Results 201 to 210 of about 4,835,960 (268)

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch, Isabel Vogel, Sina Nokodian, Johanna Moeller, Antonia Blechschmidt, Vicky Hecht, Vanessa Kuentzel, Katharina Thiedig, Melissa Schwab, Oliver Schilling, Holger Bronger, Marion Kiechle, Viktor Magdolen, Tobias Dreyer   +13 more
wiley   +1 more source

Which Adverse and Positive Childhood Experiences are most Strongly Associated with Young Peoples' Arrests and Convictions? [PDF]

Advers Resil Sci
La Charite J, Schickedanz A, Biely C, Dudovitz R, Guerrero AD, Leifheit KM, Marinello A, Meza BPL, Russ S, Sastry N, Slavich GM, Barnert ES.   +11 more
europepmc   +1 more source

Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma

Molecular Oncology, EarlyView.
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic, Anne Nørremølle, Lilian Bomme Ousager, Lars van Brakel Andersen, Marie Louise Mølgaard Binderup, Mads Thomassen   +5 more
wiley   +1 more source

Single-nucleus atlas provides insights into changes in the evolution of the pig hippocampus. [PDF]

BMC Biol
Xu L, Jiang J, Zhuang Y, Wei X, Xie Q, Yu P, Liu S, Cao C, Sun J, Gu J, Zhang Z, Zhao W, Zhang Z, Wang Q, Pan Y, Wang Z.   +15 more
europepmc   +1 more source

Totipotency and high plasticity in an embryo with an invariant, fate-specifying cleavage program. [PDF]

Curr Biol
Rock AQ, Srivastava M.
europepmc   +1 more source

An entropic measure of diverse specialization highlights multifunctional neurons in annotated connectomes. [PDF]

Netw Neurosci
Moon SS, Ripoll-Sánchez L, Vértes P, Schafer WR, Ahnert SE.   +4 more
europepmc   +1 more source

NetG2P: Network-based genotype-to-phenotype transformation identifies key signaling crosstalk for prognosis in pan-cancer study. [PDF]

BMC Biol
Lee J, Jang SW, Lee B, Shin J, Gong JR, Shin D.   +5 more
europepmc   +1 more source

Analysis of RNA Expression Specificity and Commonality in Commonly Used Tool Cells and Multiple Tissues of Pigs. [PDF]

Biomolecules
Yang H, Zhang C, Chao X, Chen J, Ding Y, Zhou B.   +5 more
europepmc   +1 more source

Single-cell transcriptomic analysis reveals intra-tumoral heterogeneity and immunotherapy strategies in high-grade serous ovarian cancer. [PDF]

iScience
Gao C, Lv X, Pan A, Chen L, Liu Q, Zhang D, Wu W.   +6 more
europepmc   +1 more source