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STRUCTURE-FUNCTION AND BIOGENESIS OF THE TYPE IV PILI

Annual Review of Microbiology, 1993
Type IV pili are adhesins expressed by a number of diverse gram-negative microorganisms. These pili are related through similarities in the primary amino acid sequences of the structural subunits, a conserved assembly machinery, and a similar mechanism of transcriptional regulation.
Mark S Strom, S Lory
exaly   +4 more sources

Type IV pili and cell motility

Molecular Microbiology, 1999
Type IV pili (Tfp) mediate the movement of bacteria over surfaces without the use of flagella. These movements are known as social gliding in Myxococcus xanthus and twitching in organisms such as Pseudomonas aeruginosa and Neisseria gonorrhoeae. Tfp are localized polarly. Type IV pilins have a signature N‐terminal domain, which forms a coiled‐coil with
D, Wall, D, Kaiser
openaire   +2 more sources

Purification of Type IV Pili and Pilin Subunits

2019
The Type IV pili are displayed peritrichously on the surfaces of Neisseria gonorrhoeae cells. Here we present protocols for isolating and purifying Type IV pili and dissociating them into PilE pilin subunits. Pilus filaments are isolated from the bacterial cell surface by mechanical shearing and purified by differential precipitation and centrifugation.
Lisa, Craig, Tuba, Altindal
openaire   +2 more sources

Type II Secretion and Type IV Pili of Francisella

Annals of the New York Academy of Sciences, 2007
Abstract:  Francisella tularensis genomes encode homologues of type IV pili. Though several F. tularensis genes required for Tfp expression are homologous to genes required for type II secretion (T2S), these gene clusters mainly bear structural signatures that are typical of Tfp. There is preliminary evidence that different F.
Ake, Forsberg, Tina, Guina
openaire   +2 more sources

Type IV pili facilitated natural competence in Fusobacterium nucleatum

Anaerobe, 2023
Many bacterial species naturally take up DNA from their surroundings and recombine it into their chromosome through homologous gene transfer (HGT) to aid in survival and gain advantageous functions. Herein we present the first characterization of Type IV pili facilitated natural competence in Fusobacterium nucleatum, which is a Gram-negative, anaerobic
Blake E. Sanders   +7 more
openaire   +2 more sources

Diversity, assembly and regulation of archaeal type IV pili-like and non-type-IV pili-like surface structures

Research in Microbiology, 2012
Archaea have evolved fascinating surface structures allowing rapid adaptation to changing environments. The archaeal surface appendages display such diverse biological roles as motility, adhesion, biofilm formation, exchange of genetic material and species-specific interactions and, in turn, increase fitness of the cells.
Lassak, Kerstin   +2 more
openaire   +4 more sources

Dynamics of gonococcal type IV pili during infection

ChemPhysChem, 2009
AbstractKeep that motor running: Type IV pili are among the strongest molecular motors characterized to date. Herein it is reported that pilus motors of the human pathogen Neisseria gonorrhoeae are very active for at least one day post‐infection of epithelial cells.
Dirk, Opitz   +2 more
openaire   +2 more sources

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