Results 61 to 70 of about 2,440 (155)

Global diversity and antimicrobial resistance of typhoid fever pathogens: Insights from a meta-analysis of 13,000 Salmonella Typhi genomes

eLife, 2023
Background: The Global Typhoid Genomics Consortium was established to bring together the typhoid research community to aggregate and analyse Salmonella enterica serovar Typhi (Typhi) genomic data to inform public health action. This analysis, which marks
Megan E Carey, Zoe A Dyson, Danielle J Ingle, Afreenish Amir, Mabel K Aworh, Marie Anne Chattaway, Ka Lip Chew, John A Crump, Nicholas A Feasey, Benjamin P Howden, Karen H Keddy, Mailis Maes, Christopher M Parry, Sandra Van Puyvelde, Hattie E Webb, Ayorinde Oluwatobiloba Afolayan, Anna P Alexander, Shalini Anandan, Jason R Andrews, Philip M Ashton, Buddha Basnyat, Ashish Bavdekar, Isaac I Bogoch, John D Clemens, Kesia Esther da Silva, Anuradha De, Joep de Ligt, Paula Lucia Diaz Guevara, Christiane Dolecek, Shanta Dutta, Marthie M Ehlers, Louise Francois Watkins, Denise O Garrett, Gauri Godbole, Melita A Gordon, Andrew R Greenhill, Chelsey Griffin, Madhu Gupta, Rene S Hendriksen, Robert S Heyderman, Yogesh Hooda, Juan Carlos Hormazabal, Odion O Ikhimiukor, Junaid Iqbal, Jobin John Jacob, Claire Jenkins, Dasaratha Ramaiah Jinka, Jacob John, Gagandeep Kang, Abdoulie Kanteh, Arti Kapil, Abhilasha Karkey, Samuel Kariuki, Robert A Kingsley, Roshine Mary Koshy, AC Lauer, Myron M Levine, Ravikumar Kadahalli Lingegowda, Stephen P Luby, Grant Austin Mackenzie, Tapfumanei Mashe, Chisomo Msefula, Ankur Mutreja, Geetha Nagaraj, Savitha Nagaraj, Satheesh Nair, Take K Naseri, Susana Nimarota-Brown, Elisabeth Njamkepo, Iruka N Okeke, Sulochana Putli Bai Perumal, Andrew J Pollard, Agila Kumari Pragasam, Firdausi Qadri, Farah N Qamar, Sadia Isfat Ara Rahman, Savitra Devi Rambocus, David A Rasko, Pallab Ray, Roy Robins-Browne, Temsunaro Rongsen-Chandola, Jean Pierre Rutanga, Samir K Saha, Senjuti Saha, Karnika Saigal, Mohammad Saiful Islam Sajib, Jessica C Seidman, Jivan Shakya, Varun Shamanna, Jayanthi Shastri, Rajeev Shrestha, Sonia Sia, Michael J Sikorski, Ashita Singh, Anthony M Smith, Kaitlin A Tagg, Dipesh Tamrakar, Arif Mohammed Tanmoy, Maria Thomas, Mathew S Thomas, Robert Thomsen, Nicholas R Thomson, Siaosi Tupua, Krista Vaidya, Mary Valcanis, Balaji Veeraraghavan, François-Xavier Weill, Jackie Wright, Gordon Dougan, Silvia Argimón, Jacqueline A Keane, David M Aanensen, Stephen Baker, Kathryn E Holt, Global Typhoid Genomics Consortium Group Authorship   +114 more
doaj   +1 more source

Modeling the potential impact of typhoid conjugate vaccines [PDF]

International Journal of Infectious Diseases, 2014
Sub-Saharan Africa is urbanizing at a rate of 3-5% with>70% of new urban residents settling in informal settlements, which are urban slums with high population density and limited sanitation, hygiene and water quality. Likewise, municipalities in south and southeast Asia are dominated by similar informal settlements.
V.E. Pitzer, C.C. Bowles, S. Baker, B.T. Grenfell   +3 more
openaire   +2 more sources

Vi-Vaccinations Induce Heterogeneous Plasma Cell Responses That Associate With Protection From Typhoid Fever

Frontiers in Immunology, 2020
Vi-polysaccharide conjugate vaccines are efficacious against cases of typhoid fever; however, an absolute correlate of protection is not established. In this study, we investigated the leukocyte response to a Vi-tetanus toxoid conjugate vaccine (Vi-TT ...
Deborah L. Cross, Marije K. Verheul, Michael D. Leipold, Gerlinde Obermoser, Celina Jin, Elizabeth Jones, Joshua S. Starr, Irina Mohorianu, Christoph J. Blohmke, Holden T. Maecker, Giorgio Napolitani, Jennifer Hill, Andrew J. Pollard   +12 more
doaj   +1 more source

