Structure of a translocation signal domain mediating conjugative transfer by Type IV secretion systems [PDF]
, 2013 Relaxases are proteins responsible for the transfer of plasmid and chromosomal DNA from one bacterium to another during conjugation. They covalently react with a specific phosphodiester bond within DNA origin of transfer sequences, forming a nucleo ...
Gruber, C.J. +7 more
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Legionella pneumophila strain 130b possesses a unique combination of type IV secretion systems and novel Dot/Icm secretion system effector proteins [PDF]
, 2010 Legionella pneumophila is a ubiquitous inhabitant of environmental water reservoirs. The bacteria infect a wide variety of protozoa and, after accidental inhalation, human alveolar macrophages, which can lead to severe pneumonia. The capability to thrive
Beatson, Scott A. +13 more
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Unveiling Molecular Scaffolds of the Type IV Secretion System [PDF]
Journal of Bacteriology, 2004 In gram-negative bacteria, secretion of macromolecules across the two membranes takes place using diverse macromolecular transport assemblies, from simple one-component systems to complex multicomponent machineries.
Yeo, Hye-Jeong, Waksman, Gabriel
openaire +3 more sources
Identification of a system required for the functional surface localization of sugar binding proteins with class III signal peptides in Sulfolobus solfataricus [PDF]
, 2007 The hyperthermophilic archaeon Sulfolobus solfataricus contains an unusual large number of sugar binding proteins that are synthesized as precursors with a class III signal peptide.
Albers S.V. +12 more
core +10 more sources
Bartonella taylorii: A Model Organism for Studying Bartonella Infection in vitro and in vivo
Frontiers in Microbiology, 2022 Bartonella spp. are Gram-negative facultative intracellular pathogens that infect diverse mammals and cause a long-lasting intra-erythrocytic bacteremia in their natural host. These bacteria translocate Bartonella effector proteins (Beps) into host cells
Katja Fromm +9 more
doaj +1 more source
The PAS domain-containing histidine kinase RpfS is a second sensor for the diffusible signal factor of Xanthomonas campestris [PDF]
, 2014 Summary: A cell-cell signalling system mediated by the fatty acid signal DSF controls the virulence of Xanthomonas campestris pv. campestris (Xcc) to plants. The synthesis and recognition of the DSF signal depends upon different Rpf proteins.
Allan, John H. +5 more
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In Situ Molecular Architecture of the Helicobacter pylori Cag Type IV Secretion System
mBio, 2019 Bacterial type IV secretion systems (T4SSs) have been phylogenetically grouped into two subfamilies. The T4ASSs, represented by the Agrobacterium tumefaciens VirB/VirD4T4SS, include “minimized” machines assembled from 12 VirB- and VirD4-like subunits and
Bo Hu +7 more
semanticscholar +1 more source
Biological Diversity and Evolution of Type IV Secretion Systems [PDF]
, 2017 The bacterial type IV secretion systems (T4SSs) are a highly functionally and structurally diverse superfamily of secretion systems found in many species of Gram-negative and -positive bacteria. Collectively, the T4SSs can translocate DNA and monomeric and multimeric protein substrates to a variety of bacterial and eukaryotic cell types.
Christie, Peter +2 more
openaire +3 more sources
CagI is an essential component of the Helicobacter pylori Cag type IV secretion system and forms a complex with CagL. [PDF]
PLoS ONE, 2012 Helicobacter pylori, the causative agent of type B gastritis, peptic ulcers, gastric adenocarcinoma and MALT lymphoma, uses the Cag type IV secretion system to induce a strong proinflammatory response in the gastric mucosa and to inject its effector ...
Kieu Thuy Pham +5 more
doaj +1 more source
Oncogene, 2016 Helicobacter pylori (H. pylori) is the strongest identified risk factor for gastric cancer, the third most common cause of cancer-related death worldwide. An H. pylori constituent that augments cancer risk is the strain-specific cag pathogenicity island,
Matthew G. Varga +16 more
semanticscholar +1 more source