Results 51 to 60 of about 179,563 (276)

Immunogenicity and protective efficacy of nanoparticle formulations of L-SseB against Salmonella infection

Frontiers in Immunology, 2023
Salmonella enterica, a Gram-negative pathogen, has over 2500 serovars that infect a wide range of hosts. In humans, S. enterica causes typhoid or gastroenteritis and is a major public health concern. In this study, SseB (the tip protein of the Salmonella
Sayan Das, Debaki R. Howlader, Ti Lu, Sean K. Whittier, Gang Hu, Simran Sharma, Zackary K. Dietz, Siva S. K. Ratnakaram, David J. Varisco, Robert K. Ernst, William D. Picking, Wendy L. Picking   +11 more
doaj   +1 more source

Public health reforms and the mortality decline in nineteenth‐century Italy

The Economic History Review, EarlyView.
Abstract This study examines the impact of Italy's 1887–8 health reforms on mortality, contributing to the historical debate on the state's role in Europe's health transition. Leveraging event‐study‐style difference‐in‐differences approach, we assess the effectiveness of the Crispi–Pagliani reforms, which strengthened public health governance and ...
Francesco Maria Salvatore Fiore Melacrinis, Mauro Rota   +1 more
wiley   +1 more source

A TLR4 ligand-based adjuvant for promoting the immunogenicity of typhoid subunit vaccines

Frontiers in Immunology
None of the typhoid Vi Polysaccharide (ViPS) subunit vaccines incorporate adjuvants, and the immunogenicity of ViPS vaccines (e.g. Typbar TCV® and Typhim Vi®) is in part due to associated TLR4 ligands such as endotoxin present in these vaccines.
Kishore R. Alugupalli, Kishore R. Alugupalli   +1 more
doaj   +1 more source

Implementation of XpertMalTyph: An Expert System for Medical Diagnosis of the Complications of Malaria and Typhoid [PDF]

, 2013
The dearth of medical experts in the developing world has subjected a large percentage of its populace to preventable ailments and deaths. Also, because of the predominant rural communities, the few medical experts that are available always opt for ...
Adetiba, E., Fatumo, S. A, Onaolapo, J. O.   +2 more
core  

Plant‐produced encapsulin displays non‐typhoidal Salmonella enterica antigens and assembles into mosaic nanoparticles

The FEBS Journal, EarlyView.
This study investigates the potential of encapsulin as an antigen display platform for the development of a candidate Salmonella vaccine for poultry. Encapsulin constructs were transiently expressed in Nicotiana benthamiana where they accumulated to high levels.
Carly A. Charron, Angelo Kaldis, Shabnam Shamriz, Justin B. Renaud, Moussa S. Diarra, Christopher P. Garnham, Rima Menassa   +6 more
wiley   +1 more source

Perceptions of Febrile Illness among Local People Living in Malaria Endemic villages in Central Hill Region of Nepal

Dhaulagiri Journal of Sociology and Anthropology, 2012
Objective of this paper is to explore the perceptions of febrile illness among people living in malaria endemic areas of hill region. Qualitative data were collected from malaria endemic villages in Mahadevesthan VDC of Kavrepalanchok district through in-
C B Budhathoki
doaj   +1 more source

Travelers’ diarrhea and other gastrointestinal symptoms among Boston-area international travelers [PDF]

, 2017
INTRODUCTION: Travelers' diarrhea (TD) and non-TD gastrointestinal (GI) symptoms are common among international travelers. In a study of short-term travelers from Switzerland to developing countries, the most common symptom experienced was severe ...
Barnett, Elizabeth D., Benoit, Christine M., Chen, Lin H., Hamer, Davidson H., Han, Pauline V., Jentes, Emily S., NacLeod, William B., Stoney, Rhett J., Wilson, Mary E.   +8 more
core   +1 more source

Evaluation of the Diagnostic Accuracy of the Quantitative Point‐of‐Care SD Biosensor Standard G6PD Test for Assessment of G6PD Deficiency in Infectious Diseases

International Journal of Laboratory Hematology, EarlyView.
ABSTRACT Background G6PD deficiency affects about 500 million people worldwide and is prevalent in many malaria‐endemic settings. People with G6PD deficiency are at risk of hemolysis when exposed to certain medications, including 8‐aminoquinoline drugs used to treat Plasmodium vivax malaria.
Flavia Regina Medeiros da Silva, Alexandre Gomes Vizzoni, Daniela Mendes‐de‐Almeida, Joanna Bokel, Raquel de Vasconcellos Carvalhaes de Oliveira, André Machado Siqueira, Yasmine Rangel Vieira, Simone da Costa Cruz Silva   +7 more
wiley   +1 more source

Antimicrobial Susceptibility of Salmonella typhi and paratyphi among Pediatric Population at Tertiary Care Center of North Delhi: A Retrospective Study [PDF]

Pediatric Infectious Disease
Background: Enteric fever continues to impact millions of children who lack adequate access to clean water and sanitation. Enteric fever remains a major concern in India with an estimated incidence from hospital surveillance ranging from 12 to 1,622 ...
Shekhar Biswas, Sulagna Tripathy, Arvind Kumar, Sanjay Chattree   +3 more
doaj   +1 more source

The “Reducing Inflammation for Greater Health Trial (RIGHT)” Study—Concept, Rationale, and Design

Journal of the American Geriatrics Society, EarlyView.
ABSTRACT The Reducing Inflammation for Greater Health Trial's (RIGHT) study is a single‐center, randomized, double‐blind, placebo‐controlled trial designed to test whether clazkizumab, an interleukin‐6 (IL‐6) inhibitor, can improve or slow decline in physical, cognitive, and vascular function in older adults, when compared to a placebo.
Sebastian E. Sattui, Marnie Bertolet, Daniel E. Forman, Michelle E. Danielson, Shanshan Yao, Oscar L. Lopez, Nancy W. Glynn, Neelesh K. Nadkarni, Akira Sekikawa, Tullia C. Bruno, Toren Finkel, Anne B. Newman   +11 more
wiley   +1 more source