Immunogenicity and Safety Profile of Typhoid Conjugate Vaccine (Vi-DT) Among Nepali Children

Journal of Nepal Health Research Council
Background: Typhoid fever remains a major concern in tropical countries. The availability of an effective vaccine could be an important inclusion to currently available interventions. We reported on our evaluation of the immunogenicity and safety of the
Santosh Adhikari, Ganesh Kumar Rai, Ram Hari Chapagain, Bishnu Rath Giri, Prakash Joshi, Nisha Jyoti Shrestha, Bina Prajapati Manandhar, Suresh Man Tamang, Jessica Maharjan, Bibesh Thapaliya, Birendra Prasad Gupta, Deok Ryun Kim, Sridhar Vemula, Sushant Sahastrabuddhe, Tarun Saluja   +14 more
doaj   +1 more source

Characterization of Citrobacter sp. line 328 as a source of Vi for a Vi-CRM197 glycoconjugate vaccine against Salmonella Typhi

Journal of Infection in Developing Countries, 2012
Introduction: Salmonella enterica serovar Typhi is the causative agent of typhoid fever with over 22 million cases and over 200,000 deaths reported annually.
Simona Rondini, Francesca Micoli, Luisa Lanzilao, Ivan Pisoni, Vito Di Cioccio, Allan J Saul, Laura B Martin   +6 more
doaj   +1 more source

Infectious Diseases and Antimicrobial Resistance in the Gaza Strip: Epidemiological Drivers, Health System Disruptions, and Global Implications: A Narrative Review

Health Science Reports, Volume 9, Issue 5, May 2026.
ABSTRACT Background and Aims The Gaza Strip has faced prolonged blockade, recurrent military conflicts, and systemic infrastructure collapse since October 2023, resulting in an unprecedented public health crisis characterized by surging infectious diseases and antimicrobial resistance (AMR).
Nima Farhadi, Aref Yarahmadi, Hamed Afkhami   +2 more
wiley   +1 more source

Use of the typhoid conjugate vaccine in endemic settings [PDF]

The Lancet Global Health, 2021
Farhana, Khanam, Firdausi, Qadri
openaire   +2 more sources

“Reactions in Leprosy: Updated Insights Into Pathophysiology, Clinical Spectrum, and Therapeutic Approaches—A Narrative Review”

Health Science Reports, Volume 9, Issue 5, May 2026.
ABSTRACT Background and Aims Reaction in leprosy is an immune‐mediated acute inflammatory episodes that occur in the natural course of Hansen's disease. Reaction can occur before, during, or after starting multidrug therapy and is a major cause of nerve damage, morbidity, and disability in affected individuals.
Bhaskar Gupta, Manesha Singh, Mohamad Goldust, Kinnor Das, Surajit Gorai, Prajwal Pudasaini, Seema Sitaula, Achyut Pokhrel, Esna Thapa, Sunil Jaiswal   +9 more
wiley   +1 more source

Barriers to typhoid fever vaccine access in endemic countries

Research and Reports in Tropical Medicine, 2017
M Imran Khan,1 Carlos Franco-Paredes,2,3 Sushant Sahastrabuddhe,4 R Leon Ochiai,5 Vittal Mogasale,4 Bradford D Gessner6 1Center of Excellence in Women and Child Health, The Aga Khan University, Karachi, Pakistan; 2Hospital Infantil de México ...
Khan MI, Franco-Paredes C, Sahastrabuddhe S, Ochiai RL, Mogasale V, BD Gessner   +5 more
doaj  

Six-month follow up of a randomized clinical trial-phase I study in Indonesian adults and children: Safety and immunogenicity of Salmonella typhi polysaccharide-diphtheria toxoid (Vi-DT) conjugate vaccine.

PLoS ONE, 2019
IntroductionThere is a high global incidence of typhoid fever, with an annual mortality rate of 200,000 deaths. Typhoid fever also affects younger children, particularly in resource-limited settings in endemic countries.
Bernie Endyarni Medise, Soedjatmiko Soedjatmiko, Iris Rengganis, Hartono Gunardi, Rini Sekartini, Sukamto Koesno, Hindra Irawan Satari, Sri Rezeki Hadinegoro, Jae Seung Yang, Jean-Louis Excler, Sushant Sahastrabuddhe, Mita Puspita, Rini Mulia Sari, Novilia Sjafri Bachtiar   +13 more
doaj   +1 more source