Results 11 to 20 of about 13,800,549 (299)
Adiposity-Related Heterogeneity in Patterns of Type 2 Diabetes Susceptibility Observed in Genome-Wide Association Data [PDF]
, 2009 OBJECTIVE-This study examined how differences in the BMI distribution of type 2 diabetic case subjects affected genome-wide patterns of type 2 diabetes, association mid considered the implications for the etiological heterogeneity of type 2 diabetes ...Timpson, NJ, David P. Strachan, Weedon, Michael N., Weedon, MN, Nicholas J. Timpson, Rayner, NW, Morris, Andrew D., Zeggini, Eleftheria, Mark Walker, Alex S.F. Doney, Doney, ASF, Palmer, Colin N A, Timothy M. Frayling, Strachan, David P., Hitman, Graham A., Lindgren, Cecilia M., Hattersley, Andrew T., Hitman, GA, Lindgren, CM, Randall, Joshua, Doney, Alex S. F.; id_orcid, Graham A. Hitman, Andrew T. Hattersley, Walker, Mark, Palmer, CN, Hattersley, AT, Rayner, N. William, McCarthy, MI, Timpson, Nicholas J., Michael N. Weedon, Willem H. Ouwehand, Palmer, CNA, Walker, M, Andrew D. Morris, Doney, Alex S F, N. William Rayner, Randall, J, Mark I. McCarthy, Frayling, Timothy M., Strachan, DP, Morris, AD, Cecilia M. Lindgren, Doney, AS, Joshua Randall, McCarthy, Mark I., Zeggini, E, Eleftheria Zeggini, Ouwehand, WH, Pamler, CAN, Ouwehand, Willem H., Colin N.A. Palmer, Frayling, TM, Palmer, Colin N. A.; id_orcid +52 morecore +1 more sourceRoles of Bcl-3 in the pathogenesis of murine type 1 diabetes [PDF]
, 2010 OBJECTIVE: It has long been recognized that autoimmunity is often associated with immunodeficiency. The mechanism underlying this paradox is not well understood.Ruaidhri J. Carmody, Shi-Jun Zheng, Scott Palmer, Palmer, S., Ruan, Q., Chen, Y.H., Carmody, R.J., Youhai H. Chen, Zheng, S.-J., Qingguo Ruan +9 morecore +1 more sourceProgression to microalbuminuria in type 1 diabetes: development and validation of a prediction rule [PDF]
, 2009 AIMS/HYPOTHESIS: Microalbuminuria is common in type 1 diabetes and is associated with an increased risk of renal and cardiovascular disease. We aimed to develop and validate a clinical prediction rule that estimates the absolute risk of microalbuminuria. K. G. M. Moons, P.-H. Groop, S. S. Soedamah-Muthu, M. Rewers, Y. Vergouwe, J. H. Fuller, C. Forsblom, Orchard, T.J., Rewers, M., Forsblom, C., Snell-Bergeon, J.K., T. J. Orchard, Fuller, J.H., D. M. Maahs, J. K. Snell-Bergeon, J. Zgibor, Vergouwe, Y., Moons, K.G.M., N. Chaturvedi, Groop, P.H., Soedamah-Muthu, S.S., Zgibor, J., Maahs, D.M., Chaturvedi, N. +23 morecore +1 more sourceBreast-Feeding and Childhood-Onset Type 1 Diabetes : A pooled analysis of individual participant data from 43 observational studies [PDF]
