Results 261 to 270 of about 490,629 (332)

Identification of VceA and VceC, two members of the VjbR regulon that are translocated into macrophages by the Brucella type IV secretion system

Molecular Microbiology, 2008
Maarten De Jong, Yao-Hui Sun, Andreas B. den Hartigh, J. V. van Dijl, R. Tsolis   +4 more
semanticscholar   +1 more source

High‐Throughput Generation of Tumor Spheroids via Droplet Microfluidics for siRNA‐Loaded Nanomedicine Assessment

Advanced Healthcare Materials, EarlyView.
A droplet microfluidic platform is employed to enable high‐throughput, uniform tumor spheroid generation for evaluating siRNA‐loaded nanomedicines at the protein level. As a proof of concept, breast (MCF‐7) and brain (U87 MG) cancer cell lines are investigated using this platform, revealing penetration profiles and therapeutic responses between the two
Ling Liu, Guoying Wang, Yang Zhang, Bingyang Shi, Ming Li   +4 more
wiley   +1 more source

Cryo-EM structure of a conjugative type IV secretion system suggests a molecular switch regulating pilus biogenesis. [PDF]

EMBO J
Macé K, Waksman G.
europepmc   +1 more source

Relationships between a new type IV secretion system and the icm/dot virulence system of Legionella pneumophila

Molecular Microbiology, 1999
G. Segal, J. Russo, H. Shuman
semanticscholar   +1 more source

Decellularized Extracellular Matrix (dECM) in Tendon Regeneration: A Comprehensive Review

Advanced Healthcare Materials, EarlyView.
Decellularized Extracellular Matrix (dECM) offers a promising solution by replicating the native tendon microenvironment and promoting regeneration. This review highlights advances in the decellularization methods, as well as their integration with emerging technologies and translational progress in tendon tissue engineering.
Kumaresan Sakthiabirami, Yeonwoo Park, Seong Kyeong Jo, Min Hee Kim, Jae Hwang Song   +4 more
wiley   +1 more source

Type IV secretion system effector sabotages multiple defense systems in a competing bacterium. [PDF]

ISME J
Wang B, Xu F, Zhang Z, Shen D, Wang L, Wu H, Yan Q, Cui C, Wang P, Wei Q, Shao X, Wang M, Qian G.   +12 more
europepmc   +1 more source

A quorum‐sensing regulator controls expression of both the type IV secretion system and the flagellar apparatus of Brucella melitensis

Cellular Microbiology, 2005
R. Delrue, C. Deschamps, S. Léonard, C. Nijskens, I. Danese, J. Schaus, S. Bonnot, J. Ferooz, A. Tibor, X. De Bolle, J. Letesson   +10 more
semanticscholar   +1 more source

SiO2‐CaOCME/Poly(Tetrahydrofuran)/Poly(Caprolactone) 3D‐Printed Scaffolds Drive Human‐Bone Marrow Stromal Cell Osteogenic Differentiation

Advanced Healthcare Materials, EarlyView.
3D printed hybrid scaffolds combining bioactive silica–calcium chemistry with elastic polymers guide human bone stem cells to form bone. The scaffolds support cell survival, organization, and invasion while releasing osteogenic ions. Together, architecture and composition drive bone‐specific gene expression, extracellular matrix organization, and ...
David R. Sory, Agathe C.M. Heyraud, Julian R. Jones, Sara M. Rankin   +3 more
wiley   +1 more source

IcmS‐dependent translocation of SdeA into macrophages by the Legionella pneumophila type IV secretion system

Molecular Microbiology, 2005
J. P. Bardill, Jennifer L. Miller, Joseph P. Vogel   +2 more
semanticscholar   +1 more source

Targeting the ARRDC3–DRP1 Axis via hUMSC‐Derived Exosomal CRYAB for Neuroprotection in Cerebral Ischemia/Reperfusion Injury

Advanced Healthcare Materials, EarlyView.
Intranasally administered hUMSC‐derived exosomes modulate the CRYAB–ARRDC3–Drp1 axis, alleviating mitochondrial dysfunction and ferroptosis, enhancing neuronal survival, reducing oxidative stress, and promoting functional recovery in ischemia‐reperfusion injury, offering a promising therapeutic strategy for ischemic stroke.
Rong ji, Zengyu Zhang, Zhuohang Liu, Kaicheng Yang, Xueyu Mao, Min Chu, Yong Wang, Jing Zhao   +7 more
wiley   +1 more source