Results 81 to 90 of about 2,733,713 (347)

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

FEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson, Mackenzie K Herroon, Shane Mecca, Laimar C Garmo, Jacob Lindquist, Shrila Rajendran, Steve M. Patrick, Izabela Podgorski   +7 more
wiley   +1 more source

Short and long-term effectiveness of couple counselling: a study protocol

BMC Public Health, 2012
Background Healthy couple relationships are fundamental to a healthy society, whereas relationship breakdown and discord are linked to a wide range of negative health and wellbeing outcomes.
Schofield Margot J, Mumford Nicholas, Jurkovic Dubravko, Jurkovic Ivancica, Bickerdike Andrew   +4 more
doaj   +1 more source

Under-Utilization of Community Health Centers in Purworejo Regency, Central Java [PDF]

, 2006
The basic strategy of the Ministry of Health to achieve Health For All In Indonesia 2010 is through health paradigm, decentralization, professionalism and health service management.
Triratnawati, A. (Atik)
core   +1 more source

Having a family doctor was associated with lower utilization of hospital-based health services

BMC Health Services Research, 2015
BackgroundPrimary care in the United States and most countries in Asia are provided by a variety of doctors. However, effectiveness of such diversified primary care in gate-keeping secondary medical services is unknown.
Colman S. C. Fung, Carlos K. H. Wong, D. Fong, Albert Lee, C. Lam   +4 more
semanticscholar   +1 more source

PARP inhibitors elicit distinct transcriptional programs in homologous recombination competent castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham, Jasibel Vasquez‐Gonzalez, Samantha M. Barnada, Salome Tchotorlishvili, Latese Jones, Ryan Maguire, Genevieve Lewis, Kinza Rizwan, Jenny Deng, Salma Koachar, Drithi Patel, Hailey Shankle, Tessa Mulders, Namra Ajmal, Charalambos Solomides, Emad S. Alnemri, Teresa F. Alnemri, Ayesha A. Shafi, Leonard G. Gomella, Wm Kevin Kelly, Steven B. McMahon, Matthew J. Schiewer   +21 more
wiley   +1 more source

Preference for Community Health Services of Patients with Multimorbidity [PDF]

Zhongguo quanke yixue
Background As aging process continues to accelerate in China, multimorbidity have become a major public problem that threatens the health of the entire population.
WEI Lifang, ZHANG Ling, TAN Ya, LUO Xiu
doaj   +1 more source

Challenges in maintaining treatment services for people who use drugs during the COVID-19 pandemic

Harm Reduction Journal, 2020
The impact of COVID-19 across health services, including treatment services for people who use drugs, is emerging but likely to have a high impact. Treatment services for people who use drugs provide essential treatment services including opiate agonist ...
A. Dunlop, B. Lokuge, D. Masters, Marcia Sequeira, P. Saul, G. Dunlop, J. Ryan, Michelle Hall, Nadine Ezard, P. Haber, N. Lintzeris, L. Maher   +11 more
semanticscholar   +1 more source

Characterizing the salivary RNA landscape to identify potential diagnostic, prognostic, and follow‐up biomarkers for breast cancer

Molecular Oncology, EarlyView.
This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan, Irina Primac, Emre Etlioglu, Laurens Debruyne, Ann Janssen, Magy Sallam, Kevin Tabury, Roel Quintens, Wiebren Tjalma, Mohammed Abderrafi Benotmane   +9 more
wiley   +1 more source

Impact of Health Insurance Type on the Quality of Hemodialysis Services: A Multilevel Analysis

Journal of Preventive Medicine and Public Health, 2010
This study aims to compare quality indicators for the hemodialysis services between patients with health insurance and those with medical aid.This study used data from sampled hospitals that provided a hemodialysis service. A total of 2,287 patients were selected, and the information for hemodialysis service has been granted from medical record reviews.
Jin Hee, Jung, Soon Man, Kwon, Kyoung Hoon, Kim, Seon Kyoung, Lee, Dong Sook, Kim   +4 more
openaire   +2 more sources

Adenosine‐to‐inosine editing of miR‐200b‐3p is associated with the progression of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
A‐to‐I editing of miRNAs, particularly miR‐200b‐3p, contributes to HGSOC progression by enhancing cancer cell proliferation, migration and 3D growth. The edited form is linked to poorer patient survival and the identification of novel molecular targets.
Magdalena Niemira, Anna Skwarska, Karolina Chwialkowska, Agnieszka Ostrowska, Gabriela Sokolowska, Anna Zeller, Anna Erol, Andrzej Eljaszewicz, Bartosz Hanczaruk, Anna Michalska‐Falkowska, Agnieszka Tarasik, Joanna Reszec‐Gielazyn, Pawel Knapp, Marcin Moniuszko, Adam Kretowski   +14 more
wiley   +1 more source