A Landscape of Metabolic Variation across Tumor Types [PDF]
Tumor metabolism is reorganized to support proliferation in the face of growth-related stress. Unlike the widespread profiling of changes to metabolic enzyme levels in cancer, comparatively less attention has been paid to the substrates/products of enzyme-catalyzed reactions, small-molecule metabolites.
Ed, Reznik +8 more
openaire +2 more sources
Cannabinoid receptor CB2 drives HER2 pro-oncogenic signaling in breast cancer [PDF]
Pharmacological activation of cannabinoid receptors elicits antitumoral responses in different models of cancer. However, the biological role of these receptors in tumor physio-pathology is still unknown.
Alkatout, Ibrahim +31 more
core +1 more source
Integrative analysis of the inter-tumoral heterogeneity of triple-negative breast cancer. [PDF]
Triple-negative breast cancers (TNBC) lack estrogen and progesterone receptors and HER2 amplification, and are resistant to therapies that target these receptors.
Boymoushakian, Lari +3 more
core
Isolation of three novel rat and mouse papillomaviruses and their genomic characterization. [PDF]
Despite a growing knowledge about the biological diversity of papillomaviruses (PV), only little is known about non-human PV in general and about PV mice models in particular.
Gottschling, Marc +5 more
core +4 more sources
Vascular endothelial growth factor production and regulation in rodent and human pituitary tumor cells in vitro [PDF]
Angiogenesis, the formation of a new blood supply, is an essential step in tumorigenesis. Although vascular endothelial growth factor (VEGF) is known to be a very potent angiogenic factor in most solid tumors, little is known about its production and ...
Gloddek, Jutta +7 more
core +1 more source
[Types of tumor cells movement].
Problems in successful cancer therapy result from an adaptive character and high plasticity in tumor cells behaviour. Their accommodation to a differentiated environment is preceded by an alteration in expression profile of several proteins. Three types of tumor cell migration were characterized so far: mezenchymal, ameboid and collective.
Agnieszka, Popow-Woźniak +2 more
openaire +1 more source
Noninvasive depth estimation using tissue optical properties and a dual-wavelength fluorescent molecular probe in vivo [PDF]
Translation of fluorescence imaging using molecularly targeted imaging agents for real-time assessment of surgical margins in the operating room requires a fast and reliable method to predict tumor depth from planar optical imaging.
Achilefu, Samuel +4 more
core +2 more sources
Plasticity of differentiated cells in wound repair and tumorigenesis, Part II: Skin and intestine [PDF]
Recent studies have identified and begun to characterize the roles of regenerative cellular plasticity in many organs. In Part I of our two-part Review, we discussed how cells reprogram following injury to the stomach and pancreas.
Burclaff, Joseph, Mills, Jason C
core +2 more sources
Identification of different types of tumors based on photoacoustic spectral analysis: preclinical feasibility studies on skin tumors. [PDF]
Zhang M +10 more
europepmc +1 more source
Ovarian teratoma in the mare: a review and two cases [PDF]
A 4-year-old Belgian Warmblood mare suffering from pelvic flexure impaction was diagnosed with a teratoma of the left ovary. The enlarged ovary was identified several days after treatment of the impaction.
de Kruif, Aart +10 more
core

