface Mountable RF-VIA TM Package [PDF]

open access: yes, 2001
The ultimate goal for low cost packages for millimeterwave MMIC is to realize a miniature, light weight surface mount type package. This paper describes the design technologies of newly developed package, where we optimized via design by multilayer ...
Morioka, Shigeki   +3 more
core   +1 more source

The epithelial barrier theory proposes a comprehensive explanation for the origins of allergic and other chronic noncommunicable diseases

open access: yesFEBS Letters, EarlyView.
Exposure to common noxious agents (1), including allergens, pollutants, and micro‐nanoplastics, can cause epithelial barrier damage (2) in our body's protective linings. This may trigger an immune response to our microbiome (3). The epithelial barrier theory explains how this process can lead to chronic noncommunicable diseases (4) affecting organs ...
Can Zeyneloglu   +17 more
wiley   +1 more source

From omics to AI—mapping the pathogenic pathways in type 2 diabetes

open access: yesFEBS Letters, EarlyView.
Integrating multi‐omics data with AI‐based modelling (unsupervised and supervised machine learning) identify optimal patient clusters, informing AI‐driven accurate risk stratification. Digital twins simulate individual trajectories in real time, guiding precision medicine by matching patients to targeted therapies.
Siobhán O'Sullivan   +2 more
wiley   +1 more source

Representing Isabelle in LF

open access: yes, 2010
LF has been designed and successfully used as a meta-logical framework to represent and reason about object logics. Here we design a representation of the Isabelle logical framework in LF using the recently introduced module system for LF.
Florian Rabe, Karl Crary, Marino Miculan
core   +2 more sources

Thermostable neutral metalloprotease from Geobacillus sp. EA1 does not share thermolysin's preference for substrates with leucine at the P1′ position

open access: yesFEBS Letters, EarlyView.
Knowing how proteases recognise preferred substrates facilitates matching proteases to applications. The S1′ pocket of protease EA1 directs cleavage to the N‐terminal side of hydrophobic residues, particularly leucine. The S1′ pocket of thermolysin differs from EA's at only one position (leucine in place of phenylalanine), which decreases cleavage ...
Grant R. Broomfield   +3 more
wiley   +1 more source

Design Principles of the Rotary Type 9 Secretion System

open access: yesFrontiers in Microbiology, 2022
The Fo ATP synthase, the bacterial flagellar motor, and the bacterial type 9 secretion system (T9SS) are the three known proton motive force driven biological rotary motors.
Abhishek Trivedi   +9 more
doaj   +1 more source

Evolutionary model type selection for global surrogate modeling [PDF]

open access: yes, 2009
Due to the scale and computational complexity of currently used simulation codes, global surrogate (metamodels) models have become indispensable tools for exploring and understanding the design space.
De Turck, Filip   +2 more
core   +1 more source

Exploring lipid diversity and minimalism to define membrane requirements for synthetic cells

open access: yesFEBS Letters, EarlyView.
Designing the lipid membrane of synthetic cells is a complex task, in which its various roles (among them solute transport, membrane protein support, and self‐replication) should all be integrated. In this review, we report the latest top‐down and bottom‐up advances and discuss compatibility and complexity issues of current engineering approaches ...
Sergiy Gan   +2 more
wiley   +1 more source

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