, 2012 OBJECTIVE To investigate if there is a reduced risk of type 1 diabetes in children breastfed or exclusively breastfed by performing a pooled analysis with adjustment for recognized confounders. RESEARCH DESIGN AND METHODS Relevant studies were identified Cinek, O., Joner, Geir, Brigis, G, Parslow, Roger C, Joner, Geir,, Geir Joner (8519850), Schober, E, Stene, Lars C, Radon, K, Carine E de Beaufort (16166561), Devoti, Gabriele, Karavanaki, K, Rosenbauer, Joachim,, Cardwell, Chris R, Ponsonby, Anne-Louise, Stene, Lars C., Stene, Lars C,, Memon, Anjum, Joner, G, Savilahti, E., Ionescu-Tirgoviste, C., C Patterson, Chris,, Urbonaite, B., Devoti, G., Patterson, Chris C., Constantin Ionescu-Tirgoviste (542793), Memon, A., Urbonaite, Brone,, Patterson, Christopher, Strotmeyer, ES, Urbonaite, Brone, Chetwynd, Amanda,, Cardwell, Christopher; id_orcid, Lee-Ming Chuang (215892), Svensson, Jannet, Pozzilli, Paolo, Perez-Bravo, Francisco,, Wadsworth, Emma J.K., Chuang, Lee-Ming,, Brone Urbonaite (16166552), Benson, Victoria,, Gimeno, S.G., de Beaufort, Carine E, Pozzilli, P., DE BEAUFORT, Carine, Stene, LC, C Patterson, Chris, Radon, Katja, Karavanaki, Kyriaki,, Svensson, J., Goldacre, MJ, Michael J Goldacre (8832635), Katja Radon (487886), Goldacre, Michael J,, 莊立民, Goldacre, Michael J., Benson, V, Gimeno, Suely Godoy Agostinho [UNIFESP], Ludvigsson, Johnny, Joner, G., Paolo Pozzilli (310706), Savilahti, Erkki, Sipetic, Sandra,, Schober, E., Sipetic, Sandra, Rabiei, S, Brigis, Girts,, Anjum Memon (4461844), de Beaufort, Carine E,, Svensson, J, Cinek, Ondrej, Mona Salem (16166564), Chuang, Lee-Ming, Benson, V., Sandra Sipetic (16166558), Salem, Mona, Elsa S Strotmeyer (16166546), Perez-Bravo, Francisco, Patterson, CC, Strotmeyer, E.S., Karavanaki, K., Salem, Mona,, Brigis, G., Wadsworth, Emma J K,, Cardwell, CR, Perez-Bravo, F, Victoria Benson (6821780), Karavanaki, Kyriaki, Girts Brigis (4725450), Chetwynd, Amanda, Schober, Edith,, Roger C Parslow (9861266), Goldacre, M.J., Kyriaki Karavanaki (336472), Rabiei, Samira,, Ionescu-Tirgoviste, Constantin,, Rabiei, Samira, De Beaufort, Carine E., Sipetic, S, Cinek, O, Chuang, LM, Patterson, Chris C, Rosenbauer, Joachim, Schober, Edith, Chetwynd, A., Memon, A, Gimeno, SG, Ondrej Cinek (196591), Harrild, K., Ponsonby, Anne-Louise,, Svensson, Jannet,, Anne-Louise Ponsonby (340858), Chuang, Lee Ming, Beaufort, Carine E. de, Chris R Cardwell (5356490), Jannet Svensson (418468), Chetwynd, A, Ionescu-Tirgoviste, Constantin, Savilahti, Erkki,, Lars C Stene (16166537), Suely G Gimeno (16166540), Memon, Anjum,, Ponsonby, AL, Strotmeyer, Elsa S, Brigis, Girts, Rosenbauer, J., Chris C Patterson (5364881), Radon, Katja,, Parslow, RC, Wadsworth, EJK, Emma J K Wadsworth (16166543), Harrild, K, Parslow, R.C., Cardwell, Chris R., De Beaufort, CE, Ionescu-Tirgoviste, C, Cardwell, Chris R,, Devoti, G, Cardwell, C.R., Salem, M., Samira Rabiei (16166567), Cardwell, Chris R.;Stene, Lars C.;Ludvigsson, Johnny;Rosenbauer, Joachim;Cinek, Ondrej;Svensson, Jannet;Perez-Bravo, Francisco;Memon, Anjum;Gimeno, Suely G.;Wadsworth, Emma J. K.;Strotmeyer, Elsa S.;Goldacre, Michael J.;Radon, Katja;Chuang, Lee-Ming;Parslow, Roger C.;Chetwynd, Amanda;Karavanaki, Kyriaki;Brigis, Girts;Pozzilli, Paolo;Urbonaite, Brone;Schober, Edith;Devoti, Gabriele;Sipetic, Sandra;Joner, Geir;Ionescu-Tirgoviste, Constantin;de