Results 11 to 20 of about 13,800,549 (299)

Role of cytokines in the pathogenesis of type 1 diabetes [PDF]

open access: yes, 1996
This thesis was submitted for the degree of Doctor of Philosophy and awarded by Brunel University.T lymphocytes and macrophages appear to play an important role in mediating ß-cell damage and causing Type 1 diabetes.
Hussain, Munther Jaffar
core   +6 more sources

Systematic review of transition models for young people with long-term conditions: A report for NHS Diabetes. [PDF]

open access: yes, 2013
Aims For many young people with Type 1 diabetes, transition from paediatric to adult care can result in a marked deterioration in glycaemic control.
Day, R, Kime, NH, Bagnall, A
core   +8 more sources

Adiposity-Related Heterogeneity in Patterns of Type 2 Diabetes Susceptibility Observed in Genome-Wide Association Data [PDF]

open access: yes, 2009
OBJECTIVE-This study examined how differences in the BMI distribution of type 2 diabetic case subjects affected genome-wide patterns of type 2 diabetes, association mid considered the implications for the etiological heterogeneity of type 2 diabetes ...
Timpson, NJ   +52 more
core   +1 more source

Roles of Bcl-3 in the pathogenesis of murine type 1 diabetes [PDF]

open access: yes, 2010
OBJECTIVE: It has long been recognized that autoimmunity is often associated with immunodeficiency. The mechanism underlying this paradox is not well understood.
Ruaidhri J. Carmody   +9 more
core   +1 more source

Progression to microalbuminuria in type 1 diabetes: development and validation of a prediction rule [PDF]

open access: yes, 2009
AIMS/HYPOTHESIS: Microalbuminuria is common in type 1 diabetes and is associated with an increased risk of renal and cardiovascular disease. We aimed to develop and validate a clinical prediction rule that estimates the absolute risk of microalbuminuria.
K. G. M. Moons   +23 more
core   +1 more source

Breast-Feeding and Childhood-Onset Type 1 Diabetes : A pooled analysis of individual participant data from 43 observational studies [PDF]

open access: yes, 2012
OBJECTIVE To investigate if there is a reduced risk of type 1 diabetes in children breastfed or exclusively breastfed by performing a pooled analysis with adjustment for recognized confounders. RESEARCH DESIGN AND METHODS Relevant studies were identified
Cinek, O.   +183 more
core   +1 more source

Fetuin-A and type II diabetes mellitus

open access: yesThe Egyptian Journal of Internal Medicine, 2014
Background The pathophysiology of type II DM is complex; in addition to impaired insulin secretion from Beta-cells, reduced insulin sensitivity was found to play a predominant role in the pathogenesis of the disease.
Lamyaa Ismail Ahmed   +4 more
doaj   +1 more source

Status of Serum Magnesium level in Diabetic Retinopathy & Non Retinopathy in the Patients of Type-II Diabetes Mellitus [PDF]

open access: yesJLUMHS, 2018
OBJECTIVE: To compare the serum magnesium levels in normal population, non-complicated patients of type – II diabetes mellitus and complicated patients of type- II diabetes mellitus with retinopathy & to observe the role of serum magnesium in development
Ali Raza Memon   +4 more
doaj   +1 more source

Is the Recent Rise in Type 2 Diabetes Incidence From 1984 to 2007 Explained by the Trend in Increasing BMI? Evidence from a prospective study of British men [PDF]

open access: yes, 2010
OBJECTIVE: To estimate the extent to which increasing BMI may explain the rise in type 2 diabetes incidence in British men from 1984 to 2007.RESEARCH DESIGN AND METHODS: A representative cohort ratio of 6,460 British men was followed-up for type 2 ...
Morris, RW   +11 more
core   +1 more source

Insulin gene polymorphisms in type I diabetes, Addison's disease and the polyglandular autoimmune syndrome type II [PDF]

open access: yes, 2008
Background: Polymorphisms within the insulin gene can influence insulin expression in the pancreas and especially in the thymus, where self-antigens are processed, shaping the T cell repertoire into selftolerance, a process that protects from ß-cell ...
Lange, Britta Kristina   +29 more
core   +2 more sources

Home - About - Disclaimer - Privacy