Results 61 to 70 of about 13,800,549 (299)

Artificial Intelligence in Type II Diabetes Mellitus: Screening, Treatment, and Complication

KEMAS: Jurnal Kesehatan Masyarakat
Type II diabetes mellitus is one of the chronic metabolic diseases that are associated with insulin resistance. Type II diabetes mellitus incidence continues to increase each year and may cause various health complications, even death.
Airine Stefanie Lians, Andi Miyanza Rezkyawan Lakipadada Tunru, Chindia Chindia, Juan Alexandra Prasetyo, Justin Kie, Raffael Christian, Sherlyn Sean, Victoria Larasati, Liauw Djai Yen   +8 more
doaj   +1 more source

Neutralization of the PTX3/CD44 axis suppresses TGF‐β1 signaling in kidney fibrosis

FEBS Letters, EarlyView.
This study investigates how the PTX3/CD44 axis promotes kidney fibrosis by activating TGF‐β1 signaling. We demonstrate that the neutralizing antibody WHC‐001 effectively inhibits this pathway, suppressing myofibroblast activation and partial epithelial–mesenchymal transition (EMT).
Chao‐Chun Cheng, Shen‐Shin Chang, Feng‐Wei Chen, Ying‐Chieh Su, Thanh Phuong Nguyen, Yu‐Wei Hsiao, Jhih‐Ying Chi, Hsin‐Yin Liang, Ju‐Ming Wang   +8 more
wiley   +1 more source

Gut microbiota alterations in patients with non‐small‐cell lung cancer undergoing chemoradiotherapy

Molecular Oncology, EarlyView.
We investigated the impact of concurrent chemoradiotherapy (CRT) on the gut microbiota in patients with locally advanced non‐small‐cell lung cancer. Overall gut microbiota composition remained largely stable throughout CRT while antibiotic exposure may influence microbial diversity.
Hanne Marte Nymoen, Zhi Zhao, Henrik Horndalsveen, Maria Moksnes Bjaanæs, Bjørn Henning Grønberg, Tarje Halvorsen, Tesfaye Madebo, Marianne Aanerud, Jussi Koivunen, Kersti Oselin, Saulius Cicenas, Nina Helbekkmo, Jarkko Ahvonen, Maria Silvoniemi, Tine Norman Alver, Tonje Dalen, Åsa Kristina Öjlert, Saima Jamil Farooqi, Åslaug Helland, Vilde Drageset Haakensen   +19 more
wiley   +1 more source

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

FEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj, Eline M. F. de Lange, Klaas A. Sjollema, Ben N. G. Giepmans   +3 more
wiley   +1 more source

Type II Diabetes Mellitus in Arabic-Speaking Countries

International Journal of Endocrinology, 2012
The global epidemic of diabetes has not spared the Arabic-speaking countries, which have some of the highest prevalence of type II diabetes. This is particularly true of the Arab Gulf, a conglomerate of high income, oil-producing countries where ...
Mohammad Badran, Ismail Laher
doaj   +1 more source

Adding pioglitazone to insulin containing regimens in type 2 diabetes : systematic review and meta-analysis [PDF]

, 2009
Background Type 2 diabetes is treated in a stepwise manner, progressing from diet and physical activity to oral antidiabetic agents and insulin. The oral agent pioglitazone is licensed for use with insulin when metformin is contraindicated or not ...
Waugh Norman, Christine Clar, Clar Christine, Waugh, Norman, Norman Waugh, Royle Pamela, Clar, C., Royle, Pamela, Pamela Royle   +8 more
core   +1 more source

Genes and type 2 diabetes: polymorphisms of the EIF2AK3 gene and its relationship to type 2 diabetes mellitus [PDF]

, 2010
MDAims/ Hypothesis: Wolcott- Rallison syndrome (WRS) is a rare autosomal recessively inherited Mendelian disorder. It is characterised by a short trunk compared to arm span, multiple epiphyseal dysplasia, multiple fractures, hepatosplenomegaly and renal ...
Sudagani, Jaidev
core   +4 more sources

Evaluating the effect of γ‐oryzanol on MASLD pathology using a medaka fish model

FEBS Open Bio, EarlyView.
This study explores a liver disease called MASLD, which is increasing worldwide and can lead to serious damage. Researchers used medaka fish instead of rodents to test a food compound, γ‐oryzanol. Fish fed this compound had less liver fat and healthier gut bacteria.
Yukako Ito, Haduki Asano, Ayano Ueki, Joe Sakamoto, Yasuhiro Kamei, Hayato Tokumoto, Ayaka Yazawa, Shigeki Kamitani   +7 more
wiley   +1 more source

Nephropathy of type II diabetes mellitus [PDF]

Nephrology Dialysis Transplantation, 1996
In recent years there has been a dramatic increase of almost epidemic proportions in the incidence of patients with type II diabetes mellitus who reach end-stage renal failure and enter renal replacement programmes. This is mainly due to the greater prevalence and better survival of patients with type II diabetes and diabetic nephropathy.
E, Ritz, C, Keller, K H, Bergis
openaire   +2 more sources

HLA Class I and Genetic Susceptibility to Type 1 Diabetes Results From the Type 1 Diabetes Genetics Consortium

, 2010
OBJECTIVE-We report here genotyping data and type 1 diabetes association analyses for HLA class I loci (A, B, and C) on 1,753 multiplex pedigrees from the Type 1 Diabetes Genetics Consortium (T1DGC), a large international collaborative study.
Joyce A. Carlson, Henry A. Erlich, Priscilla Moonsamy, Lavant, Eva, Noble, Janelle A., Valdes, Ana Maria, Anna Lisa Fear, Louey, Anthony, Anthony Louey, Patrick Concannon, Janelle A. Noble, Concannon, Patrick, Eva Lavant, Lane, Julie A., Rappner, Rebecca, Ana Maria Valdes, Rebecca Rappner, Erlich, Henry A., Moonsamy, Priscilla, Michael D. Varney, Varney, Michael D., Carlson, Joyce, null null, Julie A. Lane, Carlson, Joyce,, Mychaleckyj, Josyf C., Josyf C. Mychaleckyj, Lund University., Fear, Anna Lisa   +28 more
core   +1 more source