Results 1 to 10 of about 245,099 (255)
Molecular architecture of bacterial type IV secretion systems.
PLoS Pathogens, 2022 Bacterial type IV secretion systems (T4SSs) are a versatile group of nanomachines that can horizontally transfer DNA through conjugation and deliver effector proteins into a wide range of target cells.
Michael J Sheedlo +3 more
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Functional plasticity in the type IV secretion system of Helicobacter pylori. [PDF]
PLoS Pathogens, 2013 Helicobacter pylori causes clinical disease primarily in those individuals infected with a strain that carries the cytotoxin associated gene pathogenicity island (cagPAI).
Roberto M Barrozo +10 more
doaj +4 more sources
Campylobacter fetus Subspecies Contain Conserved Type IV Secretion Systems on Multiple Genomic Islands and Plasmids [PDF]
, 2016 Acknowledgments We like to thank Dr. John Devenish and Dr. Brian Brooks (Canadian Food Inspection Agency) for providing strains. We thank Nathaniel Simon and Mary Chapman for the generation of Illumina MiSeq reads and we thank James Bono for the ...
Duim, Birgitta +7 more
core +23 more sources
Secretion of Pertussis Toxin from Bordetella pertussis
Toxins, 2021 Production and secretion of pertussis toxin (PT) is essential for the virulence of Bordetella pertussis. Due to the large oligomeric structure of PT, transport of the toxin across bacterial membrane barriers represents a significant hurdle that the ...
Drusilla L. Burns
doaj +1 more source
The Missing Pieces: The Role of Secretion Systems in Campylobacter jejuni Virulence
Biomolecules, 2023 Campylobacter jejuni is likely the most common bacterial cause of gastroenteritis worldwide, responsible for millions of cases of inflammatory diarrhea characterized by severe abdominal cramps and blood in the stool. Further, C.
Amber D. Gabbert +7 more
doaj +1 more source
mLife, 2022 The mitochondrion is an important signaling hub that governs diverse cellular functions, including metabolism, energy production, and immunity. Among the hundreds of effectors translocated into host cells by the Dot/Icm system of Legionella pneumophila ...
Jiaqi Fu +6 more
doaj +1 more source
Type IV collagen reduces MUC5AC secretion in the lungs of ovalbumin-sensitized mice
Frontiers in Pharmacology, 2022 Mucin 5AC (MUC5AC) is excessively secreted in the respiratory tract of patients with asthma. Suppressing this secretion is important for improving the air passages, which facilitates easy breathing.
Jun Iwashita +3 more
doaj +1 more source
Primary architecture and energy requirements of Type III and Type IV secretion systems
Frontiers in Cellular and Infection Microbiology, 2023 Many pathogens use Type III and Type IV protein secretion systems to secrete virulence factors from the bacterial cytosol into host cells. These systems operate through a one-step mechanism. The secreted substrates (protein or nucleo-protein complexes in
Elena Cabezón +2 more
doaj +1 more source
Recruitment of heterologous substrates by bacterial secretion systems for transkingdom translocation
Frontiers in Cellular and Infection Microbiology, 2023 Bacterial secretion systems mediate the selective exchange of macromolecules between bacteria and their environment, playing a pivotal role in processes such as horizontal gene transfer or virulence.
Dolores L. Guzmán-Herrador +2 more
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Frontiers in Cellular and Infection Microbiology, 2020 Type IV secretion systems are protein secretion machineries that are frequently used by pathogenic bacteria to inject their virulence factors into target cells of their respective hosts.
Clara Lettl +16 more
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