Results 111 to 120 of about 646,289 (312)

Versican splice variant messenger RNA expression in normal human Achilles tendon and tendinopathies [PDF]

, 2004
Versican is the principal large proteoglycan expressed in mid-tendon, but its role in tendon pathology is unknown. Our objective was to define the expression of versican isoform splice variant messenger ribonucleic acid (mRNA) in normal Achilles tendons,
Corps, AN, Costa, ML, Hazleman, BL, Ireland, DC, Movin, T, Riley, GP, Robinson, AHN   +6 more
core   +2 more sources

Elevated serum levels of anti-collagen type I antibodies in patients with spontaneous cervical artery dissection and ischemic stroke: a prospective multicenter study

Frontiers in Immunology
IntroductionSpontaneous cervical artery dissection (sCAD) is a rare vasculopathy whose trigger is still unknown. We hypothesized that autoimmunity against components of the vascular wall might play a critical role in sCAD and examined anti-collagen type ...
Silke Zimmermann, Markus Weißenfels, Norma Krümmer, Wolfgang Härtig, Gesa Weise, Daniela Branzan, Dominik Michalski, Johann Otto Pelz   +7 more
doaj   +1 more source

Raman Microscopy at the Organic–Inorganic Interfaces in Human Calcified Aortic Valves Shows the Co‐Existence of Whitlockite Crystals and Carbonated Hydroxyapatite‐Mineralized Collagen Fibrils

Advanced Functional Materials, EarlyView.
This study advances our understanding of aortic valve stenosis by capturing spatially resolved chemical and structural changes at the nanoscale. The findings highlight the potential of combined Raman and electron microscopy for understanding calcification mechanisms across diverse tissue types.
Robin H. M. Van der Meijden, Carolien T. A Kuster, Amber van Broekhoven, Raphaela Allgayer, Luco Rutten, Rona Roverts, Marta Cerruti, Elena Macías‐Sánchez, Jan Hein Cornel, Salloua el Messaoudi, Anat Akiva, Nico Sommerdijk   +11 more
wiley   +1 more source

Relationships between Osteopontin, Osteoprotegerin, and Other Extracellular Matrix Proteins in Calcifying Arteries

Biomedicines
Osteopontin (OPN) and osteoprotegerin (OPG) are glycoproteins that participate in the regulation of tissue biomineralization. The aim of the project is to verify the hypothesis that the content of OPN and OPG in the aorta walls increases with the ...
Aleksandra Kuzan, Agnieszka Chwiłkowska, Krzysztof Maksymowicz, Urszula Abramczyk, Andrzej Gamian   +4 more
doaj   +1 more source

Promotion of minTBP-1-PRGDN on the attachment, proliferation and collagen I synthesis of human keratocyte on titanium

International Journal of Ophthalmology, 2014
AIM:To investigate the influence of minTBP-1-PRGDN on the attachment, proliferation and collagen I synthesis of human keratocyte on titanium (Ti) surface.METHODS:The chimeric peptide RKLPDAPRGDN (minTBP-1-PRGDN) was synthesized by connecting RKLPDA ...
Xin-Yu Li, Cai-Ni Ji, Ling-Juan Xu, Wei-Kun Hu, Bin Zhou, Gui-Gang Li   +5 more
doaj   +1 more source

Bio‐Orthogonally Crosslinked Supramolecular Polymer Bottlebrush Hydrogels for Long‐Term 3D Cell Culture

Advanced Functional Materials, EarlyView.
Fibrous benzenetrispeptide (BTP) hydrogels, fabricated via strain‐promoted azide‐alkyne cycloaddition (SPAAC) crosslinking, form robust, bioinert networks. These hydrogels can support 3D cell culture, where cell viability and colony growth depend on the fiber content.
Ceren C. Pihlamagi, David Pretzel, Peer Nölte, Kourosh Rezaei, Ulrich S. Schubert, Johannes C. Brendel   +5 more
wiley   +1 more source

Synthetic collagen fascicles for the regeneration of tendon tissue. [PDF]

, 2012
The structure of an ideal scaffold for tendon regeneration must be designed to provide a mechanical, structural and chemotactic microenvironment for native cellular activity to synthesize functional (i.e. load bearing) tissue.
Best, SM, Brookes, R, Cameron, RE, Enea, D, Gwynne, JH, Kew, SJ, Rushton, N   +6 more
core   +1 more source

High‐Resolution and Real‐Time In Situ Generation of Cellular Spheroids by Laser‐Assisted Bioprinting for Guided Microvascularization

Advanced Functional Materials, EarlyView.
Micro‐injection laser‐assisted bioprinting enables ultrafast and precise patterning of small endothelial cell spheroids by injecting a highly concentrated single‐cell suspension into GelMA/ColMA hydrogels. In co‐culture with fibroblasts, controlled pre‐vasculogenic network formation is obtained at microscale resolution.
Charles Handschin, Katharina Wulz, Clotilde Jugie, Marie‐Laure Stachowicz, Shane Fennell, Aurélien Mazet, Malou Lea, Nathalie Dusserre, Jean‐Christophe Fricain, Hugo Oliveira   +9 more
wiley   +1 more source

CEACAM1 negatively regulates platelet-collagen interactions and thrombus growth in vitro and in vivo [PDF]

, 2009
Carcinoembryonic antigen cell adhesion molecule-1 (CEACAM1) is a surface glycoprotein expressed on various blood cells, epithelial cells, and vascular cells.
Beauchemin, N, Chand, R, Jackson, D, Liu, Y, Ni, H, Nieswandt, B, Oates, L, Reheman, A, Wee, J, Wong, C, Yip, C   +10 more
core  

Type I collagen fibrils: an inducer of invadosomes

Oncotarget, 2015
Cell-extracellular matrix (ECM) interaction controls a multitude of biological and cellular processes such as adhesion, migration, invasion, gene activation, differentiation and proliferation. ECM constitutes a complex and dynamic structure; indeed there are a lot of molecular components able to participate to the ECM formation.
Julie, Di Martino, Violaine, Moreau, Frederic, Saltel   +2 more
openaire   +2 more sources