Results 21 to 30 of about 2,440 (155)

Evidence of Extended Thermo-Stability of Typhoid Polysaccharide Conjugate Vaccines [PDF]

Microorganisms, 2021
Typhoid conjugate vaccines (TCV) are effective in preventing enteric fever caused by Salmonella enterica serovar Typhi in Southeast Asia and Africa. To facilitate vaccination with the Vi capsular polysaccharide–tetanus toxoid conjugate vaccine, Typbar ...
Fang Gao, Kay Lockyer, Alastair Logan, Sarah Davis, Barbara Bolgiano, Sjoerd Rijpkema, Gopal Singh, Sai D. Prasad, Samuel Pradeep Dondapati, Gurbaksh Singh Sounkhla   +9 more
doaj   +3 more sources

Safety and immunogenicity of Vi-diphtheria toxoid typhoid conjugate vaccine among children below 2 years: a systematic review and meta-analysis [PDF]

Frontiers in Microbiology
BackgroundThe Vi-diphtheria toxoid typhoid conjugate vaccine (Vi-DT) has shown promising results in preventing typhoid fever in children under 2 years of age.
Amira Mohamed Taha, Khaled Abouelmagd, Abdelrahman Mohamed Mahmoud, Mohamed Hamouda Elkasaby, Dang Nguyen, Ryan Ahmed, Pari Patel, D. Katterine Bonilla-Aldana, Camila Luna, Alfonso J. Rodriguez-Morales, Alfonso J. Rodriguez-Morales, Alfonso J. Rodriguez-Morales   +11 more
doaj   +2 more sources

Single and two-dose typhoid conjugate vaccine safety and immunogenicity in HIV-exposed uninfected and HIV-unexposed uninfected Malawian children [PDF]

Human Vaccines & Immunotherapeutics
Vaccine safety and immunogenicity data in human immunodeficiency virus (HIV)-exposed uninfected (HEU) children are important for decision-making in HIV and typhoid co-endemic countries.
Nginache Nampota-Nkomba, Osward M. Nyirenda, Victoria Mapemba, Rhoda Masonga, Priyanka D. Patel, Theresa Misiri, Felistas Mwakiseghile, Richard Wachepa, John M. Ndaferankhande, Bright Lipenga, Pratiksha Patel, Happy Banda, Jennifer Oshinsky, Marcela F. Pasetti, Robert S. Heyderman, Leslie P. Jamka, Divya Hosangadi, Shrimati Datta, Melita A. Gordon, Kathleen M. Neuzil, Matthew B. Laurens   +20 more
doaj   +2 more sources

Safety and immunogenicity of conjugate vaccine for typhoid (Vi-DT): Finding from an observer-blind, active-controlled, randomized, non-inferiority, phase III clinical trial among healthy volunteers

Human Vaccines & Immunotherapeutics
Typhoid fever is a significant public health concern with most of the sufferers between 15 and 25 y of age in Nepal. We undertook this study to demonstrate Vi polysaccharide conjugated with diphtheria toxoid (Vi-DT) conjugate vaccine which is non ...
Dipesh Tamrakar, Pranodan Poudel, Pragya Thapa, Srijana Singh, Amit Khadgi, Sameera Thapa, Rajendra Tamrakar, Anmol Shrestha, Surendra Madhup, Ganesh Kumar Rai, Birendra Prasad Gupta, Tarun Saluja, Sushant Sahastrabuddhe, Rajeev Shrestha   +13 more
doaj   +3 more sources

Immunogenicity and reactogenicity of a booster dose of a typhoid conjugate vaccine (TCV) in Malawian pre-school children [PDF]

EClinicalMedicine
Kathleen Neuzil, Matthew B Laurens, Leslie P Jamka   +2 more
exaly   +2 more sources

Introduction of Typhoid Conjugate Vaccines in Africa and Asia [PDF]

Clinical Infectious Diseases, 2019
Typhoid fever continues to be a major public health concern, particularly in many low- and middle-income countries. The current threats of increasing antimicrobial resistance, urbanization, and climate change elevate the urgency for better prevention and control efforts for typhoid fever.
Neuzil, K, Pollard, A, Marfin, A
openaire   +2 more sources

Longevity of immune response after a single dose of typhoid conjugate vaccine against Salmonella Typhi among children in Hyderabad, Pakistan [PDF]

International Journal of Infectious Diseases
Seema Irfan, Ibtisam Qazi, Aneeta Hotwani   +2 more
exaly   +2 more sources

Typhoid conjugate vaccines: making vaccine history in Africa [PDF]

Expert Review of Vaccines, 2018
The 21 February 2018 was a day in vaccine history as 4-year old Golden Kondowe became the first child in Africa to be enrolled in an individually randomized vaccine efficacy trial of a newly WHO pr...
James E. Meiring, Pratiksha Patel, Priyanka Patel, Melita A. Gordon   +3 more
openaire   +3 more sources

Typhoid Conjugate Vaccines: Advancing the Research and Public Health Agendas [PDF]

The Journal of Infectious Diseases, 2021
Abstract The disease burden of typhoid fever remains high in endemic areas in Asia and Africa, especially in children. Recent clinical trials conducted by the Typhoid Vaccine Acceleration Consortium show typhoid conjugate vaccine (TCV) to be safe, immunogenic, and efficacious at preventing blood culture-confirmed typhoid fever in African
Birkhold, M, Mwisongo, A, Pollard, AJ, Neuzil, KM   +3 more
openaire   +2 more sources

A Race against Time: Reduced Azithromycin Susceptibility in Salmonella enterica Serovar Typhi in Pakistan

mSphere, 2020
Antimicrobial resistance is an ongoing issue in the treatment of typhoid fever. Resistance to first-line antimicrobials and extensively drug resistant (XDR) Salmonella Typhi isolates in Pakistan have left azithromycin as the only remaining effective oral
Junaid Iqbal, Irum F. Dehraj, Megan E. Carey, Zoe A. Dyson, Denise Garrett, Jessica C. Seidman, Furqan Kabir, Senjuti Saha, Stephen Baker, Farah N. Qamar   +9 more
doaj   +3 more sources