Results 131 to 140 of about 168,919,123 (296)

CEACAM1 participation in breast cancer progression

Molecular Oncology, EarlyView.
In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin, Irina Kube‐Golovin, Anatolii Romaniuk, Gunther Wennemuth   +3 more
wiley   +1 more source

INFORMATION SYSTEM OF AUTOMATION OF PREPARATION EDUCATIONAL PROCESS DOCUMENTS

Системный анализ и прикладная информатика, 2016
Information technology is rapidly conquering the world, permeating all spheres of human activity. Education is not an exception. An important direction of information of education is the development of university management systems.
V. A. Matyushenko, V. U. Filon, N. I. Beloded   +2 more
doaj  

OpenITI MAKHZAN: An Open Annotated Dataset of Arabic, Persian, Ottoman Turkish, and Urdu Print and Manuscript Data

Journal of Open Humanities Data
The OpenITI MAKHZAN dataset is a large aggregation of Arabic-script ground truth and evaluation data drawn from a wide variety of Persian, Arabic, Ottoman Turkish, and Urdu scribal print and handwritten (manuscript) documents.
Jonathan Parkes Allen, John Mullan, Lorenz Nigst, Mathew Barber, Taimoor Shahid-Khan, Masoumeh Seydi, Danlu Chen, Yufei Weng, Nikolai Vogler, Jacob Murel, Osama Eshera, Taylor Berg-Kirkpatrick, David Smith, Sarah Bowen Savant, Matthew Thomas Miller   +14 more
doaj   +1 more source

Partial FAK suppression promotes tumor growth, an effect reversed by macrophage p110δ PI3K inactivation

Molecular Oncology, EarlyView.
Partial inhibition of focal adhesion kinase (FAK) can paradoxically promote tumor growth, rather than simply producing a weaker antitumor effect than that observed with strong FAK suppression. In breast cancer and melanoma models, targeting p110δ PI3K, particularly in macrophages, counteracted these tumor‐promoting effects, highlighting the importance ...
Lydia Xenou, Niki Tzenaki, Anna Tsapara, Maria Tzardi, Evangelia A. Papakonstanti   +4 more
wiley   +1 more source

Arrangement of Regulatory and Standardization Documents Used in Russian Organizations

Экономика и управление, 2019
Aim. This study aims to systematize regulatory documents used in organizations and classify them based on one of the fundamental categories of regulatory documents, i.e., standardization documents. Tasks. This study aims to provide a brief description of
Irina I. Antonova, Vitaliy A. Smirnov, Alsu T. Khadieva   +2 more
doaj  

Identifying reusable abstract data types in code [PDF]

, 1994
The basic aim of this thesis is to analyse the state of the art in the field of the software reuse Software reuse is widely regarded as offering the opportunity for improving the software production process.
Tortorella, Maria
core  

Profiling neoadjuvant therapy response in rectal cancer using meta‐analysis of publicly available transcriptomic RNA‐seq datasets

Molecular Oncology, EarlyView.
This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic, Rafael Stroggilos, Mladen Marinkovic, Ana Djuric, Suzana Stojanovic‐Rundic, Radmila Jankovic, Sergi Castellvi‐Bel, Remond J.A. Fijneman, Antonia Vlahou, Jerome Zoidakis, Milena Cavic   +10 more
wiley   +1 more source

The VHL tumor suppressor at the crossroad of protein folding, aggregation, and cancer

Molecular Oncology, EarlyView.
Mutations, environmental stress, and chaperone dysfunction can destabilize pVHL, promoting its conversion from the native folded state into amyloid‐like assemblies. This transition may contribute to protein storage, cell dormancy, survival, and drug resistance.
Lara Abad, Silvio Carlo Ermanno Tosatto, Emanuela Leonardi   +2 more
wiley   +1 more source

Documents outlining the personnel around which the regiments in Havana, Cuba, are organized.

Documents outlining the personnel around which the regiments in Havana, Cuba, are organized. Includes a rough list of types of personnel.
Unknown author
core  

Patrimoni Audiovisual : l'evolució del document audiovisual i la problemàtica que genera [PDF]

, 2018
Els documents audiovisuals són un tipus de documentació relativament nou, tenint en compte que comencen a aparèixer al segle XIX amb les primeres imatges en moviment, no tenen la llarga trajectòria dels documents textuals.
Universitat Autònoma de Barcelona. Escola Superior d'Arxivística i Gestió de Documents, Escariz Torres, Carla   +1 more
core