Results 231 to 240 of about 105,740 (327)

Biomarkers of Leucine‐Rich Repeat Kinase 2 (LRRK2) and Lysosomal Dysfunction in Progressive Supranuclear Palsy

Movement Disorders, EarlyView.
Abstract Background Common and rare genetic variants in leucine‐rich repeat kinase 2 (LRRK2) have been linked with sporadic and familial Parkinson's disease (PD). Recently, we discovered that common genetic variation near the LRRK2 locus determined survival in progressive supranuclear palsy (PSP).
Louise‐Kristine Nielsen, Joshua L.I. Frost, David P. Vaughan, Raquel Real, Riona Fumi, Marte Theilmann Jensen, Megan Hodgson, Eleanor J. Stafford, Lesley Wu, Olaf Ansorge, Annelies Quaegebeur, Kieren S.J. Allinson, Thomas T. Warner, Zane Jaunmuktane, Anjum Misbahuddin, P. Nigel Leigh, Boyd C.P. Ghosh, Kailash P. Bhatia, Alistair Church, Christopher Kobylecki, Michele T.M. Hu, James B. Rowe, Alan A. Shomo, Danielle L. Graham, Omar S. Mabrouk, Huw R. Morris, Esther M. Sammler, Edwin Jabbari   +27 more
wiley   +1 more source

Untargeted Plasma Proteomic Signatures and Late Graft Failure in Kidney Transplant Recipients. [PDF]

Transplantation
Shehab NBN, Eskandari SK, Szili-Torok T, Faiz A, van der Ploeg EA, Brotons AS, Teitsma GJ, Gan CT, Burgess JK, Cremers T, Azzi JR, de Borst MH, Bunte K, Horvatovich P, Bakker SJL.   +14 more
europepmc   +1 more source

Prognosis in Parkinson's Disease: An Individual Patient Data Meta‐Analysis of Six European Incidence Cohorts

Movement Disorders, EarlyView.
Abstract Background An accurate understanding of prognosis in Parkinson's disease (PD) is important for patient information provision, personalized treatment, and clinical trial design, but most previous research has been biased towards younger, healthier patients.
Angus D. Macleod, David J. McLernon, Marta Camacho, Caroline H. Williams‐Gray, Rachael A. Lawson, Alison J. Yarnall, David Bäckström, Lars Forsgren, Jodi Maple‐Grødem, Guido Alves, Ole‐Bjørn Tysnes, Carl E. Counsell, Parkinson's Incidence Cohorts Collaboration, Thomas Foltynie, Sarah L. Mason, Ruwani Wijeyekoon, Jonathan Evans, David P. Breen, Gemma Cummins, Krista Farrell, Kirsten Scott, Tom Stoker, Julia Greenland, Natalie Valle Guzman, Lucy Collins, Simon Stott, Jan Linder, Mona Edström, Jörgen Andersson, Linda Eriksson, Gun‐Marie Hariz, Magdalena Domellöf, Michaela Dreetz Gjerstad, Kenn Freddy Pedersen, Elin Bjelland Forsaa, Veslemøy Hamre Frantzen, Anita Laugaland, Johannes Lange, Karen Simonsen, Eldbjørg Fiske, Ingvild Dalen, Bernd Müller, Geir Olve Skeie, Marit Renså, Wenche Telstad, Aliaksei Labusau, Jane Kastet, Ineke HogenEsch, Marianne Kjerandsen, Liv Kari Håland, Karen Herlofson, Solgunn Ongre, Siri Bruun, David Burn, Lynn Rochester, Gordon W. Duncan, Tien K. Khoo, Kate S. M. Taylor, Robert Caslake, David J. M. McGhee, Diane Swallow, Joanne Gordon, Clare Harris, Ann Hayman, Nicola Johannesson, Hazel Forbes, Valerie Angus, Alasdair Finlayson, David Dawson, Katie Wilde, David Ritchie, Artur Wozniak, Adrian Martin   +72 more
wiley   +1 more source

Implementation of a new histological grading system in ovarian mucinous carcinomas and its association with the risk of recurrence: a retrospective cohort study. [PDF]

Sao Paulo Med J
Yoshida A, Andrade LALA, Almeida RRG, Machado HDC, Sarian LO, Derchain S.   +5 more
europepmc   +1 more source

Healthy Dietary Patterns and Risk of Parkinson's Disease

Movement Disorders, EarlyView.
Abstract Background Although healthy dietary patterns have been suggested to be associated with decreased Parkinson's disease (PD) risk, their protective role remains uncertain. Objective To examine associations between eight dietary patterns and PD risk in two United States (US) cohorts followed for up to 32 years.
Xiao Chen, Hui Chen, Peilu Wang, Michael A. Schwarzschild, Albert Y. Hung, Xiang Gao, Alberto Ascherio, Mario H. Flores‐Torres, Kjetil Bjornevik   +8 more
wiley   +1 more source

Association of Age with Outcomes in Adrenocortical Carcinoma: A Combined Cancer Registry and Multi-Omic Analysis. [PDF]

Cancers (Basel)
Remer LF, Shanker RM, Meyer TJ, Lew JI, Nilubol N.   +4 more
europepmc   +1 more source

On Order Restricted Inference in Multi‐Step Stage Life Testing for a General Family of Distributions

Naval Research Logistics (NRL), EarlyView.
ABSTRACT Recently, k$$ k $$‐step stage life testing (SLT) has been proposed by Laumen and Cramer (2021) as a natural extension of progressive censoring with fixed censoring times (PC‐FCT) as well as of simple step‐stress accelerated life testing (SSALT).
Erhard Cramer, Ayan Pal, Debashis Samanta   +2 more
wiley   +1 more source

Immunohistochemical analysis of Enolase-1 sublocalization in benign and malignant breast tumors: potential implications for tumor progression and prognosis. [PDF]

Front Oncol
Baracioli LS, Rezende CP, Dos Santos E Silva L, Alves DL, da Nóbrega DF, Chuffa LGA, Zuccari DAPC.   +6 more
europepmc   +1 more source

Association of Glucagon‐Like Peptide‐1 Receptor Agonists With Cancer Risk in Older Adults With Type 2 Diabetes

Obesity, EarlyView.
ABSTRACT Objective The real‐world evidence on the association between glucagon‐like peptide‐1 receptor agonists (GLP‐1RAs) and cancer risk remains limited and mixed. Methods In 2013–2020 national Medicare claims data, we included cancer‐naïve patients with type 2 diabetes (T2D). We identified those who initiated GLP‐1 RA, sodium‐glucose cotransporter 2
Ying Lu, Hao Dai, Huilin Tang, William T. Donahoo, Thomas J. George, Ramon C. Sun, Sizun Jiang, Aik Choon Tan, Yi Guo, Jonathan D. Licht, John M. Allen, Kelvin P. Lee, Jingchuan Guo, Jiang Bian   +13 more
wiley   +1 more source

Dogs' reactions to motivations and emotions in conspecific and heterospecific vocalizations. [PDF]

Sci Rep
Faragó T, Kocsis L, Laczi B, Atares IR, Fraga PP, Audiguier M, Rhali SB, Slocombe KE, Kubinyi E, Andics A.   +9 more
europepmc   +1 more source