Subversion of host cell signaling: The arsenal of Rickettsial species
Frontiers in Cellular and Infection Microbiology, 2022 Rickettsia is a genus of nonmotile, Gram-negative, non-spore-forming, highly pleomorphic bacteria that cause severe epidemic rickettsioses. The spotted fever group and typhi group are major members of the genus Rickettsia.
Dan Huang +3 more
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Xanthomonas campestris pv. campestris (cause of black rot of crucifers) in the genomic era is still a worldwide threat to brassica crops [PDF]
, 2012 Background Xanthomonas campestris pv. campestris (Xcc) (Pammel) Dowson is a Gram-negative bacterium that causes black rot, the most important disease of vegetable brassica crops worldwide. Intensive molecular investigation of Xcc is gaining momentum and
Holub, E. B., Vicente, Joana G.
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Polar delivery of Legionella type IV secretion system substrates is essential for virulence [PDF]
, 2017 A recurrent emerging theme is the targeting of proteins to subcellular microdomains within bacterial cells, particularly to the poles. In most cases, it has been assumed that this localization is critical to the protein’s function. Legionella pneumophila
Chang, Yi-Wei +4 more
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Frontiers in Microbiology, 2014 The plant tumor disease, known as crown gall, was not called by that name until more recent times. Tumors on plants, particularly on cultivated grapevines, were observed thousands of years ago and recorded in the bible (wine was being made 7000 years ...
Clarence I. Kado
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The intricate dance: host autophagy and Coxiella burnetii infection
Frontiers in Microbiology, 2023 Q fever is a zoonotic disease caused by Coxiella burnetii, an obligatory intracellular bacterial pathogen. Like other intracellular pathogens, C. burnetii is able to survive and reproduce within host cells by manipulating host cellular processes.
Tingting Wang +3 more
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Medically relevant Acinetobacter species require a type II secretion system and specific membrane-associated chaperones for the export of multiple substrates and full virulence [PDF]
, 2016 Acinetobacter baumannii, A. nosocomialis, and A. pittii have recently emerged as opportunistic human pathogens capable of causing severe human disease; however, the molecular mechanisms employed by Acinetobacter to cause disease remain poorly understood.
Feldman, Mario F +4 more
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Structure of a Type IV Secretion System Core Complex [PDF]
Science, 2009 Type IV secretion systems (T4SSs) are important virulence factors used by Gram-negative bacterial pathogens to inject effectors into host cells or to spread plasmids harboring antibiotic resistance genes. We report the 15 angstrom resolution cryo–electron microscopy structure of the core complex of a T4SS. The core complex is composed of three proteins,
Rémi, Fronzes +5 more
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AtlasT4SS: A curated database for type IV secretion systems [PDF]
BMC Microbiology, 2012 Abstract Background The type IV secretion system (T4SS) can be classified as a large family of macromolecule transporter systems, divided into three recognized sub-families, according to the well-known functions. The major sub-family is the conjugation system, which allows transfer of genetic material, such as a ...
Souza Rangel C +7 more
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Structure of a bacterial type IV secretion core complex at subnanometre resolution [PDF]
, 2013 Type IV secretion (T4S) systems are able to transport DNAs and/or proteins through the membranes of bacteria. They form large multiprotein complexes consisting of 12 proteins termed VirB1-11 and VirD4.
Chandran, Vidya +10 more
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Type IV secretion systems: Advances in structure, function, and activation [PDF]
Molecular Microbiology, 2021 AbstractBacterial type IV secretion systems (T4SSs) are a functionally diverse translocation superfamily. They consist mainly of two large subfamilies: (i) conjugation systems that mediate interbacterial DNA transfer and (ii) effector translocators that deliver effector macromolecules into prokaryotic or eukaryotic cells.
Tiago R. D. Costa +5 more
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