Beaufort, Carine E.;Harrild, Kirsten;Benson, Victoria;Savilahti, Erkki;Ponsonby, Anne-Louise;Salem, Mona;Rabiei, Samira;Patterson, Chris C., Edith Schober (640994), Wadsworth, Emma J. K., Cinek, Ondrej,, Ponsonby, A.L., Ponsonby, Anne Louise, Ludvigsson, J, Savilahti, E, Francisco Perez-Bravo (206402), Parslow, Roger C., Johnny Ludvigsson (167260), Benson, Victoria, Amanda Chetwynd (16166549), Wadsworth, Emma J K, Parslow, Roger C,, Ludvigsson, J., Sipetic, S., Rabiei, S., Stene, L.C., Rosenbauer, J, Pozzilli, P, Chuang, L.M., Erkki Savilahti (68955), Strotmeyer, Elsa S., Urbonaite, B, Wadsworth, E.J., Strotmeyer, Elsa S,, Devoti, Gabriele,, Ludvigsson, Johnny,, Joachim Rosenbauer (445335), Gimeno, Suely G, Perez-Bravo, F., Radon, K., Patterson, C.C., Pozzilli, Paolo,, Harrild, Kirsten, Gimeno, Suely G,, Salem, M, Goldacre, Michael J, Gimeno, Suely G., Harrild, Kirsten,, Kirsten Harrild (563534), Gabriele Devoti (16166555) +183 morecore +1 more sourceFetuin-A and type II diabetes mellitus
The Egyptian Journal of Internal Medicine, 2014 Background
The pathophysiology of type II DM is complex; in addition to impaired insulin secretion from Beta-cells, reduced insulin sensitivity was found to play a predominant role in the pathogenesis of the disease.Lamyaa Ismail Ahmed, Sabila Gomaa Mousa, Nagwa Abd El-Ghaffar Mohamed, Zeinab Ahmed Yousry, Mayada Rabea Abd-El Khalaa +4 moredoaj +1 more sourceIs the Recent Rise in Type 2 Diabetes Incidence From 1984 to 2007 Explained by the Trend in Increasing BMI? Evidence from a prospective study of British men [PDF]
, 2010 OBJECTIVE: To estimate the extent to which increasing BMI may explain the rise in type 2 diabetes incidence in British men from 1984 to 2007.RESEARCH DESIGN AND METHODS: A representative cohort ratio of 6,460 British men was followed-up for type 2 ...Morris, RW, Thomas, Mary C, Thomas, MC, Hardoon, Sarah L, Lennon, Lucy T, Whincup, Peter H, Whincup, PH, Hardoon, SL, Morris, Richard W, Wannamethee, S Goya, Lennon, LT, Wannamethee, SG +11 morecore +1 more sourceInsulin gene polymorphisms in type I diabetes, Addison's disease and the polyglandular autoimmune syndrome type II [PDF]
, 2008 Background: Polymorphisms within the insulin gene can influence insulin expression in the pancreas and especially in the thymus, where self-antigens are processed, shaping the T cell repertoire into selftolerance, a process that protects from ß-cell ...Lange, Britta Kristina, Kahles, Heinrich, Reisch, Nicole, Willenberg, Holger S., Seissler, Jürgen, Penna Martinez, Marissa, Badenhoop, Klaus, Ramos-Lopez, Elizabeth, Meyer, Gesine, Hahner, Stefanie, Seissler Jürgen, Lange Britta, Jürgen Seissler, Badenhoop Klaus, Stefanie Hahner, Kahles Heinrich, Marissa Penna-Martinez, Heinrich Kahles, Holger S Willenberg, Reisch Nicole, Penna-Martinez Marissa, Willenberg Holger S, Klaus Badenhoop, Meyer Gesine, Elizabeth Ramos-Lopez, Ramos-Lopez Elizabeth, Gesine Meyer, Hahner Stefanie, Britta Lange, Nicole Reisch +29 morecore +2 more sources