Results 41 to 50 of about 221,229 (313)
Новые исследования ТувыAt the present time, electronic publication of archival documents is a modern high-profile way to use them and satisfy information needs of the society and researchers, as well as to popularize the documentary heritage.
Гульназия Толгаевна Жакупова +3 more
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Interactive Documents: Language Features and Document Status
Вестник Волгоградского государственного университета: Серия 2. Языкознание, 2021 The research is carried out in line with the current problems of modern document linguistics, related to the study of formation peculiarities, design and functioning of new types of documents.
Elena Belous
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Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
FEBS Letters, EarlyView.This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
FEBS Letters, EarlyView.The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source
Electronic evidence in Russian criminal proceedings: problematic aspects
Юридический вестник Самарского университетаThe article discusses some problematic aspects related to the use of electronic evidence in evidence. The ambiguity of scientists’ approaches to the question of what place this type of evidence occupies in the evidence system available in the criminal ...
S. V. Kornakova, E. V. Chigrina
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JMIR Medical InformaticsBackgroundNatural language processing (NLP) techniques can be used to analyze large amounts of electronic health record texts, which encompasses various types of patient information such as quality of life, effectiveness of ...
Tomohiro Nishiyama +11 more
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FEBS Letters, EarlyView.We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source
FAMILY PRESERVATION SERVICES: TYPES OF SERVICES RENDERED BY SOCIAL WORKERS TO AT-RISK FAMILIES
Social Work/Maatskaplike Werk, 2012 Family preservation services are considered essential in order to avoid the removal of children from their families. In accordance with South African legislation and policy documents, social workers at family welfare organisations must focus on family ...
Marianne Strydom
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FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
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Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source