Results 81 to 90 of about 2,705 (182)

Immunogenicity and Safety Profile of Typhoid Conjugate Vaccine (Vi-DT) Among Nepali Children

Journal of Nepal Health Research Council
Background: Typhoid fever remains a major concern in tropical countries. The availability of an effective vaccine could be an important inclusion to currently available interventions. We reported on our evaluation of the immunogenicity and safety of the
Santosh Adhikari, Ganesh Kumar Rai, Ram Hari Chapagain, Bishnu Rath Giri, Prakash Joshi, Nisha Jyoti Shrestha, Bina Prajapati Manandhar, Suresh Man Tamang, Jessica Maharjan, Bibesh Thapaliya, Birendra Prasad Gupta, Deok Ryun Kim, Sridhar Vemula, Sushant Sahastrabuddhe, Tarun Saluja   +14 more
doaj   +1 more source

Bacterial Extracellular Vesicles in Biomedical Research and Clinical Translation

Microbial Biotechnology, Volume 19, Issue 4, April 2026.
Bacterial membrane vesicle biomedical applications. ABSTRACT Bacterial Extracellular Vesicles (bEVs) are lipid (single‐ or double‐bilayer) nanostructures secreted by virtually all bacteria that play fundamental roles in intercellular communication and have emerged as powerful, multifunctional tools in biomedicine. Their intrinsic ability to encapsulate
Alejandro Arce‐Rodríguez, Javier De la Peña Noya, José Manuel Borrero‐de Acuña   +2 more
wiley   +1 more source

Plant‐produced encapsulin displays non‐typhoidal Salmonella enterica antigens and assembles into mosaic nanoparticles

The FEBS Journal, Volume 293, Issue 7, Page 1908-1929, April 2026.
This study investigates the potential of encapsulin as an antigen display platform for the development of a candidate Salmonella vaccine for poultry. Encapsulin constructs were transiently expressed in Nicotiana benthamiana where they accumulated to high levels.
Carly A. Charron, Angelo Kaldis, Shabnam Shamriz, Justin B. Renaud, Moussa S. Diarra, Christopher P. Garnham, Rima Menassa   +6 more
wiley   +1 more source

Systematic review of studies evaluating the broader economic impact of vaccination in low and middle income countries. [PDF]

, 2012
BACKGROUND: Most health economic evaluations of childhood vaccination only capture the health and short-term economic benefits. Measuring broader, long-term effects of vaccination on productivity and externalities could provide a more complete picture of
Evers, Silvia; id_orcid, van der Putten, Inge, Jit, Mark, van der Putten Inge, Jit Mark, Deogaonkar, Rohan, Evers Silvia, Hutubessy, Raymond, van der Putten, Inge; id_orcid, Silvia Evers, Mark Jit, Hutubessy, Raymond C. W., Deogaonkar Rohan, Evers, Silvia, Hutubessy Raymond, Raymond Hutubessy, Inge van der Putten, Rohan Deogaonkar   +17 more
core   +1 more source

Six-month follow up of a randomized clinical trial-phase I study in Indonesian adults and children: Safety and immunogenicity of Salmonella typhi polysaccharide-diphtheria toxoid (Vi-DT) conjugate vaccine.

PLoS ONE, 2019
IntroductionThere is a high global incidence of typhoid fever, with an annual mortality rate of 200,000 deaths. Typhoid fever also affects younger children, particularly in resource-limited settings in endemic countries.
Bernie Endyarni Medise, Soedjatmiko Soedjatmiko, Iris Rengganis, Hartono Gunardi, Rini Sekartini, Sukamto Koesno, Hindra Irawan Satari, Sri Rezeki Hadinegoro, Jae Seung Yang, Jean-Louis Excler, Sushant Sahastrabuddhe, Mita Puspita, Rini Mulia Sari, Novilia Sjafri Bachtiar   +13 more
doaj   +1 more source

Use of the typhoid conjugate vaccine in endemic settings [PDF]

The Lancet Global Health, 2021
Farhana, Khanam, Firdausi, Qadri
openaire   +2 more sources

Bacteriophage Therapy: Current Strategies and Future Perspectives

MedComm, Volume 7, Issue 3, March 2026.
This manuscript systematically reviews the expanding scope of phage applications. It moves beyond traditional antibacterial use to explore their role in precision therapies against drug‐resistant infections, their synergy with antibiotics, and advanced biomaterial‐assisted delivery systems.
Zihe Zhou, Hanyu Fu, Mengzhe Li, Zhongyu Han, Zhenchao Wu, Huahao Fan, Ning Shen, Jiajia Zheng   +7 more
wiley   +1 more source

Trends and Patterns of Adverse Drug Reaction Reporting in Sierra Leone: A Retrospective Analysis of VigiFlow Data (2008–2022)

Pharmacoepidemiology and Drug Safety, Volume 35, Issue 3, March 2026.
ABSTRACT Purpose Adverse drug reactions (ADRs) present significant obstacles for healthcare systems, impacting both patient safety and the effectiveness of treatments. Despite this, there is a scarcity of research on ADR reports in Sierra Leone, especially over long periods.
Isatu Jalloh, Onome Thomas Abiri, Peter Bai James, Rajesh Vagiri, Neelaveni Padayachee   +4 more
wiley   +1 more source

Drinking Water Quality Regulations: A Contrast Between Germany and Latin America

Environmental Quality Management, Volume 35, Issue 3, Spring 2026.
ABSTRACT This article investigates the differences among drinking water quality standards adopted in Latin American countries, Mexico, Cuba, and the European Union, considering the growing challenge of ensuring safe drinking water in a context marked by environmental pressures, climate change, and the occurrence of emerging contaminants. The study aims
Eduardo Saldanha Vogelmann, Juliana Prevedello, Gizachew Ayalew Tiruneh   +2 more
wiley   +1 more source

Harnessing controlled human infection models to accelerate vaccine development for neglected tropical diseases: Lessons from leishmaniasis

European Journal of Clinical Investigation, Volume 56, Issue 1, January 2026.
Controlled Human Infection Models (CHIMs) offer a powerful approach to accelerate vaccine development for neglected tropical diseases (NTDs). This review highlights scientific and translational advances enabled by CHIMs, with a focus on a novel Leishmania major model.
Vivak Parkash
wiley   +1 more source