Diabetes Mellitus : Insulin use [PDF]
, 2003 Insulin is required for normal carbohydrate, protein and fat metabolism. Patients with Type I diabetes depend on exogenous insulin for their survival while Type II diabetics may require insulin at a later stage of their disease.peer ...
Tonna, Antonella
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Preconception counselling in women with diabetes: a population-based study in the North of England [PDF]
, 2009 To investigate the association of preconception counseling with markers of care and maternal characteristics in women with pregestational diabetes. The study includes data from a regional multi-center survey on 588 women with pregestational diabetes who ...
Chandler, Colin +6 more
core +1 more source
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Physical activity in type II diabetes
Journal of Education, Health and SportINTRODUCTION AND AIM OF WORK A factor significantly influencing the risk of lifestyle diseases, including diabetes, is physical activity. The last decades have been characterized by reduced physical activity in developed countries.
Martyna Kępczyk +9 more
doaj +1 more source
Respiratory function in type II diabetes mellitus
Egyptian Journal of Chest Disease and Tuberculosis, 2015 Background: Type 2 diabetes mellitus (DM) and metabolic syndrome (MetS) are particularly common medical disorders and are leading causes of morbidity and mortality worldwide. Pulmonary function can be affected by DM.
Mokhles Abdel Fadil Zineldin +2 more
doaj +1 more source
Prospective study of coffee and tea consumption in relation to risk of type 2 diabetes mellitus among men and women: The Whitehall II study [PDF]
, 2008 At least fourteen cohort studies have documented all inverse association between coffee consumption and risk of type 2 diabetes. We examined the prospective association between coffee and tea consumption and the risk of type 2 diabetes mellitus among ...
Witte, DR +4 more
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Skin microvascular vasodilatory capacity in offspring of two parents with Type 2 diabetes [PDF]
, 2001 Aims<br/> Microvascular dysfunction occurs in Type 2 diabetes and in subjects with fasting hyperglycaemia. It is unclear whether this dysfunction relates to dysglycaemia.
Shore, A.C. +15 more
core +1 more source
Investigating transcription factor dynamics in health and disease using FRAP
FEBS Letters, EarlyView.FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
A Survival Analysis with Cox Regression Interaction Model of Type II Diabetes Mellitus in Indonesian
Jurnal Profesi Medika, 2021 Type II diabetes mellitus is a metabolic syndrome characterized by hyperglycemia. Diabetes is still one of the world's health threats where the number of people with disabilities and mortality rates continue to increase over time.
Simeftiany Indrilemta Lomo +2 more
doaj +1 more source
A model to estimate the lifetime health outcomes of patients with Type 2 diabetes: the United Kingdom Prospective Diabetes Study (UKPDS) Outcomes Model (UKPDS no. 68) [PDF]
, 2004 <i>Aims/hypothesis</i> The aim of this study was to develop a simulation model for Type 2 diabetes that can be used to estimate the likely occurrence of major diabetes-related complications over a lifetime, in order to calculate health ...
Stevenson, R.J. +20 more
core +1 more source