Results 121 to 130 of about 10,677,334 (330)

Characterization of collagen profile in peritoneal metastases of colorectal cancer

Scientific Reports
The tumor microenvironment (TME) plays a critical role in cancer progression and response to treatment. In colorectal cancer (CRC), a collagen-rich extracellular matrix (ECM) is a well-established feature of primary tumors and liver metastases.
P. Villarejo-Campos, S. García Gómez-Heras, S. González-Moreno, S. Qian Zhang, R. Franco-Rodríguez, I. Díaz-Caro, R. Olivera-Salazar, D. García-Olmo, M. García-Arranz   +8 more
doaj   +1 more source

Comparative Analysis of the Extracellular Matrix Composition in Proliferating and Involuted Infantile Hemangiomas

Archives of Plastic Surgery, 2015
Background Changes in the composition of the extracellular matrix (ECM) occur between the proliferating and involuted phases of infantile hemangiomas (IH), and are associated with angiogenic growth.
Hyochun Park, Hannara Park, Ho Yun Chung, M O Teresa, Milton Waner   +4 more
doaj   +1 more source

Bone‐Inspired Recyclable Composites for Damage‐Tolerant Circular Materials

Advanced Functional Materials, EarlyView.
Bone‐inspired architected composites are developed by combining osteon‐like reinforcements with a recyclable Elium thermoplastic matrix. The hierarchical architecture redirects cracks and promotes energy dissipation, while enabling recovery of intact, aligned, load‐bearing reinforcement units that retain their original stiffness, revealing a route ...
Alessandro Stagni, Nastaran Bahrami Novin, Luigi Benvenuto, Enrico Lertora, Flavia Libonati   +4 more
wiley   +1 more source

The influence of peptidyl-prolyl cis-trans isomerase on the in vitro folding of type III collagen.

Journal of Biological Chemistry, 1987
Peptidyl-prolyl cis-trans isomerase was extracted from pig kidney cortex and partially purified. Enzyme activity was monitored against the cis-trans isomerization of succinyl-Ala-Ala-Pro-Phe-methylcoumaryl amide by means of a two-step process using ...
H. Bächinger
semanticscholar   +1 more source

Hierarchical Collagen Nanofiber Gels Recapitulate a Physiologically Relevant Tumor Stromal Microenvironment

Advanced Healthcare Materials, EarlyView.
The collagen nanofiber (CNF) gel supports cancer cell culture, exhibiting cell morphology and cancer‐related protein expression similar to Matrigel. It offers a higher collagen concentration than commercial gels. Additionally, the CNF gel allows replication of the high elasticity of in vivo cancer tissue by controlling collagen fiber sizes, ranging ...
Naoko Sasaki, Tomoyuki Suezawa, Shiro Kitano, Ryohei Katayama, Michiya Matsusaki   +4 more
wiley   +1 more source

Hydrogels Augmented With Artificial Sweeteners can Inhibit Multidrug‐Resistant Acinetobacter baumannii Growth and Biofilm Formation While Demonstrating Safety in Pre‐Clinical Pilot Human Trials

Advanced Healthcare Materials, EarlyView.
Using PVA–borax hydrogels as carriers for off‐the‐shelf artificial sweeteners to fight multidrug‐resistant A. baumannii. These soft, biocompatible hydrogels rapidly reduce bacterial viability within multidrug‐resistant A. baumannii biofilms by more than 99% within one hour and sustain antimicrobial activity over time, while demonstrating safety in both
Jie Han, Mohamed Soliman, Bin Zhang, Dominika Krawiel, Ronan R. McCarthy   +4 more
wiley   +1 more source

Collagen Type III.

, 2014
Confocal micrographs demonstrating immunolocalization of type III collagen at 4 weeks in (A, B) HCF, (C, D) CSSC in serum-containing media, and (E, F) CSSC in serum-free media.
Audrey E. K. Hutcheon (511272), James D. Zieske (511273), Yiqin Du (380732), Martha L. Funderburgh (42051), Jian Wu (41301), James L. Funderburgh (42053), Dimitrios Karamichos (511271)   +6 more
core   +1 more source

A Systematic Study of GelMA‐Carbopol Bioinks for High‐Fidelity Extrusion 3D Bioprinting at Physiological Temperatures

Advanced Healthcare Materials, EarlyView.
Gonzalez Martinez and collaborators develop a strategy to formulate high performance GelMA‐based bioinks with low solids contents. The resulting bioinks enable 3D bioprinting at 37 °C of high‐fidelity structures with tunable mechanical properties that support high cell viability and function.
David A. González‐Martínez, Aidee V. Arizpe Tafoya, Eduardo González‐Martínez, Mabel Barreiro Carpio, Laura Daniela Serrano Andrade, Christopher T. N. Chow, Mohammadhossein Dabaghi, Jeremy A. Hirota, Jose M. Moran‐Mirabal   +8 more
wiley   +1 more source

Collagen type I and collagen type III content in myocardium of normal and obese mice.

, 2013
(A and C) Representative immunoblots at eight and 16 months. Tubulin was detected as a loading control. (B and D) Densitometric measurements (arbitrary units).
Marcelo Ezquer (356931), Luis Sobrevia (295521), Felipe Solis (401709), Manuel Lecanda (401708), Jaime Gutiérrez (401710), Paulette Conget (356932), Andrea Leiva (295520), Sebastián D. Calligaris (401707), Enrique Brandan (401711)   +8 more
core   +1 more source

Recombinant type I & III chimeric collagen significantly enhances the vitality of fibroblasts and decelerates the skin aging process

BMC Biotechnology
Collagen, the most abundant protein in the mammalian extracellular matrix, is critical for skin structure and function, with Type I and Type III collagens being particularly important. Collagen degradation in skin is accelerated by aging and UV exposure,
Wei Chen, Ning Wang, Xinshan Xie, Han Liu, Yiting Wang, Yanfeng Nie, Chun Chen, Huaiqing Sun, An Hong, Chaowan Guo, Sheng Xiong   +10 more
doaj   +1 more source