Results 141 to 150 of about 221,229 (313)

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola   +11 more
wiley   +1 more source

Soil map, Texas, Victoria County

open access: yes, 1931
Map displays soil types along with creeks, lakes, rivers, towns, schools, roads, railroads, and ranches.
Texas Agricultural Experiment Station   +1 more
core  

In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

open access: yesMolecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq   +8 more
wiley   +1 more source

Soil map, Texas, Bee County

open access: yes, 1938
Map displays soil types along with creeks, towns, schools, churches, power transmission lines, oil and gas pipelines, roads, and railroads. Includes legend and symbols.
Texas Agricultural Experiment Station   +1 more
core  

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

open access: yesFEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point   +7 more
wiley   +1 more source

Applicability of mitotic figure counting by deep learning: a development and pan‐cancer validation study

open access: yesFEBS Open Bio, EarlyView.
In this study, we developed a deep learning method for mitotic figure counting in H&E‐stained whole‐slide images and evaluated its prognostic impact in 13 external validation cohorts from seven different cancer types. Patients with more mitotic figures per mm2 had significantly worse patient outcome in all the studied cancer types except colorectal ...
Joakim Kalsnes   +32 more
wiley   +1 more source

DSpace como herramienta para un repositorio de documentos administrativos en la Universidad Nacional Experimental del Táchira

open access: yesRevista Interamericana de Bibliotecología, 2013
The administrative digital document repositories allow an organization or institution to manage an automated production. This article aims to describe, roughly, a proposal to implement a Repository Administrative Documents in The Universidad Nacional ...
Jose Texier   +4 more
doaj  

Chameleon sequences reveal structural effects in proteins representing micelle‐like distribution of hydrophobicity

open access: yesFEBS Open Bio, EarlyView.
Amino acids sequence of two different proteins with the same sequence (chameleon sequence—black boxes) represent in 3D structure of the proteins different secondary structures: HHHH—helical and BBB—Beta‐structural. The chains folded in water environment adopt different III‐order structures in which the chameleon fragments appear to adopt similar status
Irena Roterman   +4 more
wiley   +1 more source

Salary standardization for the types and positions of employment in the state eleemosynary and penal institutions of the state of Oregon

open access: yes, 1935
Prepared in cooperation with the Budget Division.Typescript.Title from PDF cover (viewed on July 11, 2017).This archived document is maintained by the State Library of Oregon as part of the Oregon Documents Depository Program.

core  

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