Results 1 to 10 of about 608,278 (199)
Leiomyoadenomatoid tumors: A type of rare benign epididymal tumor
Urology Case Reports, 2021 Primary tumors of the epididymis are mostly benign in nature, and the most common type is adenomatoid tumors followed by leiomyomas. Leiomyoadenomatoid tumors are very rare benign epididymal neoplasms composed of two components: gland-like structures lined by cuboidal cells and bundles of smooth muscle components.
Nasser Almohaya +4 more
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Brain tumors in neurofibromatosis type 1 [PDF]
Neuro-Oncology Advances, 2019 AbstractAbstractAs a cancer predisposition syndrome, individuals with neurofibromatosis type 1 (NF1) are at increased risk for the development of both benign and malignant tumors. One of the most common locations for these cancers is the central nervous system, where low-grade gliomas predominate in children.
Amanda De Andrade Costa, David H Gutmann
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Salivary Gland-type Tumors of the Lung [PDF]
Archives of Pathology & Laboratory Medicine, 2021 Context.—Salivary gland-type tumors (SGTs) of the lung represent a distinct group of lung neoplasms. Pulmonary SGTs often pose diagnostic challenges, especially in small biopsy and cytology samples because of limited sample volume and overlapping morphology among pulmonary SGTs, metastatic SGTs of head and neck origin, and other lung tumors.Objective ...
Syed M. Gilani +3 more
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A NAIL TUMOR OF UNUSUAL TYPE [PDF]
Archives of Dermatology and Syphilology, 1922 In January, 1921, while delivering a clinical lecture before the Douglas County Medical Society, at Lawrence, Kansas, I encountered a case of nail disorder which was entirely new to me. REPORT OF CASES Case 1.— The patient was a young woman, under the care of my friend, Dr. H. L. Chambers, and the affection, which involved the nail of the left thumb,
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Adult‐type granulosa cell tumor: An unusual testicular tumor [PDF]
Clinical Case Reports, 2021 AbstractAdult type granulosa cell tumours are extremely rare. Albeit mostly benign, 10% have malignant potential associated with unfavorable pathological features. The present case with the longest history duration, shows that size alone may not necessarily be unfavorable prognosticator when not associated with other factors.
Alain Mwamba Mukendi +3 more
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Molecular classification of multiple tumor types [PDF]
Bioinformatics, 2001 Abstract Using gene expression data to classify tumor types is a very promising tool in cancer diagnosis. Previous works show several pairs of tumor types can be successfully distinguished by their gene expression patterns (Golub et al. 1999, Ben-Dor et al. 2000, Alizadeh et al. 2000).
Sridhar Ramaswamy +9 more
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The dual nature of TDC – bridging dendritic and T cells in immunity
FEBS Letters, EarlyView.TDC are hematopoietic cells combining dendritic and T cell features. They reach secondary lymphoid organs (SLOs) and peripheral organs (liver and lungs) after FLT3‐dependent development in the bone marrow and maturation in the thymus. TDC are activated and enriched in SLOs upon viral infection, suggesting that they might play unique immune roles, since
Maria Nelli, Mirela Kuka
wiley +1 more source
FoxO1 signaling in B cell malignancies and its therapeutic targeting
FEBS Letters, EarlyView.FoxO1 has context‐specific tumor suppressor or oncogenic character in myeloid and B cell malignancies. This includes tumor‐promoting properties such as stemness maintenance and DNA damage tolerance in acute leukemias, or regulation of cell proliferation and survival, or migration in mature B cell malignancies.
Krystof Hlavac +3 more
wiley +1 more source
FEBS Letters, EarlyView.Metabolic dysfunction‐associated steatotic liver disease (MASLD) affects nearly one‐third of the global population and poses a significant risk of progression to cirrhosis or liver cancer. Here, we discuss the roles of hepatic dendritic cell subtypes in MASLD, highlighting their distinct contributions to disease initiation and progression, and their ...
Camilla Klaimi +3 more
wiley +1 more source
Insights into PI3K/AKT signaling in B cell development and chronic lymphocytic leukemia
FEBS Letters, EarlyView.This Review explores how the phosphoinositide 3‐kinase and protein kinase B pathway shapes B cell development and drives chronic lymphocytic leukemia, a common blood cancer. It examines how signaling levels affect disease progression, addresses treatment challenges, and introduces novel experimental strategies to improve therapies and patient outcomes.
Maike Buchner
wiley +1 more source