Results 41 to 50 of about 2,705 (182)

A randomised trial evaluating the safety and immunogenicity of the novel single oral dose typhoid vaccine M01ZH09 in healthy Vietnamese children. [PDF]

, 2010
BACKGROUND: The emergence of drug resistant typhoid fever is a major public health problem, especially in Asia. An oral single dose typhoid vaccine would have major advantages.
Schultsz, C, To, S.D., Vinh Chau Nguyen Van, Dolecek, C., Thi Diem Ha Tran, Dolecek, Christiane, Nguyen, V.M.H., Van Vinh Chau Nguyen, Upton Anthony, Nguyen, T.D., Thi Dung Nguyen, James P May, Marques, F, Nguyen, T.T., Schultsz, Constance, Glover, Clare, Upton, A., Nguyen, Thi Cam Binh, Stockwell, E, Hoang Nguyen Van Minh, Schultsz, C., Farrar, Jeremy, Upton, A, Glover, C., Van Minh Hoang Nguyen, Nguyen, Thanh Truong, Filipe Marques, Nguyen, TCB, James P. May, Pham Van Toi, James I. Campbell, Stockwell, E., Pham, Van Toi, Elaine Stockwell, Nga Tran Thi Thu, Ninh, TTV, Tran, T.D.H., May, James P, James I Campbell, To, Song Diep, Nguyen, T.C.B., Toi Pham Van, Tran, Thi Thu Nga, May, J.P., Tran, TTN, Budhram, R., Tran, T.T.N., Simmons, Cameron P, Van Toi Pham, Tran, N.B.C., Lam, W., Glover Clare, Campbell, J.I., Marques, F., Ha Tran Thi Diem, Bich Chau Tran Nguyen, Tran, TDH, Nguyen, VVC, Campbell, JI, Ninh Thi Thanh Van, To, SD, Schultsz Constance, Dougan, Gordon, Ninh, Tran, Lam, Winnie, Nguyen, V.V.C., Campbell James I., Farrar Jeremy, Dolecek, C, Upton, Anthony, Christiane Dolecek, Cameron P. Simmons, Simmons, Cameron, Stockwell, Elaine, Tran, Tinh Hien, Ninh, Thi Thanh Van, Nguyen Thi Cam Binh, Budhram, Ronald, Nguyen Thi Dung, Dung Nguyen Thi, Hien Tran Tinh, Cao, Thu Thuy, Van Ninh Thi Thanh, Cao, T.T., Simmons, Cameron P., Constance Schultsz, Tran, NBC, Tran Tinh Hien, Stockwell Elaine, Nguyen, Van Minh Hoang, Dolecek Christiane, Tran, TH, Lam Winnie, Campbell, James I, Nguyen, Van Vinh Chau, Tran Thi Diem Ha, Nguyen, Thi Dung, Winnie Lam, Gordon Dougan, May James P., Farrar, J, Nguyen Bich Chau Tran, Nguyen, TC, Nguyen, TD, Jeremy Farrar, Tran, TT, Cao Thu Thuy, Tinh Hien Tran, Thi Thanh Van Ninh, Budhram, R, Pham, V.T., Thu Thuy Cao, Simmons, C.P., Nguyen, TT, Glover, C, Tran, TD, Thuy Cao Thu, Ninh, TT, Simmons, CP, May, James P., Dougan, G., Ronald Budhram, Pham, V.M., Thi Cam Binh Nguyen, Pham, Van Minh, Lam, W, Thanh Truong Nguyen, Nguyen Van Minh Hoang, Farrar, J., Van Minh Pham, Tran, Nguyen Bich Chau, Thi Thu Nga Tran, Song Diep To, Nguyen Thanh Truong, Dougan Gordon, Pham Van Minh, Cao, TT, Clare Glover, Nguyen Van Vinh Chau, To Song Diep, Ninh, T.T.V., Tran, NB, Nguyen, MV, Budhram Ronald, Tran Nguyen Bich Chau, Marques, Filipe, Campbell, James I., Tran, Thi Diem Ha, Simmons Cameron P., Binh Nguyen Thi Cam, Tran, T.H., Cameron P Simmons, Pham, VM, Nguyen, VM, Tran Thi Thu Nga, Marques Filipe, Pham, VT, Nguyen, VV, Minh Pham Van, May, JP, Dougan, G, Anthony Upton, Truong Nguyen Thanh   +162 more
core   +1 more source

The Design and Analysis of Seroefficacy Studies for Typhoid Conjugate Vaccines [PDF]

