Results 71 to 80 of about 2,088,428 (332)

Top-phobic heavy Higgs boson as the 750 GeV diphoton resonance

open access: yes, 2016
A hint of a new resonance at a mass of 750\,GeV has been observed in the diphoton channel of LHC Run 2 at $\sqrt{s}=13$ TeV. The signal rate is too large to interpret it as a new Higgs boson in the context of weakly-coupled renormalizable models. One way
Kang, Sin Kyu, Song, Jeonghyeon
core   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

Cohomology and Support Varieties for Lie Superalgebras II

open access: yes, 2006
In \cite{BKN} the authors initiated a study of the representation theory of classical Lie superalgebras via a cohomological approach. Detecting subalgebras were constructed and a theory of support varieties was developed.
Boe, Brian D.   +2 more
core   +2 more sources

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

open access: yesFEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson   +7 more
wiley   +1 more source

Understanding Power and Rules of Thumb for Determining Sample Sizes [PDF]

open access: yesTutorials in Quantitative Methods for Psychology, 2007
This article addresses the definition of power and its relationship to Type I and Type II errors. We discuss the relationship of sample size and power.
Betsy L. Morgan   +1 more
doaj  

Assessment of Renal Osteodystrophy via Computational Analysis of Label-free Raman Detection of Multiple Biomarkers

open access: yesDiagnostics, 2020
Accurate clinical evaluation of renal osteodystrophy (ROD) is currently accomplished using invasive in vivo transiliac bone biopsy, followed by in vitro histomorphometry.
Marian Manciu   +7 more
doaj   +1 more source

Judicial Errors and Crime Deterrence: Theory and Experimental Evidence [PDF]

open access: yes
The standard economic theory of crime deterrence predicts that the conviction of an innocent (type-I error) is as detrimental to deterrence as the acquittal of a guilty individual (type-II error).
Luca Stanca, Matteo Rizzolli
core  

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

COMPARISON OF THE GENERAL LOGARITHMIC FORMS’ POWER OF STATISTICAL CRITERIA OF THE HARMONIC MEAN USING THE HYPOTHESIS OF NORMAL DISTRIBUTION OF SMALL SAMPLE DATA

open access: yesИзвестия высших учебных заведений. Поволжский регион:Технические науки, 2020
Background. The purpose of the article is to compare the probabilities of type I errors for the statistical chi-square test and two new statistical tests with the harmonic mean in normal and logarithmic forms. Materials and methods.
V. S. Lukin
doaj   +1 more source

A Response-Adaptive Method for Design of Validation Experiments in Computational Mechanics

open access: yesApplied Sciences, 2020
For model verification and validation (V & V) in computational mechanics, a hypothesis test for the validity check (HTVC) is useful, in particular, with a limited number of experimental data.
Byung C. Jung   +4 more
doaj   +1 more source

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