Results 141 to 150 of about 646,289 (312)
Advanced Healthcare Materials, EarlyView.Coagulative granular hydrogels are composed of packed thrombin‐functionalized microgels that catalyze the conversion of fibrinogen into a secondary fibrin network, filling the interstitial voids. This bio‐inspired approach stabilizes the biomaterial to match the robustness of bulk hydrogels without compromising injectability, mimicking the initial ...
Zhipeng Deng +16 more
wiley +1 more source
Interface Property of Collagen and Hydroxyapatite in Bone [PDF]
, 2015 When looking at bone at the nanoscale, it consists of a matrix of type I collagen and hydroxyapatite (HAP). Type I collagen is the most abundant protein in the body and together with the mineral HAP [Ca10(PO4)6(OH)2] is responsible for most of the ...
Paul, Clint D
core +1 more source
Advanced Healthcare Materials, EarlyView.The repair and regeneration of brain tissue faces both biological and technical challenges. Injectable bioscaffolds offer new opportunities to stimulate tissue regrowth in the brain by recruiting neural stem cells. Here, the translational issues are reviewed that need to be address to advance this promising new therapeutic approach from the bench to ...
Michel Modo, Alena Kisel
wiley +1 more source
The structure and performance of collagen biomaterials : a thesis presented in partial fulfilment of the requirements for the degree of Doctor of Philosophy in Engineering, Massey University, Palmerston North, New Zealand [PDF]
, 2016 Type I collagen materials are used in a wide range of industrial applications. Some examples include leather for shoes and upholstery, acellular dermal matrix (ADM) materials for surgical applications, and bovine pericardium for the fabrication of ...
Wells, Hannah
core
A Novel Decellularized Fibrocartilage Graft Promotes Tympanic Membrane Repair
Advanced Healthcare Materials, EarlyView.An off‐the‐shelf decellularized porcine meniscus fibrocartilage graft (MEND) is engineered for pediatric tympanoplasty. Featuring a microchannel architecture that promotes host cell invasion, MEND rapidly closes tympanic membrane perforations and fully remodels in vivo, outperforming fascia and matching cartilage grafts while avoiding donor‐site ...
Paul M. Gehret +6 more
wiley +1 more source
Promotion of functional heterotrimeric type I collagen via transfection in osteogenesis imperfecta fibroblasts [PDF]
, 2005 only availableOsteogenesis imperfecta (OI) is a heritable disorder due to mutations in type I collagen. Normal type I collagen forms a heterotrimeric protein comprised of two pro1(I) chains and one pro2(I) chain [1(I)22(I)].
Phillips, Charlotte L. +1 more
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Aqueous Two‐Phase Bioinks for Discrete Packing and Compartmentalization of 3D Bioprinted Cells
Advanced Healthcare Materials, EarlyView.Aqueous two‐phase systems (ATPS) enable the formation of biomimetic interfaces crucial for tissue engineering. However, clinical translation remains limited by the challenge of precisely controlling cellular compartmentalization. Here, we developed ATPS biomaterial inks for 3D bioprinting allowing tuneable droplet formation via NaCl modulation.
Martina Marcotulli +17 more
wiley +1 more source
Topography and mechanical properties of single molecules of type I collagen using atomic force microscopy [PDF]
, 2005 Although the mechanical behavior of tendon and bone has been studied for decades, there is still relatively little understanding of the molecular basis for their specific properties.
Bozec, L., Horton, M.
core
Scientific ReportsComprehensive information on the meniscus root microstructure is essential to exactly understand its physiological role and susceptibility to injury. We selected the ovine medial meniscus anterior root (MAR) as model to elucidate the intricate spatial ...
Marta Carretero-Hernández +4 more
doaj +1 more source
Advanced Healthcare Materials, EarlyView.We measure the cell‐specific responses of administering infusible ECM (iECM) in acute myocardial infarction (MI) across multiple timepoints. Using single‐nucleus RNA sequencing and spatial transcriptomics, we measure macrophage activation, fibroblast remodeling, increased vascular development, lymphangiogenesis, cardioprotection, and neurogenesis ...
Joshua M. Mesfin +18 more
wiley +1 more source