Clinical Infectious Diseases, 2019
AbstractBackgroundDemonstrating the efficacy of new Vi-conjugate typhoid vaccines is challenging, due to the cost of field trials requiring tens of thousands of participants. New trial designs that use serologically defined typhoid infections (seroefficacy trials) rather than blood culture positivity as a study endpoint may be useful to assess efficacy
Liu, X, Pitzer, V, Pollard, A, Voysey, M
openaire   +3 more sources

A novel Vi-diphtheria toxoid typhoid conjugate vaccine is safe and can induce immunogenicity in healthy Indonesian children 2–11 years: a phase II preliminary report

BMC Pediatrics, 2020
Background Typhoid fever caused by Salmonella enteric serovar Typhi (S. Typhi) is a common cause of morbidity in the world. In 2017, 14.3 million cases of Typhoid and paratyphoid fever occurred globally.
Bernie Endyarni Medise, Soedjatmiko Soedjatmiko, Hartono Gunardi, Rini Sekartini, Hindra Irawan Satari, Sri Rezeki Hadinegoro, Angga Wirahmadi, Mita Puspita, Rini Mulia Sari, Jae Seung Yang, Arijit Sil, Sushant Sahastrabuddhe, Novilia Sjafri Bachtiar   +12 more
doaj   +1 more source

Target identification for prevention and therapy of "Salmonella" infections [PDF]

, 2014
In this thesis we investigated maintenance requirements of Salmonella during chronic infections, and determined the relevant antigen properties that might facilitate the development of Salmonella vaccines. Overall, we wanted to achieve two goals: a)To
Barat, Somedutta
core   +1 more source

Efficacy of typhoid conjugate vaccine: final analysis of a 4-year, phase 3, randomised controlled trial in Malawian children [PDF]

Lancet, The
Pratiksha Patel, Richard Wachepa, Shrimati Datta   +2 more
exaly   +2 more sources

Longevity of immune response after a single dose of typhoid conjugate vaccine against Salmonella Typhi among children in Hyderabad, Pakistan [PDF]

International Journal of Infectious Diseases
Aneeta Hotwani, Najeeb Rahman
exaly   +2 more sources

Safety and immunogenicity of Vi-DT conjugate vaccine among 6-23-month-old children: Phase II, randomized, dose-scheduling, observer-blind Study

EClinicalMedicine, 2020
Background: Typhoid causes significant mortality among young children in resource-limited settings. Conjugate typhoid vaccines could significantly reduce typhoid-related child deaths, but only one WHO-prequalified typhoid conjugate vaccine exists for ...
Maria Rosario Capeding, Arijit Sil, Birkneh Tilahun Tadesse, Tarun Saluja, Samuel Teshome, Edison Alberto, Deok Ryun Kim, Eun Lyeong Park, Ju Yeon Park, Jae Seung Yang, Suchada Chinaworapong, Jiwook Park, Sue-Kyoung Jo, Yun Chon, Seon-Young Yang, Ji Hwa Ryu, Inho Cheong, Kyu-Young Shim, Yoonyeong Lee, Hun Kim, Julia A. Lynch, Jerome H. Kim, Jean-Louis Excler, T. Anh Wartel, Sushant Sahastrabuddhe   +24 more
doaj   +1 more source

A Salmonella Typhi Controlled Human Infection Study for Assessing Correlation between Bactericidal Antibodies and Protection against Infection Induced by Typhoid Vaccination

Microorganisms, 2021
Vi-polysaccharide conjugate vaccines are efficacious against typhoid fever in children living in endemic settings, their recent deployment is a promising step in the control of typhoid fever.
Elizabeth Jones, Celina Jin, Lisa Stockdale, Christina Dold, Andrew J. Pollard, Jennifer Hill   +5 more
doaj   +1 more source

Characteristics of the children approached for participation in typhoid conjugate vaccine (TCV) coverage survey.

, 2023
Characteristics of the children approached for participation in typhoid conjugate vaccine (TCV) coverage survey.
Sonia Qureshi (6940871), Rehana A. Salam (8098277), Tahira Sadaf (16792862), Zoya Haq (11140940), Mohammad Tahir Yousafzai (8982443), Farah Naz Qamar (6940889), Rabab Batool (16792856), Rafey Ali (16792859), Miqdad Ali (16792865)   +8 more
core   +1 more source

A Study on Longevity of Immune Response after Vaccination with Salmonella Typhi Vi Conjugate Vaccine (Pedatyph™) in Children [PDF]

Journal of Clinical and Diagnostic Research, 2015
Background and Objectives: Owing to the limitations of the conventional polysaccharide vaccines, global efforts have been made to develop conjugated polysaccharide vaccines for typhoid. Duration of immune response induced by these vaccines is critical
Balaji Chinnasami, Kanimozhi Sadasivam, Aravindhan Vivekanandhan, Prema Arunachalam, Sekar Pasupathy   +4 more
doaj   +1 more source