Results 21 to 30 of about 2,705 (182)

An observer-blinded, cluster randomised trial of a typhoid conjugate vaccine in an urban South Indian cohort [PDF]

Trials, 2023
Background Typhoid fever causes nearly 110,000 deaths among 9.24 million cases globally and disproportionately affects developing countries. As a control measure in such regions, typhoid conjugate vaccines (TCVs) are recommended by the World Health ...
Nikhil Sahai, Dilesh Kumar Arunachalam, Tim Morris, Andrew Copas, Prasanna Samuel, Venkata Raghava Mohan, Vinod Abraham, Joshua Anish Selwyn, Praveen Kumar, Winsley Rose, Veeraraghavan Balaji, Gagandeep Kang, Jacob John   +12 more
doaj   +2 more sources

Typhoid Conjugate Vaccine: An Urgent Tool to Combat Typhoid and Tackle Antimicrobial Resistance. [PDF]

J Infect Dis, 2021
Abstract Typhoid is endemic in many countries in South Asia and sub-Saharan Africa. The high burden of this age-old, preventable disease exacerbates constraints on the health systems of these countries. Currently, most patients are treated effectively in the community or outpatient departments, but with rising antimicrobial resistance ...
Saha SK, Tabassum N, Saha S.
europepmc   +4 more sources

Strategies to Improve Coverage of Typhoid Conjugate Vaccine (TCV) Immunization Campaign in Karachi, Pakistan

Vaccines, 2020
The emergence and spread of extensively drug-resistant (XDR) typhoid in Karachi, Pakistan led to an outbreak response in Lyari Town, Karachi utilizing a mass immunization campaign with typhoid conjugate vaccine (TCV), Typbar TCV®.
Farah Naz Qamar, Rabab Batool, Sonia Qureshi, Miqdad Ali, Tahira Sadaf, Junaid Mehmood, Khalid Iqbal, Akram Sultan, Noah Duff, Mohammad Tahir Yousafzai   +9 more
doaj   +3 more sources

Barriers to typhoid fever vaccine access in endemic countries

Research and Reports in Tropical Medicine, 2017
M Imran Khan,1 Carlos Franco-Paredes,2,3 Sushant Sahastrabuddhe,4 R Leon Ochiai,5 Vittal Mogasale,4 Bradford D Gessner6 1Center of Excellence in Women and Child Health, The Aga Khan University, Karachi, Pakistan; 2Hospital Infantil de México ...
Khan MI, Franco-Paredes C, Sahastrabuddhe S, Ochiai RL, Mogasale V, BD Gessner   +5 more
doaj   +1 more source

A phase II clinical trial of a Vi-DT typhoid conjugate vaccine in healthy Indonesian adolescents and adults: one-month evaluation of safety and immunogenicity [PDF]

Tropical Diseases, Travel Medicine and Vaccines
Background Typhoid fever is commonly found until today, especially in developing countries. It has fatal complications and measures must be taken to reduce the incidence of typhoid. Vaccinations are a key factor in prevention.
Sukamto Koesnoe, Bernie Endyarni Medise, Iris Rengganis, Sri Rezeki Hadinegoro, Mita Puspita, Rini Mulia Sari, Jae Seung Yang, Sushant Sahastrabuddhe, Soedjatmiko, Hartono Gunardi, Rini Sekartini, Angga Wirahmadi, Aria Kekalih, Sreshta Mukhi, Hindra Irawan Satari, Novilia Sjafri Bachtiar   +15 more
doaj   +2 more sources

Effective strategies for typhoid conjugate vaccine delivery: Health and economic insights from the 2015 Kampala outbreak. [PDF]

PLoS Neglected Tropical Diseases
Typhoid fever remains a major public health threat in low- and middle-income countries (LMICs), where inadequate access to clean water and sanitation drives recurrent outbreaks.
Yeonsu Lee, Pamela Kim N Salonga, Changdae Son, Geunsoo Jang, Dae-Hyup Koh, Jong-Hoon Kim, Hyojung Lee   +6 more
doaj   +2 more sources

Typhoid conjugate vaccines: is a single dose enough for durable protection?

Expert Review of Vaccines
Introduction Typhoid fever is widespread in developing countries. Most typhoid vaccines have gone into some disrepute for their substantial side effects and low efficacy.
Vipin M. Vashishtha, Puneet Kumar
doaj   +2 more sources

Typhoid Conjugate Vaccines and Enteric Fever Control: Where to Next? [PDF]

Clinical Infectious Diseases, 2020
Abstract After the unprecedented success and acceleration of the global agenda towards typhoid fever control with a strong World Health Organization recommendation and the approval of funding from Gavi, the Vaccine Alliance (Gavi), for the use of a new typhoid conjugate vaccine (TCV), we should turn our minds to the challenges that ...
Steele, AD, Carey, ME, Kumar, S, MacLennan, CA, Ma, L-F, Diaz, Z, Zaidi, AKM   +6 more
openaire   +4 more sources

Safety and immunogenicity of Vi-diphtheria toxoid typhoid conjugate vaccine among children below 2 years: a systematic review and meta-analysis [PDF]

Frontiers in Microbiology
BackgroundThe Vi-diphtheria toxoid typhoid conjugate vaccine (Vi-DT) has shown promising results in preventing typhoid fever in children under 2 years of age.
Amira Mohamed Taha, Khaled Abouelmagd, Abdelrahman Mohamed Mahmoud, Mohamed Hamouda Elkasaby, Dang Nguyen, Ryan Ahmed, Pari Patel, D. Katterine Bonilla-Aldana, Camila Luna, Alfonso J. Rodriguez-Morales, Alfonso J. Rodriguez-Morales, Alfonso J. Rodriguez-Morales   +11 more
doaj   +2 more sources

Modeling the potential impact of typhoid conjugate vaccines [PDF]

International Journal of Infectious Diseases, 2014
Sub-Saharan Africa is urbanizing at a rate of 3-5% with>70% of new urban residents settling in informal settlements, which are urban slums with high population density and limited sanitation, hygiene and water quality. Likewise, municipalities in south and southeast Asia are dominated by similar informal settlements.
V.E. Pitzer, C.C. Bowles, S. Baker, B.T. Grenfell   +3 more
openaire   +3 more sources