Results 61 to 70 of about 490,629 (332)

Biological and Structural Diversity of Type IV Secretion Systems [PDF]

Microbiology Spectrum, 2019
ABSTRACT The bacterial type IV secretion systems (T4SSs) are a functionally diverse superfamily of secretion systems found in many species of bacteria. Collectively, the T4SSs translocate DNA and monomeric and multimeric protein substrates to bacterial and eukaryotic cell types.
Yang Grace, Li, Bo, Hu, Peter J, Christie   +2 more
openaire   +2 more sources

A comparison of fourteen fully characterized mammalian-associated Campylobacter fetus isolates suggests that loss of defense mechanisms contribute to high genomic plasticity and subspecies evolution [PDF]

PeerJ, 2021
Campylobacter fetus is currently classified into three main subspecies, but only two of these, C. fetus subspecies fetus and C. fetus subsp. venerealis originate principally from ruminants where they inhabit different niches and cause distinct ...
Susan A. Nadin-Davis, John Chmara, Catherine D. Carrillo, Kingsley Amoako, Noriko Goji, Marc-Olivier Duceppe, John Devenish   +6 more
doaj   +2 more sources

Structural studies of T4S systems by electron microscopy [PDF]

, 2015
: Type IV secretion (T4S) systems are large dynamic nanomachines that transport DNA and/or proteins through the membranes of bacteria. Analysis of T4S system architecture is an extremely challenging task taking into account their multi protein ...
Abdallah AM, Gey van Pittius NC, Champion PA, et a, Backert S, Meyer TF, Bailey S, Ward D, Middleton R, et al., Banta LM, Kerr JE, Cascales E, et al., Cascales E, Cascales E, Christie PJ, Cascales E, Christie PJ, Christie PJ, Atmakuri K, Krishnamoorthy V, et al., Christie PJ, Cascales E, Clemens DL, Ge P, Lee BY, et al., Cornelis GR, Van Gijsegem F, De Carlo S, Harris JR, de Jong MF, Sun YH, den Hartigh AB, et al., Dubochet J, Durand E, Waksman G, Receveur-Brechot V, Eisenbrandt R, Kalkum M, Lai EM, et al., Filloux A, Fronzes R, Christie PJ, Waksman G, Fronzes R, Schafer E, Wang L, et al., Gomis-Ruth FX, Moncalian G, Perez-Luque R, et al., Henderson IR, Navarro-Garcia F, Desvaux M, et al., Hofreuter D, Karnholz A, Haas R, Jakubowski SJ, Kerr JE, Garza I, et al., Jakubowski SJ, Krishnamoorthy V, Cascales E, et al, Judd PK, Mahli D, Das A, Kerr JE, Christie PJ, Kudryashev M, Wang RY, Brackmann M, et al., Lederberg J, Tatum EL, Lessl M, Lanka E, Li X, Mooney P, Zheng S, et al., Llosa M, de la Cruz F, Low HH, Gubellini F, Rivera-Calzada A, et al., McMullan G, Faruqi AR, Henderson R, et al., Mossey P, Hudacek A, Das A, Ninio S, Roy CR, Orlova EV, Saibil HR, Pansegrau W, Lanka E, Pena A, Matilla I, Martin-Benito J, et al., Ripoll-Rozada J, Zunzunegui S, de la Cruz F, et al, Rivera-Calzada A, Fronzes R, Savva CG, et al., Savvides SN, Yeo HJ, Beck MR, et al., Schraidt O, Marlovits TC, Schroder G, Krause S, Zechner EL, et al., Sivanesan D, Baron C, Terradot L, Bayliss R, Oomen C, et al., Trokter M, Felisberto-Rodrigues C, Christie PJ, et, Wallden K, Williams R, Yan J, et al., Yeo HJ, Savvides SN, Herr AB, et al., Yeo HJ, Yuan Q, Beck MR, et al., Yuan Q, Carle A, Gao C, et al., Zechner EL, Lang S, Schildbach JF   +50 more
core   +2 more sources

Crystal structure of the type IV secretion system component CagX from Helicobacter pylori. [PDF]

, 2018
This is the final version.Available from the International Union of Crystallography via the DOI in this record.Helicobacter pylori, a Gram-negative bacterial pathogen prevalent in the human population, is the causative agent of severe gastric diseases ...
Fan, F, Isupov, MN, Keegan, RM, Liu, Y, Sun, L, Wu, Y, Zhang, J, Zhao, Y   +7 more
core   +1 more source

Cryo-EM reveals species-specific components within the Helicobacter pylori Cag type IV secretion system core complex

bioRxiv, 2020
The pathogenesis of Helicobacter pylori-associated gastric cancer is dependent on delivery of CagA into host cells through a type IV secretion system (T4SS). The H.
M. Sheedlo, J. Chung, N. Sawhney, C. Durie, T. Cover, T. Cover, M. Ohi, M. Ohi, D. Lacy   +8 more
semanticscholar   +1 more source

Cag type IV secretion system: CagI independent bacterial surface localization of CagA. [PDF]

PLoS ONE, 2013
Helicobacter pylori Cag type IV secretion system (Cag-T4SS) is a multi-component transporter of oncoprotein CagA across the bacterial membranes into the host epithelial cells. To understand the role of unique Cag-T4SS component CagI in CagA translocation,
Navin Kumar, Mohd Shariq, Rajesh Kumari, Rakesh K Tyagi, Gauranga Mukhopadhyay   +4 more
doaj   +1 more source

The opportunistic pathogen Stenotrophomonas maltophilia utilizes a type IV secretion system for interbacterial killing

bioRxiv, 2019
Bacterial type IV secretion systems (T4SS) are a highly diversified but evolutionarily related family of macromolecule transporters that can secrete proteins and DNA into the extracellular medium or into target cells.
Ethel Bayer-Santos, William Cenens, B. Matsuyama, G. Sessa, Izabel Del Valle Mininel, C. Farah   +5 more
semanticscholar   +1 more source

Structural and functional diversity of type IV secretion systems

Nature Reviews Microbiology, 2023
Considerable progress has been made in recent years in the structural and molecular biology of type IV secretion systems in Gram-negative bacteria. The latest advances have substantially improved our understanding of the mechanisms underlying the recruitment and delivery of DNA and protein substrates to the extracellular environment or target cells. In
Costa, Tiago, Patkowski, Jonasz, Macé, Kévin, J. Christie, Peter, Waksman, Gabriel   +4 more
openaire   +4 more sources

Draft genome sequence for virulent and avirulent strains of Xanthomonas arboricola isolated from Prunus spp. in Spain [PDF]

, 2016
Xanthomonas arboricola is a species in genus Xanthomonas which is mainly comprised of plant pathogens. Among the members of this taxon, X. arboricola pv.
Cubero, Jaime, Garita Cambronero, J., López, María M., Palacio Bielsa, Ana   +3 more
core   +1 more source

Secretion of Pertussis Toxin from Bordetella pertussis

Toxins, 2021
Production and secretion of pertussis toxin (PT) is essential for the virulence of Bordetella pertussis. Due to the large oligomeric structure of PT, transport of the toxin across bacterial membrane barriers represents a significant hurdle that the ...
Drusilla L. Burns
doaj   +1 more source